Jonas Halfvarson

Research interests

Publications

• Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries

  Nature Genetics · 2023 · https://doi.org/10.1038/s41588-023-01384-0

• Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders

  Nature Genetics · 2021 · 10.1038/s41588-021-00950-8

• Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study

  The Lancet · 2020 · https://doi.org/10.1016/s0140-6736(19)32545-0

• Deep Remission at 1 Year Prevents Progression of Early Crohn’s Disease

  Gastroenterology · 2020 · https://doi.org/10.1053/j.gastro.2020.03.039

• IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-04365-8

• Natural disease course of Crohn’s disease during the first 5 years after diagnosis in a European population-based inception cohort: an Epi-IBD study

  Gut · 2018 · 10.1136/gutjnl-2017-315568

• Fine-mapping inflammatory bowel disease loci to single-variant resolution

  Nature · 2017 · 10.1038/nature22969

• Incidence and Treatment of Patients Diagnosed With Inflammatory Bowel Diseases at 60 Years or Older in Sweden

  Gastroenterology · 2017 · 10.1053/j.gastro.2017.10.034

• Dynamics of the human gut microbiome in inflammatory bowel disease

  Nature Microbiology · 2017 · https://doi.org/10.1038/nmicrobiol.2017.4

• Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

  Nature Genetics · 2016 · 10.1038/ng.3528

• Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease

  Nature Communications · 2016 · 10.1038/ncomms13507

• Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

  The Lancet · 2015 · https://doi.org/10.1016/s0140-6736(15)00465-1

• East–West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort

  Gut · 2013 · https://doi.org/10.1136/gutjnl-2013-304636

• Integrated Metagenomics/Metaproteomics Reveals Human Host-Microbiota Signatures of Crohn's Disease

  PLoS ONE · 2012 · 10.1371/journal.pone.0049138

• Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.764

• Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

  Nature Genetics · 2011 · 10.1038/ng.952

• Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.717

• Genome-wide association identifies multiple ulcerative colitis susceptibility loci

  Nature Genetics · 2010 · 10.1038/ng.549

• A Pyrosequencing Study in Twins Shows That Gastrointestinal Microbial Profiles Vary With Inflammatory Bowel Disease Phenotypes

  Gastroenterology · 2010 · https://doi.org/10.1053/j.gastro.2010.08.049

• Metabolomics Reveals Metabolic Biomarkers of Crohn's Disease

  PLoS ONE · 2009 · https://doi.org/10.1371/journal.pone.0006386

• DNA methylation profiles in monozygotic and dizygotic twins

  Nature Genetics · 2009 · 10.1038/ng.286

• Twin studies reveal specific imbalances in the mucosa-associated microbiota of patients with ileal Crohnʼs disease

  Inflammatory Bowel Diseases · 2008 · https://doi.org/10.1002/ibd.20783

• Shotgun metaproteomics of the human distal gut microbiota

  The ISME Journal · 2008 · https://doi.org/10.1038/ismej.2008.108

• Molecular analysis of the gut microbiota of identical twins with Crohn's disease

  The ISME Journal · 2008 · https://doi.org/10.1038/ismej.2008.37

• Inflammatory bowel disease in a Swedish twin cohort: a long-term follow-up of concordance and clinical characteristics

  Gastroenterology · 2003 · 10.1016/s0016-5085(03)00385-8

Current projects

No projects listed.