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Hirohisa Saito

Researcher Next ID · RN-035904

Researcher · Immunology and Microbiology

National Center For Child Health and Development

Tokyo, Japan

Accepting doctoral researchersFunding unknown
Works count
1,183
Citation count
34,216
H-index
94
i10-index
461

Research interests

Immunology and Microbiology
Medicine
Asthma and respiratory diseases
Mast cells and histamine
Food Allergy and Anaphylaxis Research
Allergic Rhinitis and Sensitization
IL-33, ST2, and ILC Pathways

Publications

  • Mast cells as sources of cytokines, chemokines, and growth factors

    Immunological Reviews · 2018 · https://doi.org/10.1111/imr.12634

  • Two-step egg introduction for prevention of egg allergy in high-risk infants with eczema (PETIT): a randomised, double-blind, placebo-controlled trial

    The Lancet · 2016 · 10.1016/s0140-6736(16)31418-0

  • Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants

    Journal of Allergy and Clinical Immunology · 2015 · 10.1016/j.jaci.2015.06.001

  • An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers

    Immunity · 2015 · 10.1016/j.immuni.2015.06.021

  • The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

    Nature Immunology · 2015 · 10.1038/ni.3085

  • The Interleukin-33-p38 Kinase Axis Confers Memory T Helper 2 Cell Pathogenicity in the Airway

    Immunity · 2015 · 10.1016/j.immuni.2015.01.016

  • Application of moisturizer to neonates prevents development of atopic dermatitis

    Journal of Allergy and Clinical Immunology · 2014 · 10.1016/j.jaci.2014.07.060

  • Rationale and study design of the Japan environment and children’s study (JECS)

    BMC Public Health · 2014 · https://doi.org/10.1186/1471-2458-14-25

  • Present state of Japanese cedar pollinosis: The national affliction

    Journal of Allergy and Clinical Immunology · 2013 · 10.1016/j.jaci.2013.11.002

  • IL-33 Mediates Inflammatory Responses in Human Lung Tissue Cells

    The Journal of Immunology · 2010 · 10.4049/jimmunol.0903818

  • Antimicrobial Peptides Human β-Defensins and Cathelicidin LL-37 Induce the Secretion of a Pruritogenic Cytokine IL-31 by Human Mast Cells

    The Journal of Immunology · 2010 · 10.4049/jimmunol.0900712

  • IL-33 is a crucial amplifier of innate rather than acquired immunity

    Proceedings of the National Academy of Sciences · 2010 · 10.1073/pnas.1003059107

  • Intra-articular Injected Synovial Stem Cells Differentiate into Meniscal Cells Directly and Promote Meniscal Regeneration Without Mobilization to Distant Organs in Rat Massive Meniscal Defect

    Stem Cells · 2009 · 10.1634/stemcells.2008-0616

  • Th17 and Allergy

    Allergology International · 2008 · 10.2332/allergolint.r-07-160

  • IL-33 can promote survival, adhesion and cytokine production in human mast cells

    Laboratory Investigation · 2007 · 10.1038/labinvest.3700663

  • IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcεRI signals

    Journal of Leukocyte Biology · 2007 · 10.1189/jlb.0407200

  • SOCS-3 regulates onset and maintenance of TH2-mediated allergic responses

    Nature Medicine · 2003 · 10.1038/nm896

  • Selective growth of human mast cells induced by Steel factor, IL-6, and prostaglandin E2 from cord blood mononuclear cells

    The Journal of Immunology · 1996 · 10.4049/jimmunol.157.1.343

  • Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation.

    PubMed · 1993

  • Coding visual images of objects in the inferotemporal cortex of the macaque monkey

    Journal of Neurophysiology · 1991 · https://doi.org/10.1152/jn.1991.66.1.170

  • A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen.

    The Journal of Experimental Medicine · 1988 · 10.1084/jem.168.5.1523

  • Selective differentiation and proliferation of hematopoietic cells induced by recombinant human interleukins.

    Proceedings of the National Academy of Sciences · 1988 · 10.1073/pnas.85.7.2288

  • Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.

    The Journal of Experimental Medicine · 1987 · 10.1084/jem.166.5.1548

  • Integration of direction signals of image motion in the superior temporal sulcus of the macaque monkey

    Journal of Neuroscience · 1986 · https://doi.org/10.1523/jneurosci.06-01-00145.1986

  • Analysis of local and wide-field movements in the superior temporal visual areas of the macaque monkey

    Journal of Neuroscience · 1986 · https://doi.org/10.1523/jneurosci.06-01-00134.1986

Current projects

    No projects listed.