Mamoru Watanabe

Research interests

Publications

• The cost of inflammatory bowel disease in high-income settings: a Lancet Gastroenterology & Hepatology Commission

  ˜The œLancet. Gastroenterology & hepatology · 2023 · https://doi.org/10.1016/s2468-1253(23)00003-1

• Filgotinib as induction and maintenance therapy for ulcerative colitis (SELECTION): a phase 2b/3 double-blind, randomised, placebo-controlled trial

  The Lancet · 2021 · https://doi.org/10.1016/s0140-6736(21)00666-8

• Evidence-based clinical practice guidelines for inflammatory bowel disease 2020

  Journal of Gastroenterology · 2021 · https://doi.org/10.1007/s00535-021-01784-1

• Development and Validation of a Deep Neural Network for Accurate Evaluation of Endoscopic Images From Patients With Ulcerative Colitis

  Gastroenterology · 2020 · 10.1053/j.gastro.2020.02.012

• Evidence-based clinical practice guidelines for inflammatory bowel disease

  Journal of Gastroenterology · 2018 · https://doi.org/10.1007/s00535-018-1439-1

• Efficacy of Indigo Naturalis in a Multicenter Randomized Controlled Trial of Patients With Ulcerative Colitis

  Gastroenterology · 2017 · https://doi.org/10.1053/j.gastro.2017.11.024

• Efficacy of Indigo Naturalis in a Multicenter Randomized Controlled Trial of Patients With Ulcerative Colitis

  Gastroenterology · 2017 · https://doi.org/10.1053/j.gastro.2017.11.024

• YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration

  Cell stem cell · 2017 · https://doi.org/10.1016/j.stem.2017.11.001

• Evidence-based clinical practice guidelines for liver cirrhosis 2015

  Journal of Gastroenterology · 2016 · 10.1007/s00535-016-1216-y

• Bowel Ultrasonography in the Management of Crohnʼs Disease. A Review with Recommendations of an International Panel of Experts

  Inflammatory Bowel Diseases · 2016 · https://doi.org/10.1097/mib.0000000000000706

• Adalimumab Monotherapy and a Combination with Azathioprine for Crohn’s Disease: A Prospective, Randomized Trial

  Journal of Crohn s and Colitis · 2016 · https://doi.org/10.1093/ecco-jcc/jjw152

• Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015

  Journal of Gastroenterology · 2016 · 10.1007/s00535-016-1227-8

• Leucine-rich Alpha-2 Glycoprotein is a Serum Biomarker of Mucosal Healing in Ulcerative Colitis

  Journal of Crohn s and Colitis · 2016 · https://doi.org/10.1093/ecco-jcc/jjw132

• Evidence-based clinical practice guidelines for cholelithiasis 2016

  Journal of Gastroenterology · 2016 · 10.1007/s00535-016-1289-7

• α-fetoprotein levels after interferon therapy and risk of hepatocarcinogenesis in chronic hepatitis C

  Hepatology · 2013 · 10.1002/hep.26442

• Transplantation of Expanded Fetal Intestinal Progenitors Contributes to Colon Regeneration after Injury

  Cell stem cell · 2013 · https://doi.org/10.1016/j.stem.2013.09.015

• Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell

  Nature Medicine · 2012 · 10.1038/nm.2695

• The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD With the European Crohn's and Colitis Organization: When to Start, When to Stop, Which Drug to Choose, and How to Predict Response?

  The American Journal of Gastroenterology · 2010 · 10.1038/ajg.2010.392

• Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis

  American Journal of Physiology-Gastrointestinal and Liver Physiology · 2009 · https://doi.org/10.1152/ajpgi.00071.2008

• Prevalence of ulcerative colitis and Crohn’s disease in Japan

  Journal of Gastroenterology · 2009 · 10.1007/s00535-009-0057-3

• Inducible expression of microRNA-194 is regulated by HNF-1α during intestinal epithelial cell differentiation

  RNA · 2008 · https://doi.org/10.1261/rna.810208

• Requirement of Notch activation during regeneration of the intestinal epithelia

  American Journal of Physiology-Gastrointestinal and Liver Physiology · 2008 · https://doi.org/10.1152/ajpgi.90225.2008

• MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis

  Journal of Gastroenterology · 2005 · https://doi.org/10.1007/s00535-004-1492-9

• CD4+CD25bright T Cells in Human Intestinal Lamina Propria as Regulatory Cells

  The Journal of Immunology · 2004 · https://doi.org/10.4049/jimmunol.173.5.3119

• Interferon Regulatory Factor 1 (IRF-1) and IRF-2 Distinctively Up-Regulate Gene Expression and Production of Interleukin-7 in Human Intestinal Epithelial Cells

  Molecular and Cellular Biology · 2004 · https://doi.org/10.1128/mcb.24.14.6298-6310.2004

• Inhibition of intracellular hepatitis C virus replication by synthetic and vector‐derived small interfering RNAs

  EMBO Reports · 2003 · 10.1038/sj.embor.embor840

• Regulation of Murine Inflammatory Bowel Disease by CD25+ and CD25− CD4+ Glucocorticoid-Induced TNF Receptor Family-Related Gene+ Regulatory T Cells

  The Journal of Immunology · 2003 · https://doi.org/10.4049/jimmunol.171.2.708

• Blockade of B7-H1 Suppresses the Development of Chronic Intestinal Inflammation

  The Journal of Immunology · 2003 · https://doi.org/10.4049/jimmunol.171.8.4156

• Damaged epithelia regenerated by bone marrow–derived cells in the human gastrointestinal tract

  Nature Medicine · 2002 · https://doi.org/10.1038/nm755

• Embryoid-body cells derived from a mouse embryonic stem cell line show differentiation into functional hepatocytes

  Hepatology · 2002 · 10.1053/jhep.2002.34136

• Layer-by-Layer Assembly of Titania Nanosheet/Polycation Composite Films

  Chemistry of Materials · 2001 · 10.1021/cm010478h

• Macrophage-derived IL-18–mediated intestinal inflammation in the murine model of Crohn's disease

  Gastroenterology · 2001 · https://doi.org/10.1053/gast.2001.28021

• Osmotic Swelling to Exfoliation. Exceptionally High Degrees of Hydration of a Layered Titanate

  Journal of the American Chemical Society · 1998 · 10.1021/ja974262l

• A Mixed Alkali Metal Titanate with the Lepidocrocite-like Layered Structure. Preparation, Crystal Structure, Protonic Form, and Acid−Base Intercalation Properties

  Chemistry of Materials · 1998 · 10.1021/cm980535f

• Semiconductor Nanosheet Crystallites of Quasi-TiO 2 and Their Optical Properties

  The Journal of Physical Chemistry B · 1997 · 10.1021/jp9727658

• Macromolecule-like Aspects for a Colloidal Suspension of an Exfoliated Titanate. Pairwise Association of Nanosheets and Dynamic Reassembling Process Initiated from It

  Journal of the American Chemical Society · 1996 · 10.1021/ja960073b

• Preparation and Acid-Base Properties of a Protonated Titanate with the Lepidocrocite-like Layer Structure

  Chemistry of Materials · 1995 · 10.1021/cm00053a029

Current projects

No projects listed.