Alessandro Rambaldi

Research interests

Publications

• Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma

  New England Journal of Medicine · 2021 · https://doi.org/10.1056/nejmoa2024850

• Classification and Personalized Prognostic Assessment on the Basis of Clinical and Genomic Features in Myelodysplastic Syndromes

  Journal of Clinical Oncology · 2021 · https://doi.org/10.1200/jco.20.01659

• COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus

  Leukemia · 2020 · https://doi.org/10.1038/s41375-020-0959-x

• Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0400-z

• PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-018-0315-5

• Prognostic value of end-of-induction PET response after first-line immunochemotherapy for follicular lymphoma (GALLIUM): secondary analysis of a randomised, phase 3 trial

  The Lancet Oncology · 2018 · https://doi.org/10.1016/s1470-2045(18)30618-1

• Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia

  New England Journal of Medicine · 2017 · https://doi.org/10.1056/nejmoa1609783

• A clinical-molecular prognostic model to predict survival in patients with post polycythemia vera and post essential thrombocythemia myelofibrosis

  Leukemia · 2017 · https://doi.org/10.1038/leu.2017.169

• Complete Hematologic and Molecular Response in Adult Patients With Relapsed/Refractory Philadelphia Chromosome–Positive B-Precursor Acute Lymphoblastic Leukemia Following Treatment With Blinatumomab: Results From a Phase II, Single-Arm, Multicenter Study

  Journal of Clinical Oncology · 2017 · https://doi.org/10.1200/jco.2016.69.3531

• High Frequency and Poor Outcome of Philadelphia Chromosome–Like Acute Lymphoblastic Leukemia in Adults

  Journal of Clinical Oncology · 2017 · https://doi.org/10.1200/jco.2016.69.0073

• MIPSS70: Mutation-Enhanced International Prognostic Score System for Transplantation-Age Patients With Primary Myelofibrosis

  Journal of Clinical Oncology · 2017 · https://doi.org/10.1200/jco.2017.76.4886

• Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non–High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial

  Journal of Clinical Oncology · 2016 · https://doi.org/10.1200/jco.2016.67.1982

• Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia

  New England Journal of Medicine · 2015 · https://doi.org/10.1056/nejmoa1506583

• Indication and management of allogeneic stem cell transplantation in primary myelofibrosis: a consensus process by an EBMT/ELN international working group

  Leukemia · 2015 · https://doi.org/10.1038/leu.2015.233

• Practice-relevant revision of IPSET-thrombosis based on 1019 patients with WHO-defined essential thrombocythemia

  Blood Cancer Journal · 2015 · https://doi.org/10.1038/bcj.2015.94

• Long-term survival and blast transformation in molecularly annotated essential thrombocythemia, polycythemia vera, and myelofibrosis

  Blood · 2014 · https://doi.org/10.1182/blood-2014-05-579136

• Survival and prognosis among 1545 patients with contemporary polycythemia vera: an international study

  Leukemia · 2013 · https://doi.org/10.1038/leu.2013.163

• Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia

  New England Journal of Medicine · 2013 · https://doi.org/10.1056/nejmoa1300874

• Development and validation of an International Prognostic Score of thrombosis in World Health Organization–essential thrombocythemia (IPSET-thrombosis)

  Blood · 2012 · https://doi.org/10.1182/blood-2012-07-444067

• Myeloproliferative Neoplasm (MPN) Symptom Assessment Form Total Symptom Score: Prospective International Assessment of an Abbreviated Symptom Burden Scoring System Among Patients With MPNs

  Journal of Clinical Oncology · 2012 · https://doi.org/10.1200/jco.2012.42.3863

• Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype

  Blood · 2011 · https://doi.org/10.1182/blood-2011-07-365320

• The Myeloproliferative Neoplasm Symptom Assessment Form (MPN-SAF): International Prospective Validation and Reliability Trial in 402 patients

  Blood · 2011 · https://doi.org/10.1182/blood-2011-01-328955

• ABVD versus BEACOPP for Hodgkin's Lymphoma When High-Dose Salvage Is Planned

  New England Journal of Medicine · 2011 · https://doi.org/10.1056/nejmoa1100340

• Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: results of the AIDA-2000 trial of the GIMEMA Group

  Blood · 2010 · https://doi.org/10.1182/blood-2010-03-276196

• Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL)

  Blood · 2009 · https://doi.org/10.1182/blood-2008-11-185132

• Thrombosis in primary myelofibrosis: incidence and risk factors

  Blood · 2009 · https://doi.org/10.1182/blood-2009-08-238956

• Prospective identification of high-risk polycythemia vera patients based on JAK2V617F allele burden

  Leukemia · 2007 · https://doi.org/10.1038/sj.leu.2404854

• Clinical profile of homozygous JAK2 617V>F mutation in patients with polycythemia vera or essential thrombocythemia

  Blood · 2007 · https://doi.org/10.1182/blood-2006-12-064287

• Leukocytosis is a risk factor for thrombosis in essential thrombocythemia: interaction with treatment, standard risk factors, and Jak2 mutation status

  Blood · 2006 · https://doi.org/10.1182/blood-2006-09-046342

• CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: further regulation by CD55 and CD59

  Blood · 2001 · https://doi.org/10.1182/blood.v98.12.3383

• Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease

  Leukemia · 1999 · 10.1038/sj.leu.2401592

Current projects

No projects listed.