Akira Suzuki

Research interests

Publications

• Cross‐Coupling Reactions Of Organoboranes: An Easy Way To Construct CC Bonds (Nobel Lecture)

  Angewandte Chemie International Edition · 2011 · https://doi.org/10.1002/anie.201101379

• Kreuzkupplungen von Organoboranen: ein einfacher Weg zum Aufbau von C‐C‐Bindungen (Nobel‐Aufsatz)

  Angewandte Chemie · 2011 · 10.1002/ange.201101379

• Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

  Cancer Research · 2011 · https://doi.org/10.1158/0008-5472.can-11-1021

• Biological functions of asparagine synthetase in plants

  Plant Science · 2010 · 10.1016/j.plantsci.2010.04.010

• Nitrogen uptake, assimilation and remobilization in plants: challenges for sustainable and productive agriculture

  Annals of Botany · 2010 · https://doi.org/10.1093/aob/mcq028

• Mammalian phosphoinositide kinases and phosphatases

  Progress in Lipid Research · 2009 · 10.1016/j.plipres.2009.06.001

• Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1

  Nature Cell Biology · 2006 · 10.1038/ncb1515

• Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN

  Nature · 2006 · https://doi.org/10.1038/nature04925

• Carbon–carbon bonding made easy

  Chemical Communications · 2005 · 10.1039/b507375h

• The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis

  Genes & Development · 2005 · 10.1101/gad.1308805

• Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

  Journal of Clinical Investigation · 2004 · 10.1172/jci20513

• Notch–RBP-J signaling is involved in cell fate determination of marginal zone B cells

  Nature Immunology · 2002 · 10.1038/ni793

• Regulation of Myocardial Contractility and Cell Size by Distinct PI3K-PTEN Signaling Pathways

  Cell · 2002 · 10.1016/s0092-8674(02)00969-8

• Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

  Nature Genetics · 2001 · 10.1038/ng782

• T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

  Immunity · 2001 · 10.1016/s1074-7613(01)00134-0

• High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice.

  PubMed · 2000

• Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration

  Science · 2000 · 10.1126/science.287.5455.1040

• Musashi1: An Evolutionally Conserved Marker for CNS Progenitor Cells Including Neural Stem Cells

  Developmental Neuroscience · 2000 · 10.1159/000017435

• Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

  Cell · 1998 · https://doi.org/10.1016/s0092-8674(00)81780-8

• High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

  Current Biology · 1998 · 10.1016/s0960-9822(07)00488-5

• Brca2 is required for embryonic cellular proliferation in the mouse.

  Genes & Development · 1997 · 10.1101/gad.11.10.1242

• New synthetic transformations via organoboron compounds

  Pure and Applied Chemistry · 1994 · 10.1351/pac199466020213

• Synthesis of Sterically Hindered Biaryls via the Palladium-Catalyzed Cross-Coupling Reaction of Arylboronic Acids or their Esters with Haloarenes

  Synlett · 1992 · 10.1055/s-1992-21315

• Synthetic studies via the cross-coupling reaction of organoboron derivatives with organic halides

  Pure and Applied Chemistry · 1991 · 10.1351/pac199163030419

• Organoborates in new synthetic reactions

  Accounts of Chemical Research · 1982 · 10.1021/ar00078a003

Current projects

No projects listed.