Antoni Castells

Research interests

Publications

• Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk

  The American Journal of Human Genetics · 2020 · https://doi.org/10.1016/j.ajhg.2020.07.006

• Circulating biomarkers for early detection and clinical management of colorectal cancer

  Molecular Aspects of Medicine · 2019 · https://doi.org/10.1016/j.mam.2019.06.002

• Transanal Total Mesorectal Excision for Rectal Cancer: Outcomes after 140 Patients

  Journal of the American College of Surgeons · 2015 · https://doi.org/10.1016/j.jamcollsurg.2015.03.046

• Transanal Total Mesorectal Excision in Rectal Cancer

  Annals of Surgery · 2014 · https://doi.org/10.1097/sla.0000000000000865

• Risk of Cancer in Cases of Suspected Lynch Syndrome Without Germline Mutation

  Gastroenterology · 2013 · https://doi.org/10.1053/j.gastro.2013.01.044

• A High Degree of LINE-1 Hypomethylation Is a Unique Feature of Early-Onset Colorectal Cancer

  PLoS ONE · 2012 · https://doi.org/10.1371/journal.pone.0045357

• EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness

  Cellular and Molecular Life Sciences · 2012 · https://doi.org/10.1007/s00018-012-1122-2

• Colonoscopy versus Fecal Immunochemical Testing in Colorectal-Cancer Screening

  New England Journal of Medicine · 2012 · https://doi.org/10.1056/nejmoa1108895

• Identification of Lynch Syndrome Among Patients With Colorectal Cancer

  JAMA · 2012 · https://doi.org/10.1001/jama.2012.13088

• β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness

  Proceedings of the National Academy of Sciences · 2011 · https://doi.org/10.1073/pnas.1108977108

• LIN28B Promotes Colon Cancer Progression and Metastasis

  Cancer Research · 2011 · https://doi.org/10.1158/0008-5472.can-10-4637

• ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1

  Oncogene · 2010 · https://doi.org/10.1038/onc.2010.102

• A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

  Nature Genetics · 2008 · https://doi.org/10.1038/ng.111

• The Long-term Results of a Randomized Clinical Trial of Laparoscopy-assisted Versus Open Surgery for Colon Cancer

  Annals of Surgery · 2008 · https://doi.org/10.1097/sla.0b013e31816a9d65

• SMAD4 mutations found in unselected HHT patients

  Journal of Medical Genetics · 2006 · https://doi.org/10.1136/jmg.2006.041517

• Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

  Proceedings of the National Academy of Sciences · 2006 · https://doi.org/10.1073/pnas.0600645103

• Postoperative Surveillance in Patients With Colorectal Cancer Who Have Undergone Curative Resection: A Prospective, Multicenter, Randomized, Controlled Trial

  Journal of Clinical Oncology · 2005 · https://doi.org/10.1200/jco.2005.02.0826

• Preoperative Staging and Tumor Resectability Assessment of Pancreatic Cancer: Prospective Study Comparing Endoscopic Ultrasonography, Helical Computed Tomography, Magnetic Resonance Imaging, and Angiography

  The American Journal of Gastroenterology · 2004 · https://doi.org/10.1111/j.1572-0241.2004.04087.x

• The regional allocation of infrastructure investment: The role of equity, efficiency and political factors

  European Economic Review · 2003 · https://doi.org/10.1016/j.euroecorev.2003.07.002

• Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial

  The Lancet · 2002 · https://doi.org/10.1016/s0140-6736(02)09290-5

• Natural History of Untreated Nonsurgical Hepatocellular Carcinoma: Rationale for the Design and Evaluation of Therapeutic Trials

  Hepatology · 1999 · https://doi.org/10.1002/hep.510290145

• Transarterial embolization versus symptomatic treatment in patients with advanced hepatocellular carcinoma: Results of a randomized, controlled trial in a single institution

  Hepatology · 1998 · https://doi.org/10.1002/hep.510270617

• Liver transplantation for small hepatocellular carcinoma: The tumor-node-metastasis classification does not have prognostic power

  Hepatology · 1998 · https://doi.org/10.1002/hep.510270616

• Surgical resection of hepatocellular carcinoma in cirrhotic patients: Prognostic value of preoperative portal pressure

  Gastroenterology · 1996 · https://doi.org/10.1016/s0016-5085(96)70070-7

• Treatment of small hepatocellular carcinoma in cirrhotic patients: A cohort study comparing surgical resection and percutaneous ethanol injection

  Hepatology · 1993 · https://doi.org/10.1002/hep.1840180517

Current projects

No projects listed.