Pedro Romero

Research interests

Publications

• Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity

  Nature Immunology · 2021 · https://doi.org/10.1038/s41590-021-00940-2

• Metabolic and epigenetic regulation of T-cell exhaustion

  Nature Metabolism · 2020 · https://doi.org/10.1038/s42255-020-00280-9

• The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance

  Cell stem cell · 2019 · https://doi.org/10.1016/j.stem.2019.02.012

• Navigating metabolic pathways to enhance antitumour immunity and immunotherapy

  Nature Reviews Clinical Oncology · 2019 · https://doi.org/10.1038/s41571-019-0203-7

• Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients

  Proceedings of the National Academy of Sciences · 2015 · https://doi.org/10.1073/pnas.1417320112

• The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis

  Nature Communications · 2014 · https://doi.org/10.1038/ncomms6621

• Interactions between Siglec-7/9 receptors and ligands influence NK cell–dependent tumor immunosurveillance

  Journal of Clinical Investigation · 2014 · https://doi.org/10.1172/jci65899

• Hypoxia-Inducible miR-210 Regulates the Susceptibility of Tumor Cells to Lysis by Cytotoxic T Cells

  Cancer Research · 2012 · https://doi.org/10.1158/0008-5472.can-12-1383

• Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients

  Journal of Clinical Investigation · 2011 · https://doi.org/10.1172/jci46102

• Blocking Hypoxia-Induced Autophagy in Tumors Restores Cytotoxic T-Cell Activity and Promotes Regression

  Cancer Research · 2011 · https://doi.org/10.1158/0008-5472.can-11-1094

• Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

  Immunity · 2011 · https://doi.org/10.1016/j.immuni.2011.02.006

• BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination

  Journal of Clinical Investigation · 2010 · https://doi.org/10.1172/jci40070

• Human natural Treg microRNA signature: Role of microRNA‐31 and microRNA‐21 in FOXP3 expression

  European Journal of Immunology · 2009 · https://doi.org/10.1002/eji.200838509

• The Cooperative Induction of Hypoxia-Inducible Factor-1α and STAT3 during Hypoxia Induced an Impairment of Tumor Susceptibility to CTL-Mediated Cell Lysis

  The Journal of Immunology · 2009 · https://doi.org/10.4049/jimmunol.0800854

• Tumour immunity: effector response to tumour and role of the microenvironment

  The Lancet · 2008 · https://doi.org/10.1016/s0140-6736(08)60241-x

• TLR3 Deficiency in Patients with Herpes Simplex Encephalitis

  Science · 2007 · https://doi.org/10.1126/science.1139522

• Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909

  Journal of Clinical Investigation · 2005 · https://doi.org/10.1172/jci23373

• BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth

  The Journal of Experimental Medicine · 1999 · https://doi.org/10.1084/jem.189.11.1747

• High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals

  The Journal of Experimental Medicine · 1999 · https://doi.org/10.1084/jem.190.5.705

• Ex Vivo Staining of Metastatic Lymph Nodes by Class I Major Histocompatibility Complex Tetramers Reveals High Numbers of Antigen-experienced Tumor-specific Cytolytic T Lymphocytes

  The Journal of Experimental Medicine · 1998 · https://doi.org/10.1084/jem.188.9.1641

• Enhanced Generation of Specific Tumor-Reactive CTL In Vitro by Selected Melan-A/MART-1 Immunodominant Peptide Analogues

  The Journal of Immunology · 1998 · https://doi.org/10.4049/jimmunol.160.4.1750

• High Frequency of Skin-homing Melanocyte-specific Cytotoxic T Lymphocytes in Autoimmune Vitiligo

  The Journal of Experimental Medicine · 1998 · https://doi.org/10.1084/jem.188.6.1203

• Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape

  Science · 1996 · https://doi.org/10.1126/science.274.5291.1363

• Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes.

  The Journal of Experimental Medicine · 1994 · https://doi.org/10.1084/jem.179.3.921

• Induction of protective immunity against experimental infection with malaria using synthetic peptides

  Nature · 1987 · https://doi.org/10.1038/328629a0

Current projects

No projects listed.