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Jan Johansson

Researcher Next ID · RN-034426

Researcher · Biochemistry, Genetics and Molecular Biology

Karolinska Institutet

Stockholm, Sweden

Accepting doctoral researchersFunding unknown
Works count
627
Citation count
22,484
H-index
77
i10-index
313

Research interests

Biochemistry, Genetics and Molecular Biology
Materials Science
Medicine
Neonatal Respiratory Health Research
Alzheimer's disease research and treatments
Silk-based biomaterials and applications
Protein Structure and Dynamics
Biochemical and Structural Characterization

Publications

  • Biomimetic spinning of artificial spider silk from a chimeric minispidroin

    Nature Chemical Biology · 2017 · 10.1038/nchembio.2269

  • Influence of Resin Composition on the Defect Formation in Alumina Manufactured by Stereolithography

    Materials · 2017 · 10.3390/ma10020138

  • Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation

    Nature Communications · 2016 · 10.1038/ncomms10948

  • Toward spinning artificial spider silk

    Nature Chemical Biology · 2015 · 10.1038/nchembio.1789

  • A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

    Nature Structural & Molecular Biology · 2015 · https://doi.org/10.1038/nsmb.2971

  • Carbonic Anhydrase Generates CO2 and H+ That Drive Spider Silk Formation Via Opposite Effects on the Terminal Domains

    PLoS Biology · 2014 · 10.1371/journal.pbio.1001921

  • Uropathogenic Escherichia coli Modulates Immune Responses and Its Curli Fimbriae Interact with the Antimicrobial Peptide LL-37

    PLoS Pathogens · 2010 · 10.1371/journal.ppat.1001010

  • RVX-208

    Journal of the American College of Cardiology · 2010 · 10.1016/j.jacc.2010.02.035

  • Self-assembly of spider silk proteins is controlled by a pH-sensitive relay

    Nature · 2010 · https://doi.org/10.1038/nature08962

  • Spider silk proteins: recent advances in recombinant production, structure–function relationships and biomedical applications

    Cellular and Molecular Life Sciences · 2010 · 10.1007/s00018-010-0462-z

  • Molecular basis for amyloid fibril formation and stability

    Proceedings of the National Academy of Sciences · 2005 · https://doi.org/10.1073/pnas.0406847102

  • Charge Attraction and β Propensity Are Necessary for Amyloid Fibril Formation from Tetrapeptides

    Journal of Biological Chemistry · 2002 · 10.1074/jbc.m205570200

  • Cardiovascular Status of Carriers of the Apolipoprotein A-I Milano Mutant

    Circulation · 2001 · 10.1161/01.cir.103.15.1949

  • Prediction of Amyloid Fibril-forming Proteins

    Journal of Biological Chemistry · 2001 · 10.1074/jbc.m010402200

  • Role of C-peptide in human physiology

    American Journal of Physiology-Endocrinology and Metabolism · 2000 · 10.1152/ajpendo.2000.278.5.e759

  • Conformation-dependent Antibacterial Activity of the Naturally Occurring Human Peptide LL-37

    Journal of Biological Chemistry · 1998 · https://doi.org/10.1074/jbc.273.6.3718

  • Effects of Recombinant Apolipoprotein A-I Milano on Aortic Atherosclerosis in Apolipoprotein E–Deficient Mice

    Circulation · 1998 · https://doi.org/10.1161/01.cir.97.8.780

  • Molecular Structures and Interactions of Pulmonary Surfactant Components

    European Journal of Biochemistry · 1997 · 10.1111/j.1432-1033.1997.00675.x

  • Arrest of -Amyloid Fibril Formation by a Pentapeptide Ligand

    Journal of Biological Chemistry · 1996 · https://doi.org/10.1074/jbc.271.15.8545

  • The proteins of the surfactant system

    European Respiratory Journal · 1994 · 10.1183/09031936.94.07020372

  • The effect of probucol on femoral atherosclerosis: The Probucol Quantitative Regression Swedish Trial (PQRST)

    The American Journal of Cardiology · 1994 · 10.1016/0002-9149(94)90579-7

  • The NMR Structure of the Pulmonary Surfactant-Associated Polypeptide SP-C in an Apolar Solvent Contains a Valyl-Rich .alpha.-Helix

    Biochemistry · 1994 · 10.1021/bi00185a042

  • Structure and orientation of the surfactant‐associated protein C in a lipid bilayer

    European Journal of Biochemistry · 1992 · 10.1111/j.1432-1033.1992.tb19848.x

  • High density lipoproteins and coronary atherosclerosis. A strong inverse relation with the largest particles is confined to normotriglyceridemic patients.

    Arteriosclerosis and Thrombosis A Journal of Vascular Biology · 1991 · 10.1161/01.atv.11.1.174

  • Hydrophobic surfactant-associated polypeptides: SP-C is a lipopeptide with two palmitoylated cysteine residues, whereas SP-B lacks covalently linked fatty acyl groups.

    Proceedings of the National Academy of Sciences · 1990 · 10.1073/pnas.87.8.2985

Current projects

    No projects listed.