Martin Widschwendter

Research interests

Publications

• Validation of biomarkers of aging

  Nature Medicine · 2024 · https://doi.org/10.1038/s41591-023-02784-9

• Biomarkers of aging for the identification and evaluation of longevity interventions

  Cell · 2023 · 10.1016/j.cell.2023.08.003

• Personalized early detection and prevention of breast cancer: ENVISION consensus statement

  Nature Reviews Clinical Oncology · 2020 · https://doi.org/10.1038/s41571-020-0388-9

• A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases

  Modern Pathology · 2019 · https://doi.org/10.1038/s41379-019-0302-0

• Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study

  The Journal of Pathology Clinical Research · 2018 · https://doi.org/10.1002/cjp2.109

• A Novel Cell-Type Deconvolution Algorithm Reveals Substantial Contamination by Immune Cells in Saliva, Buccal and Cervix

  Epigenomics · 2018 · https://doi.org/10.2217/epi-2018-0037

• Dose-Response Association of CD8 + Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer

  JAMA Oncology · 2017 · https://doi.org/10.1001/jamaoncol.2017.3290

• Menopause accelerates biological aging

  Proceedings of the National Academy of Sciences · 2016 · 10.1073/pnas.1604558113

• Correlation of an epigenetic mitotic clock with cancer risk

  Genome biology · 2016 · 10.1186/s13059-016-1064-3

• DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms10478

• Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial

  The Lancet · 2015 · 10.1016/s0140-6736(15)01224-6

• Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies

  Bioinformatics · 2011 · 10.1093/bioinformatics/btr171

• Tubal ligation and the risk of ovarian cancer: review and meta-analysis

  Human Reproduction Update · 2010 · 10.1093/humupd/dmq030

• Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

  Nature · 2010 · 10.1038/nature09387

• A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.668

• Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

  Genome Research · 2010 · 10.1101/gr.103606.109

• An Epigenetic Signature in Peripheral Blood Predicts Active Ovarian Cancer

  PLoS ONE · 2009 · 10.1371/journal.pone.0008274

• FBXW7/hCDC4 Is a General Tumor Suppressor in Human Cancer

  Cancer Research · 2007 · 10.1158/0008-5472.can-07-1320

• Epigenetic stem cell signature in cancer

  Nature Genetics · 2006 · 10.1038/ng1941

• CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

  Nature Genetics · 2006 · https://doi.org/10.1038/ng1834

• Circulating Tumor-Specific DNA: A Marker for Monitoring Efficacy of Adjuvant Therapy in Cancer Patients

  Cancer Research · 2005 · 10.1158/0008-5472.can-04-2438

• Methylation changes in faecal DNA: a marker for colorectal cancer screening?

  The Lancet · 2004 · 10.1016/s0140-6736(04)16002-9

• Association of Breast Cancer DNA Methylation Profiles with Hormone Receptor Status and Response to Tamoxifen

  Cancer Research · 2004 · 10.1158/0008-5472.can-03-3852

• DNA Hypomethylation and Ovarian Cancer Biology

  Cancer Research · 2004 · 10.1158/0008-5472.can-04-0238

• DNA methylation in serum of breast cancer patients: an independent prognostic marker.

  PubMed · 2003

• hCDC4 gene mutations in endometrial cancer.

  PubMed · 2002

• DNA methylation and breast carcinogenesis

  Oncogene · 2002 · 10.1038/sj.onc.1205606

• Methylation and Silencing of the Retinoic Acid Receptor- 2 Gene in Breast Cancer

  JNCI Journal of the National Cancer Institute · 2000 · https://doi.org/10.1093/jnci/92.10.826

Current projects

No projects listed.