Paolo Nucíforo

Research interests

Publications

• The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology

  Nature Cancer · 2022 · https://doi.org/10.1038/s43018-022-00332-x

• A CT-based Radiomics Signature Is Associated with Response to Immune Checkpoint Inhibitors in Advanced Solid Tumors

  Radiology · 2021 · https://doi.org/10.1148/radiol.2021200928

• LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy

  Nature Communications · 2019 · https://doi.org/10.1038/s41467-019-10369-9

• HER2-Enriched Subtype and ERBB2 Expression in HER2-Positive Breast Cancer Treated with Dual HER2 Blockade

  JNCI Journal of the National Cancer Institute · 2019 · https://doi.org/10.1093/jnci/djz042

• RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer

  Annals of Oncology · 2018 · https://doi.org/10.1093/annonc/mdy099

• Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non–Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors

  Advances in Anatomic Pathology · 2017 · https://doi.org/10.1097/pap.0000000000000161

• Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research

  Advances in Anatomic Pathology · 2017 · https://doi.org/10.1097/pap.0000000000000162

• Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer

  Science · 2017 · https://doi.org/10.1126/science.aal5240

• Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non–Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourina

  Advances in Anatomic Pathology · 2017 · https://doi.org/10.1097/pap.0000000000000161

• Concordance of blood- and tumor-based detection of RAS mutations to guide anti-EGFR therapy in metastatic colorectal cancer

  Annals of Oncology · 2017 · https://doi.org/10.1093/annonc/mdx112

• mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

  Nature · 2017 · https://doi.org/10.1038/nature22964

• Immune-Related Gene Expression Profiling After PD-1 Blockade in Non–Small Cell Lung Carcinoma, Head and Neck Squamous Cell Carcinoma, and Melanoma

  Cancer Research · 2017 · https://doi.org/10.1158/0008-5472.can-16-3556

• Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab

  JAMA Oncology · 2015 · https://doi.org/10.1001/jamaoncol.2015.0830

• PIK3CA Mutations Are Associated With Decreased Benefit to Neoadjuvant Human Epidermal Growth Factor Receptor 2–Targeted Therapies in Breast Cancer

  Journal of Clinical Oncology · 2015 · https://doi.org/10.1200/jco.2014.55.2158

• Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration

  Annals of Oncology · 2015 · https://doi.org/10.1093/annonc/mdv161

• Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors

  Annals of Oncology · 2013 · https://doi.org/10.1093/annonc/mdt419

• NUMB controls p53 tumour suppressor activity

  Nature · 2008 · https://doi.org/10.1038/nature06412

• Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

  Genes & Development · 2006 · https://doi.org/10.1101/gad.406406

• Frequent Alterations in the Expression of Serine/Threonine Kinases in Human Cancers

  Cancer Research · 2006 · https://doi.org/10.1158/0008-5472.can-05-3489

• Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

  Nature · 2006 · https://doi.org/10.1038/nature05327

Current projects

No projects listed.