Felipe Prósper

Research interests

Publications

• Lipid nanoparticles for siRNA delivery in cancer treatment

  Journal of Controlled Release · 2023 · 10.1016/j.jconrel.2023.07.054

• Single-Cell RNA Sequencing Analysis Reveals a Crucial Role for CTHRC1 (Collagen Triple Helix Repeat Containing 1) Cardiac Fibroblasts After Myocardial Infarction

  Circulation · 2020 · 10.1161/circulationaha.119.044557

• Adipose-derived mesenchymal stromal cells for the treatment of patients with severe SARS-CoV-2 pneumonia requiring mechanical ventilation. A proof of concept study

  EClinicalMedicine · 2020 · 10.1016/j.eclinm.2020.100454

• Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

  Cell · 2020 · https://doi.org/10.1016/j.cell.2020.04.004

• Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

  Journal for ImmunoTherapy of Cancer · 2020 · https://doi.org/10.1136/jitc-2019-000337

• The Mechanism of Action of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma

  Clinical Cancer Research · 2019 · 10.1158/1078-0432.ccr-18-1597

• HDAC Inhibitors in Acute Myeloid Leukemia

  Cancers · 2019 · 10.3390/cancers11111794

• Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression

  Nature Medicine · 2019 · 10.1038/s41591-019-0499-y

• The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

  Nature Medicine · 2018 · 10.1038/s41591-018-0028-4

• Target Expression, Generation, Preclinical Activity, and Pharmacokinetics of the BCMA-T Cell Bispecific Antibody EM801 for Multiple Myeloma Treatment

  Cancer Cell · 2017 · https://doi.org/10.1016/j.ccell.2017.02.002

• Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II)

  Journal of Translational Medicine · 2016 · 10.1186/s12967-016-0998-2

• Whole-genome fingerprint of the DNA methylome during human B cell differentiation

  Nature Genetics · 2015 · 10.1038/ng.3291

• Lenalidomide plus Dexamethasone for High-Risk Smoldering Multiple Myeloma

  New England Journal of Medicine · 2013 · https://doi.org/10.1056/nejmoa1300439

• A DNA methylation fingerprint of 1628 human samples

  Genome Research · 2011 · https://doi.org/10.1101/gr.119867.110

• Epigenetic Silencing of the Tumor Suppressor MicroRNA Hsa-miR-124a Regulates CDK6 Expression and Confers a Poor Prognosis in Acute Lymphoblastic Leukemia

  Cancer Research · 2009 · 10.1158/0008-5472.can-08-4025

• Epigenetic regulation of microRNA expression in colorectal cancer

  International Journal of Cancer · 2009 · https://doi.org/10.1002/ijc.24638

• Transplantation of Adipose Derived Stromal Cells is Associated with Functional Improvement in a Rat Model of Chronic Myocardial Infarction

  European Journal of Heart Failure · 2008 · 10.1016/j.ejheart.2008.03.017

• Down-Regulation of hsa-miR-10a in Chronic Myeloid Leukemia CD34+ Cells Increases USF2-Mediated Cell Growth

  Molecular Cancer Research · 2008 · 10.1158/1541-7786.mcr-08-0167

• Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: results of a multicenter phase 1/2 study

  Blood · 2006 · https://doi.org/10.1182/blood-2006-04-019778

• Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas

  Blood · 2006 · 10.1182/blood-2006-06-026500

• Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia

  Oncogene · 2005 · 10.1038/sj.onc.1208866

• Promoter hypermethylation of cancer-related genes: a strong independent prognostic factor in acute lymphoblastic leukemia

  Blood · 2004 · 10.1182/blood-2004-03-0954

• Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB Activation

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m206473200

• Blockade of the Bcr-Abl Kinase Activity Induces Apoptosis of Chronic Myelogenous Leukemia Cells by Suppressing Signal Transducer and Activator of Transcription 5–Dependent Expression of Bcl-XL

  The Journal of Experimental Medicine · 2000 · 10.1084/jem.191.6.977

• Erythropoietin Can Induce the Expression of Bcl-xLthrough Stat5 in Erythropoietin-dependent Progenitor Cell Lines

  Journal of Biological Chemistry · 1999 · 10.1074/jbc.274.32.22165

Current projects

No projects listed.