Giovanni Esposito

Research interests

Publications

• Immediate versus staged complete revascularisation in patients presenting with acute coronary syndrome and multivessel coronary disease (BIOVASC): a prospective, open-label, non-inferiority, randomised trial

  The Lancet · 2023 · https://doi.org/10.1016/s0140-6736(23)00351-3

• Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era

  European Heart Journal · 2020 · https://doi.org/10.1093/eurheartj/ehaa409

• Diagnostic Performance of In‐Procedure Angiography‐Derived Quantitative Flow Reserve Compared to Pressure‐Derived Fractional Flow Reserve: The FAVOR II Europe‐Japan Study

  Journal of the American Heart Association · 2018 · https://doi.org/10.1161/jaha.118.009603

• Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial

  The Lancet · 2018 · https://doi.org/10.1016/s0140-6736(18)31714-8

• Gut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis

  European Heart Journal · 2017 · https://doi.org/10.1093/eurheartj/ehx342

• Survival and Cardiovascular Outcomes of Patients With Secondary Mitral Regurgitation

  JAMA Cardiology · 2017 · https://doi.org/10.1001/jamacardio.2017.2976

• Continuum of Vasodilator Stress From Rest to Contrast Medium to Adenosine Hyperemia for Fractional Flow Reserve Assessment

  JACC: Cardiovascular Interventions · 2016 · https://doi.org/10.1016/j.jcin.2015.12.273

• Bivalirudin or Unfractionated Heparin in Acute Coronary Syndromes

  New England Journal of Medicine · 2015 · https://doi.org/10.1056/nejmoa1507854

• Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial

  The Lancet · 2015 · https://doi.org/10.1016/s0140-6736(15)60292-6

• SAT-TAVI (single antiplatelet therapy for TAVI) study: A pilot randomized study comparing double to single antiplatelet therapy for transcatheter aortic valve implantation

  International Journal of Cardiology · 2014 · https://doi.org/10.1016/j.ijcard.2014.04.170

• Circulating miR-29a, Among Other Up-Regulated MicroRNAs, Is the Only Biomarker for Both Hypertrophy and Fibrosis in Patients With Hypertrophic Cardiomyopathy

  Journal of the American College of Cardiology · 2013 · https://doi.org/10.1016/j.jacc.2013.09.041

• Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure

  Cardiovascular Research · 2008 · https://doi.org/10.1093/cvr/cvn215

• Efficient and cell specific knock-down of gene function in targeted C. elegans neurons

  Gene · 2007 · https://doi.org/10.1016/j.gene.2007.03.002

• Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation and female fertility

  Molecular and Cellular Endocrinology · 2007 · https://doi.org/10.1016/j.mce.2007.05.005

• Genetic Alterations That Inhibit In Vivo Pressure-Overload Hypertrophy Prevent Cardiac Dysfunction Despite Increased Wall Stress

  Circulation · 2002 · https://doi.org/10.1161/hc0102.101365

• Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A–deficient mice

  Journal of Clinical Investigation · 2001 · https://doi.org/10.1172/jci11273

• Gβγ-dependent Phosphoinositide 3-Kinase Activation in Hearts with in Vivo Pressure Overload Hypertrophy

  Journal of Biological Chemistry · 2000 · https://doi.org/10.1074/jbc.275.7.4693

• Activation of cAMP–PKA signaling in vivo inhibits smooth muscle cell proliferation induced by vascular injury

  Nature Medicine · 1997 · https://doi.org/10.1038/nm0797-775

• Detection of Chlamydia pneumoniae but not Helicobacter pylori in atherosclerotic plaques of aortic aneurysms

  Journal of Clinical Microbiology · 1996 · https://doi.org/10.1128/jcm.34.11.2766-2769.1996

• Inhibition of cellular ras prevents smooth muscle cell proliferation after vascular injury in vivo

  Nature Medicine · 1995 · https://doi.org/10.1038/nm0695-541

• Sternal wound infections and use of internal mammary artery grafts

  Journal of Thoracic and Cardiovascular Surgery · 1991 · https://doi.org/10.1016/s0022-5223(19)36516-x

Current projects

No projects listed.