Rolf Kiessling

Research interests

Publications

• Coexpressed Catalase Protects Chimeric Antigen Receptor–Redirected T Cells as well as Bystander Cells from Oxidative Stress–Induced Loss of Antitumor Activity

  The Journal of Immunology · 2015 · 10.4049/jimmunol.1401710

• Inhibition of Tumor-Derived Prostaglandin-E2 Blocks the Induction of Myeloid-Derived Suppressor Cells and Recovers Natural Killer Cell Activity

  Clinical Cancer Research · 2014 · 10.1158/1078-0432.ccr-14-0635

• Classification of current anticancer immunotherapies

  Oncotarget · 2014 · https://doi.org/10.18632/oncotarget.2998

• Immature Immunosuppressive CD14+HLA-DR−/low Cells in Melanoma Patients Are Stat3hi and Overexpress CD80, CD83, and DC-Sign

  Cancer Research · 2010 · 10.1158/0008-5472.can-09-3767

• Regulatory T Cells in Cancer

  Advances in cancer research · 2010 · 10.1016/s0065-230x(10)07003-x

• Primary Human Tumor Cells Expressing CD155 Impair Tumor Targeting by Down-Regulating DNAM-1 on NK Cells

  The Journal of Immunology · 2009 · 10.4049/jimmunol.0901226

• DNAX Accessory Molecule-1 Mediated Recognition of Freshly Isolated Ovarian Carcinoma by Resting Natural Killer Cells

  Cancer Research · 2007 · 10.1158/0008-5472.can-06-2264

• Heat-shock proteins as activators of the innate immune system

  Trends in Immunology · 2002 · https://doi.org/10.1016/s1471-4906(01)02168-8

• Circulating Heat Shock Protein 60 Is Associated With Early Cardiovascular Disease

  Hypertension · 2000 · 10.1161/01.hyp.36.2.303

• The human antimicrobial and chemotactic peptides LL-37 and α-defensins are expressed by specific lymphocyte and monocyte populations

  Blood · 2000 · https://doi.org/10.1182/blood.v96.9.3086

• Tumor-induced immune dysfunction

  Cancer Immunology Immunotherapy · 1999 · 10.1007/s002620050586

• Hydrogen peroxide secreted by tumor‐derived macrophages down‐modulates signal‐transducing zeta molecules and inhibits tumor‐specific T cell‐and natural killer cell‐mediated cytotoxicity

  European Journal of Immunology · 1996 · 10.1002/eji.1830260620

• Alterations in the signal‐transducing molecules of T cells and nk cells in colorectal tumor‐infiltrating, gut mucosal and peripheral lymphocytes: Correlation with the stage of the disease

  International Journal of Cancer · 1995 · 10.1002/ijc.2910610605

• Interleukin 10 pretreatment protects target cells from tumor- and allo-specific cytotoxic T cells and downregulates HLA class I expression.

  The Journal of Experimental Medicine · 1994 · 10.1084/jem.180.6.2371

• Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma.

  PubMed · 1993

• Selective expression of interleukin 10, interferon gamma, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies.

  Proceedings of the National Academy of Sciences · 1992 · 10.1073/pnas.89.16.7708

• Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy

  Nature · 1986 · https://doi.org/10.1038/319675a0

• "Anomalous" THY-1(+) killer cells in allogeneic and F1-anti-parental mixed leukocyte culture. Relation to natural killer cells and allospecific cytotoxic T lymphocytes

  The Journal of Experimental Medicine · 1982 · 10.1084/jem.156.2.385

• An Analysis of the Murine NK Cell as to Structure, Function and Biological Relevance

  Immunological Reviews · 1979 · 10.1111/j.1600-065x.1979.tb00270.x

• Target-effector interaction in the natural killer (NK) cell system. II. The isolation of NK cells and studies on the mechanism of killing.

  PubMed · 1978

• Role of non-conventional natural killer cells in resistance against syngeneic tumour cells in vivo

  Nature · 1977 · 10.1038/270609a0

• Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts

  European Journal of Immunology · 1977 · 10.1002/eji.1830070915

• Genetic variation of in vitro cytolytic activity and in vivo rejection potential of non‐immunized semi‐syngeneic mice against a mouse lymphoma line

  International Journal of Cancer · 1975 · https://doi.org/10.1002/ijc.2910150608

• „Natural” killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype

  European Journal of Immunology · 1975 · https://doi.org/10.1002/eji.1830050208

• „Natural” killer cells in the mouse. II. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer cell

  European Journal of Immunology · 1975 · https://doi.org/10.1002/eji.1830050209

Current projects

No projects listed.