Francisco J. Blanco

Research interests

Publications

• OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis

  Osteoarthritis and Cartilage · 2019 · https://doi.org/10.1016/j.joca.2019.06.011

• A Phase II Trial of Lutikizumab, an Anti–Interleukin‐1α/β Dual Variable Domain Immunoglobulin, in Knee Osteoarthritis Patients With Synovitis

  Arthritis & Rheumatology · 2019 · 10.1002/art.40840

• GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways

  Nature Communications · 2019 · https://doi.org/10.1038/s41467-019-12760-y

• 2018 update of the EULAR recommendations for the management of hand osteoarthritis

  Annals of the Rheumatic Diseases · 2018 · 10.1136/annrheumdis-2018-213826

• Mitochondrial DNA variation and the pathogenesis of osteoarthritis phenotypes

  Nature Reviews Rheumatology · 2018 · https://doi.org/10.1038/s41584-018-0001-0

• Ixekizumab for the treatment of patients with active psoriatic arthritis and an inadequate response to tumour necrosis factor inhibitors: results from the 24-week randomised, double-blind, placebo-controlled period of the SPIRIT-P2 phase 3 trial

  The Lancet · 2017 · 10.1016/s0140-6736(17)31429-0

• Intravenous administration of expanded allogeneic adipose-derived mesenchymal stem cells in refractory rheumatoid arthritis (Cx611): results of a multicentre, dose escalation, randomised, single-blind, placebo-controlled phase Ib/IIa clinical trial

  Annals of the Rheumatic Diseases · 2016 · 10.1136/annrheumdis-2015-208918

• Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis and current skin involvement: a phase III, randomised, controlled trial (PALACE 3)

  Annals of the Rheumatic Diseases · 2016 · 10.1136/annrheumdis-2015-207963

• Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use

  Osteoarthritis and Cartilage · 2015 · https://doi.org/10.1016/j.joca.2015.03.036

• Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

  Annals of the Rheumatic Diseases · 2015 · https://doi.org/10.1136/annrheumdis-2014-206792

• Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

  Nature Communications · 2015 · https://doi.org/10.1038/ncomms8146

• The role of mitochondria in osteoarthritis

  Nature Reviews Rheumatology · 2011 · 10.1038/nrrheum.2010.213

• Autophagy activation by rapamycin reduces severity of experimental osteoarthritis

  Annals of the Rheumatic Diseases · 2011 · 10.1136/annrheumdis-2011-200557

• Long‐term safety and efficacy of abatacept in children with juvenile idiopathic arthritis

  Arthritis & Rheumatism · 2010 · 10.1002/art.27431

• Autophagy is a protective mechanism in normal cartilage, and its aging‐related loss is linked with cell death and osteoarthritis

  Arthritis & Rheumatism · 2010 · https://doi.org/10.1002/art.27305

• Kidney tubular abnormalities in the absence of impaired glomerular function in HIV patients treated with tenofovir

  AIDS · 2009 · 10.1097/qad.0b013e3283262a64

• Mitochondrial Dysregulation of Osteoarthritic Human Articular Chondrocytes Analyzed by Proteomics

  Molecular & Cellular Proteomics · 2008 · https://doi.org/10.1074/mcp.m800292-mcp200

• Glucosamine sulfate in the treatment of knee osteoarthritis symptoms: A randomized, double‐blind, placebo‐controlled study using acetaminophen as a side comparator

  Arthritis & Rheumatism · 2007 · 10.1002/art.22371

• Cell Death and Apoptosis in Ostearthritic Cartilage

  Current Drug Targets · 2007 · https://doi.org/10.2174/138945007779940025

• Cytokines, tumor necrosis factor-α and interleukin-1β, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes

  Osteoarthritis and Cartilage · 2006 · 10.1016/j.joca.2006.01.005

• Mitochondrial dysfunction in osteoarthritis

  Mitochondrion · 2004 · https://doi.org/10.1016/j.mito.2004.07.022

• Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes

  Arthritis & Rheumatism · 2003 · 10.1002/art.10837

• Osteoarthritis chondrocytes die by apoptosis: A possible pathway for osteoarthritis pathology

  Arthritis & Rheumatism · 1998 · https://doi.org/10.1002/1529-0131(199802)41:2<284::aid-art12>3.0.co;2-t

• Chondrocyte apoptosis induced by nitric oxide.

  PubMed · 1995

• Growth factor responsiveness of human articular chondrocytes in aging and development

  Arthritis & Rheumatism · 1995 · https://doi.org/10.1002/art.1780380712

Current projects

No projects listed.