Mitsuaki Isobe

Research interests

Publications

• Multidisciplinary Cardiac Rehabilitation and Long-Term Prognosis in Patients With Heart Failure

  Circulation Heart Failure · 2020 · 10.1161/circheartfailure.119.006798

• JCS 2020 Guideline on Diagnosis and Treatment of Cardiac Amyloidosis

  Circulation Journal · 2020 · https://doi.org/10.1253/circj.cj-20-0110

• JCS 2016 Guideline on Diagnosis and Treatment of Cardiac Sarcoidosis ― Digest Version ―

  Circulation Journal · 2019 · https://doi.org/10.1253/circj.cj-19-0508

• JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure ― Digest Version ―

  Circulation Journal · 2019 · https://doi.org/10.1253/circj.cj-19-0342

• An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

  Journal of Clinical Investigation · 2018 · 10.1172/jci122035

• Efficacy and safety of tocilizumab in patients with refractory Takayasu arteritis: results from a randomised, double-blind, placebo-controlled, phase 3 trial in Japan (the TAKT study)

  Annals of the Rheumatic Diseases · 2017 · 10.1136/annrheumdis-2017-211878

• Regulation of autophagy by Beclin 1 in the heart

  Journal of Molecular and Cellular Cardiology · 2015 · 10.1016/j.yjmcc.2015.10.032

• Integrating Genetic, Transcriptional, and Functional Analyses to Identify 5 Novel Genes for Atrial Fibrillation

  Circulation · 2014 · https://doi.org/10.1161/circulationaha.114.009892

• Takayasu arteritis revisited: Current diagnosis and treatment

  International Journal of Cardiology · 2013 · 10.1016/j.ijcard.2013.01.022

• Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

  Nature Medicine · 2013 · https://doi.org/10.1038/nm.3322

• Two Susceptibility Loci to Takayasu Arteritis Reveal a Synergistic Role of the IL12B and HLA-B Regions in a Japanese Population

  The American Journal of Human Genetics · 2013 · 10.1016/j.ajhg.2013.05.024

• Role of FDG PET-CT in Takayasu Arteritis

  JACC. Cardiovascular imaging · 2012 · 10.1016/j.jcmg.2012.01.013

• Improved Prognosis of Takayasu Arteritis Over the Past Decade

  Circulation Journal · 2012 · 10.1253/circj.cj-11-1108

• In vivo critical fibrous cap thickness for rupture-prone coronary plaques assessed by optical coherence tomography

  European Heart Journal · 2011 · https://doi.org/10.1093/eurheartj/ehq518

• A Global In Vivo Drosophila RNAi Screen Identifies NOT3 as a Conserved Regulator of Heart Function

  Cell · 2010 · 10.1016/j.cell.2010.02.023

• Induction of premature senescence in cardiomyocytes by doxorubicin as a novel mechanism of myocardial damage

  Aging Cell · 2007 · 10.1111/j.1474-9726.2007.00358.x

• Progesterone Regulates Cardiac Repolarization Through a Nongenomic Pathway

  Circulation · 2007 · 10.1161/circulationaha.107.702407

• Clinical Implications of Reconnection Between the Left Atrium and Isolated Pulmonary Veins Provoked by Adenosine Triphosphate after Extensive Encircling Pulmonary Vein Isolation

  Journal of Cardiovascular Electrophysiology · 2007 · 10.1111/j.1540-8167.2006.00753.x

• Electrocardiographic and electrophysiologic characteristics of ventricular tachycardia originating within the pulmonary artery

  Journal of the American College of Cardiology · 2005 · 10.1016/j.jacc.2004.10.071

• Nitric oxide inhibits myocardial apoptosis by preventing caspase-3 activity via S-nitrosylation

  Journal of Molecular and Cellular Cardiology · 2004 · 10.1016/j.yjmcc.2004.10.012

• National Survey of Fulminant Myocarditis in Japan

  Circulation Journal · 2002 · 10.1253/circj.66.133

• Prognostic determinants of long-term survival in Japanese patients with cardiac sarcoidosis treated with prednisone

  The American Journal of Cardiology · 2001 · https://doi.org/10.1016/s0002-9149(01)01978-6

• Cardiac sarcoidosis: Diagnostic, prognostic, and therapeutic considerations

  Cardiovascular Drugs and Therapy · 1996 · 10.1007/bf00050989

• Precursor polyprotein for multiple neuropeptides secreted from the suboesophageal ganglion of the silkworm Bombyx mori: characterization of the cDNA encoding the diapause hormone precursor and identification of additional peptides.

  Proceedings of the National Academy of Sciences · 1993 · 10.1073/pnas.90.8.3251

• Specific Acceptance of Cardiac Allograft After Treatment with Antibodies to ICAM-1 and LFA-1

  Science · 1992 · https://doi.org/10.1126/science.1347662

Current projects

No projects listed.