Yasuhito Tanaka

Research interests

Publications

• Epidermal growth factor receptor is a host-entry cofactor triggering hepatitis B virus internalization

  Proceedings of the National Academy of Sciences · 2019 · 10.1073/pnas.1811064116

• Gut Dysbiosis Associated With Hepatitis C Virus Infection

  Clinical Infectious Diseases · 2018 · 10.1093/cid/ciy205

• The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus

  Immunity · 2014 · 10.1016/j.immuni.2014.12.016

• Interleukin-1 and Tumor Necrosis Factor-α Trigger Restriction of Hepatitis B Virus Infection via a Cytidine Deaminase Activation-induced Cytidine Deaminase (AID)

  Journal of Biological Chemistry · 2013 · 10.1074/jbc.m113.501122

• A serum “sweet-doughnut” protein facilitates fibrosis evaluation and therapy assessment in patients with viral hepatitis

  Scientific Reports · 2013 · 10.1038/srep01065

• Cyclosporin A and Its Analogs Inhibit Hepatitis B Virus Entry Into Cultured Hepatocytes Through Targeting a Membrane Transporter, Sodium Taurocholate Cotransporting Polypeptide (NTCP)

  Hepatology · 2013 · 10.1002/hep.26982

• Consumption of n-3 Fatty Acids and Fish Reduces Risk of Hepatocellular Carcinoma

  Gastroenterology · 2012 · 10.1053/j.gastro.2012.02.018

• Geographical and genetic diversity of the human hepatitis B virus

  Hepatology Research · 2010 · 10.1111/j.1872-034x.2009.00601.x

• Hepatic ISG Expression Is Associated With Genetic Variation in Interleukin 28B and the Outcome of IFN Therapy for Chronic Hepatitis C

  Gastroenterology · 2010 · 10.1053/j.gastro.2010.04.049

• Ferrous Polycrystalline Shape-Memory Alloy Showing Huge Superelasticity

  Science · 2010 · https://doi.org/10.1126/science.1183169

• A Genetic Variant of Hepatitis B Virus Divergent from Known Human and Ape Genotypes Isolated from a Japanese Patient and Provisionally Assigned to New Genotype J

  Journal of Virology · 2009 · 10.1128/jvi.00462-09

• Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.449

• Independent risk factors and predictive score for the development of hepatocellular carcinoma in chronic hepatitis B

  Journal of Hepatology · 2008 · https://doi.org/10.1016/j.jhep.2008.07.023

• Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas

  Hepatology Research · 2007 · 10.1111/j.1872-034x.2007.00141.x

• Risk for hepatocellular carcinoma with respect to hepatitis B virus genotypes B/C, specific mutations of enhancer II/core promoter/precore regions and HBV DNA levels

  Gut · 2007 · 10.1136/gut.2007.119859

• Influence of hepatitis B virus genotypes on the intra‐ and extracellular expression of viral DNA and antigens†‡

  Hepatology · 2006 · 10.1002/hep.21345

• Influence of genotypes and precore mutations on fulminant or chronic outcome of acute hepatitis B virus infection

  Hepatology · 2006 · 10.1002/hep.21249

• A new subtype (subgenotype) Ac (A3) of hepatitis B virus and recombination between genotypes A and E in Cameroon

  Journal of General Virology · 2005 · 10.1099/vir.0.80922-0

• Genes for direct methylation of glycine provide high levels of glycinebetaine and abiotic-stress tolerance in Synechococcus and Arabidopsis

  Proceedings of the National Academy of Sciences · 2005 · 10.1073/pnas.0409017102

• Glucose Toxicity in β-Cells: Type 2 Diabetes, Good Radicals Gone Bad, and the Glutathione Connection

  Diabetes · 2003 · https://doi.org/10.2337/diabetes.52.3.581

• A role for glutathione peroxidase in protecting pancreatic β cells against oxidative stress in a model of glucose toxicity

  Proceedings of the National Academy of Sciences · 2002 · 10.1073/pnas.192445199

• A comparison of the molecular clock of hepatitis C virus in the United States and Japan predicts that hepatocellular carcinoma incidence in the United States will increase over the next two decades

  Proceedings of the National Academy of Sciences · 2002 · 10.1073/pnas.242608099

• Genomic and Molecular Evolutionary Analysis of a Newly Identified Infectious Agent (SEN Virus) and Its Relationship to the TT Virus Family

  The Journal of Infectious Diseases · 2001 · 10.1086/318091

• Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants

  Proceedings of the National Academy of Sciences · 1999 · https://doi.org/10.1073/pnas.96.19.10857

• Hepatitis B virus genotype assignment using restriction fragment length polymorphism patterns

  FEBS Letters · 1999 · 10.1016/s0014-5793(99)00471-8

Current projects

No projects listed.