Eiji Oki

Research interests

Publications

• ctDNA-based molecular residual disease and survival in resectable colorectal cancer

  Nature Medicine · 2024 · https://doi.org/10.1038/s41591-024-03254-6

• Molecular residual disease and efficacy of adjuvant chemotherapy in patients with colorectal cancer

  Nature Medicine · 2023 · https://doi.org/10.1038/s41591-022-02115-4

• Panitumumab vs Bevacizumab Added to Standard First-line Chemotherapy and Overall Survival Among Patients With RAS Wild-type, Left-Sided Metastatic Colorectal Cancer

  JAMA · 2023 · https://doi.org/10.1001/jama.2023.4428

• CIRCULATE‐Japan: Circulating tumor DNA–guided adaptive platform trials to refine adjuvant therapy for colorectal cancer

  Cancer Science · 2021 · https://doi.org/10.1111/cas.14926

• Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies

  Nature Medicine · 2020 · https://doi.org/10.1038/s41591-020-1063-5

• Effect of duration of adjuvant chemotherapy for patients with stage III colon cancer (IDEA collaboration): final results from a prospective, pooled analysis of six randomised, phase 3 trials

  The Lancet Oncology · 2020 · https://doi.org/10.1016/s1470-2045(20)30527-1

• Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition

  Nature Medicine · 2018 · https://doi.org/10.1038/s41591-018-0022-x

• Assessment of Sarcopenia as a Predictor of Poor Outcomes After Esophagectomy in Elderly Patients With Esophageal Cancer

  Annals of Surgery · 2017 · https://doi.org/10.1097/sla.0000000000002252

• Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer Cells

  Gastroenterology · 2017 · https://doi.org/10.1053/j.gastro.2017.03.046

• Sarcopenia is an independent predictor of complications after colorectal cancer surgery

  Surgery Today · 2017 · https://doi.org/10.1007/s00595-017-1564-0

• Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution

  PLoS Genetics · 2016 · https://doi.org/10.1371/journal.pgen.1005778

• Prognostic Nutritional Index Predicts Severe Complications, Recurrence, and Poor Prognosis in Patients With Colorectal Cancer Undergoing Primary Tumor Resection

  Diseases of the Colon & Rectum · 2015 · https://doi.org/10.1097/dcr.0000000000000458

• Deregulation of the Akt Pathway in Human Cancer

  Current Cancer Drug Targets · 2008 · https://doi.org/10.2174/156800908783497140

• Advances in esophageal cancer surgery in Japan: An analysis of 1000 consecutive patients treated at a single institute

  Surgery · 2008 · https://doi.org/10.1016/j.surg.2007.12.007

• Validation of HB-EGF and amphiregulin as targets for human cancer therapy

  Biochemical and Biophysical Research Communications · 2007 · https://doi.org/10.1016/j.bbrc.2007.11.015

• Activation of PI3K/Akt signaling and hormone resistance in breast cancer

  Breast Cancer · 2006 · https://doi.org/10.2325/jbcs.13.137

• Clinical Significance of Heparin-Binding Epidermal Growth Factor–Like Growth Factor and A Disintegrin and Metalloprotease 17 Expression in Human Ovarian Cancer

  Clinical Cancer Research · 2005 · https://doi.org/10.1158/1078-0432.ccr-04-1426

• Akt is frequently activated in HER2/neu-positive breast cancers and associated with poor prognosis among hormone-treated patients

  International Journal of Cancer · 2005 · https://doi.org/10.1002/ijc.21358

• Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer

  International Journal of Cancer · 2005 · https://doi.org/10.1002/ijc.21170

• Overexpression of theMTA1 gene in gastrointestinal carcinomas: Correlation with invasion and metastasis

  International Journal of Cancer · 1997 · https://doi.org/10.1002/(sici)1097-0215(19970822)74:4<459::aid-ijc18>3.0.co;2-4

Current projects

No projects listed.