Ernest Giralt

Research interests

Publications

• Chemical Approaches to the Synthesis of Peptides and Proteins

  Journal · 2020 · https://doi.org/10.1201/9781003069225

• Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons

  Proceedings of the National Academy of Sciences · 2018 · https://doi.org/10.1073/pnas.1804198115

• Cell-Penetrating Peptides: Design Strategies beyond Primary Structure and Amphipathicity

  Molecules · 2017 · https://doi.org/10.3390/molecules22111929

• Measuring the Spin‐Polarization Power of a Single Chiral Molecule

  Small · 2016 · 10.1002/smll.201602519

• Blood–brain barrier shuttle peptides: an emerging paradigm for brain delivery

  Chemical Society Reviews · 2016 · https://doi.org/10.1039/c6cs00076b

• Three Valuable Peptides from Bee and Wasp Venoms for Therapeutic and Biotechnological Use: Melittin, Apamin and Mastoparan

  Toxins · 2015 · https://doi.org/10.3390/toxins7041126

• Modulating protein–protein interactions: the potential of peptides

  Chemical Communications · 2014 · https://doi.org/10.1039/c4cc08565e

• Delivery of gold nanoparticles to the brain by conjugation with a peptide that recognizes the transferrin receptor

  Biomaterials · 2012 · https://doi.org/10.1016/j.biomaterials.2012.06.063

• Perspectives on NMR in drug discovery: a technique comes of age

  Nature Reviews Drug Discovery · 2008 · https://doi.org/10.1038/nrd2606

• Mechanism of action of and resistance to quinolones

  Microbial Biotechnology · 2008 · https://doi.org/10.1111/j.1751-7915.2008.00063.x

• Proline-rich, amphipathic cell-penetrating peptides

  Advanced Drug Delivery Reviews · 2007 · https://doi.org/10.1016/j.addr.2007.09.012

• Mechanistic aspects of CPP-mediated intracellular drug delivery: Relevance of CPP self-assembly

  Biochimica et Biophysica Acta (BBA) - Biomembranes · 2006 · https://doi.org/10.1016/j.bbamem.2006.01.006

• Nanoparticle-Mediated Local and Remote Manipulation of Protein Aggregation

  Nano Letters · 2005 · https://doi.org/10.1021/nl0516862

• Molecular recycling within amyloid fibrils

  Nature · 2005 · https://doi.org/10.1038/nature03986

• Peptide and Amide Bond-Containing Dendrimers

  Chemical Reviews · 2005 · https://doi.org/10.1021/cr030449l

• Potential Peptide Carriers: Amphipathic Proline‐Rich Peptides Derived from the N‐Terminal Domain of γ‐Zein

  Angewandte Chemie International Edition · 2004 · 10.1002/anie.200352540

• Atropisomerism, biphenyls and the Suzuki coupling: peptide antibiotics

  Chemical Society Reviews · 2001 · https://doi.org/10.1039/b001971m

• Prodigiosin from the supernatant of Serratia marcescens induces apoptosis in haematopoietic cancer cell lines

  British Journal of Pharmacology · 2000 · 10.1038/sj.bjp.0703614

• Use of Alloc-amino acids in solid-phase peptide synthesis. Tandem deprotection-coupling reactions using neutral conditions

  Tetrahedron Letters · 1997 · 10.1016/s0040-4039(97)01690-0

• A large-scale evaluation of peptide vaccines against foot-and-mouth disease: lack of solid protection in cattle and isolation of escape mutants

  Journal of Virology · 1997 · https://doi.org/10.1128/jvi.71.4.2606-2614.1997

• Anion Helicates: Double Strand Helical Self-Assembly of Chiral Bicyclic Guanidinium Dimers and Tetramers around Sulfate Templates

  Journal of the American Chemical Society · 1996 · https://doi.org/10.1021/ja953243d

• Structure of the major antigenic loop of foot‐and‐mouth disease virus complexed with a neutralizing antibody: direct involvement of the Arg‐Gly‐Asp motif in the interaction.

  The EMBO Journal · 1995 · 10.1002/j.1460-2075.1995.tb07158.x

• Association between double mutation in gyrA gene of ciprofloxacin-resistant clinical isolates of Escherichia coli and MICs

  Antimicrobial Agents and Chemotherapy · 1994 · https://doi.org/10.1128/aac.38.10.2477

• Convergent solid-phase peptide synthesis

  Tetrahedron · 1993 · https://doi.org/10.1016/s0040-4020(01)81800-7

• A single amino acid substitution affects multiple overlapping epitopes in the major antigenic site of foot-and-mouth disease virus of serotype C

  Journal of General Virology · 1990 · 10.1099/0022-1317-71-3-629

Current projects

No projects listed.