Giacomo P. Comi

Research interests

Publications

• Onasemnogene abeparvovec gene therapy for symptomatic infantile-onset spinal muscular atrophy type 1 (STR1VE-EU): an open-label, single-arm, multicentre, phase 3 trial

  The Lancet Neurology · 2021 · https://doi.org/10.1016/s1474-4422(21)00251-9

• Neural Stem Cell Transplantation for Neurodegenerative Diseases

  International Journal of Molecular Sciences · 2020 · 10.3390/ijms21093103

• Neural Stem Cell Transplantation for Neurodegenerative Diseases

  International Journal of Molecular Sciences · 2020 · 10.3390/ijms21093103

• The Role of Mitochondria in Neurodegenerative Diseases: the Lesson from Alzheimer’s Disease and Parkinson’s Disease

  Molecular Neurobiology · 2020 · 10.1007/s12035-020-01926-1

• The Role of Mitochondria in Neurodegenerative Diseases: the Lesson from Alzheimer’s Disease and Parkinson’s Disease

  Molecular Neurobiology · 2020 · 10.1007/s12035-020-01926-1

• Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

  Nature Communications · 2017 · https://doi.org/10.1038/ncomms14774

• Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study

  Multiple Sclerosis Journal · 2015 · https://doi.org/10.1177/1352458514568827

• Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS

  Neuron · 2014 · https://doi.org/10.1016/j.neuron.2014.09.027

• Ataluren treatment of patients with nonsense mutation dystrophinopathy

  Muscle & Nerve · 2014 · https://doi.org/10.1002/mus.24332

• Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease

  Nature Genetics · 2013 · 10.1038/ng.2501

• Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease

  Nature Genetics · 2013 · 10.1038/ng.2501

• Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

  The Journal of Experimental Medicine · 2009 · 10.1084/jem.20082779

• Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

  The Journal of Experimental Medicine · 2009 · 10.1084/jem.20082779

• Reliability of the North Star Ambulatory Assessment in a multicentric setting

  Neuromuscular Disorders · 2009 · https://doi.org/10.1016/j.nmd.2009.06.368

• Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

  The Lancet · 2008 · https://doi.org/10.1016/s0140-6736(08)60918-6

• Autologous Transplantation of Muscle-Derived CD133+ Stem Cells in Duchenne Muscle Patients

  Cell Transplantation · 2007 · 10.3727/000000007783465064

• Autologous Transplantation of Muscle-Derived CD133+ Stem Cells in Duchenne Muscle Patients

  Cell Transplantation · 2007 · 10.3727/000000007783465064

• Identification of a Primitive Brain–Derived Neural Stem Cell Population Based on Aldehyde Dehydrogenase Activity

  Stem Cells · 2005 · 10.1634/stemcells.2005-0217

• Polyneuropathy in POEMS syndrome: role of angiogenic factors in the pathogenesis

  Brain · 2005 · 10.1093/brain/awh519

• Polyneuropathy in POEMS syndrome: role of angiogenic factors in the pathogenesis

  Brain · 2005 · 10.1093/brain/awh519

• Identification of a Primitive Brain–Derived Neural Stem Cell Population Based on Aldehyde Dehydrogenase Activity

  Stem Cells · 2005 · 10.1634/stemcells.2005-0217

• Mutations of mitochondrial DNA polymerase γA are a frequent cause of autosomal dominant or recessive progressive external ophthalmoplegia

  Annals of Neurology · 2002 · 10.1002/ana.10278

• Mutations of mitochondrial DNA polymerase γA are a frequent cause of autosomal dominant or recessive progressive external ophthalmoplegia

  Annals of Neurology · 2002 · 10.1002/ana.10278

• Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria

  Nature Genetics · 2001 · https://doi.org/10.1038/90058

• Role of Adenine Nucleotide Translocator 1 in mtDNA Maintenance

  Science · 2000 · 10.1126/science.289.5480.782

• Role of Adenine Nucleotide Translocator 1 in mtDNA Maintenance

  Science · 2000 · 10.1126/science.289.5480.782

• Cytochrome c Oxidase subunit I microdeletion in a patient with motor neuron disease

  Annals of Neurology · 1998 · 10.1002/ana.410430119

• Cytochrome c Oxidase subunit I microdeletion in a patient with motor neuron disease

  Annals of Neurology · 1998 · 10.1002/ana.410430119

Current projects

No projects listed.