Yoshito Itoh

Research interests

Publications

• Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 2020

  Journal of Gastroenterology · 2021 · 10.1007/s00535-021-01796-x

• CheckMate 040 cohort 5: A phase I/II study of nivolumab in patients with advanced hepatocellular carcinoma and Child-Pugh B cirrhosis

  Journal of Hepatology · 2021 · 10.1016/j.jhep.2021.04.047

• The epidemiology of NAFLD and lean NAFLD in Japan: a meta-analysis with individual and forecasting analysis, 1995–2040

  Hepatology International · 2021 · 10.1007/s12072-021-10143-4

• Survival of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Influenza Virus on Human Skin: Importance of Hand Hygiene in Coronavirus Disease 2019 (COVID-19)

  Clinical Infectious Diseases · 2020 · 10.1093/cid/ciaa1517

• Green tea polyphenol (epigallocatechin-3-gallate) improves gut dysbiosis and serum bile acids dysregulation in high-fat diet-fed mice

  Journal of Clinical Biochemistry and Nutrition · 2019 · 10.3164/jcbn.18-116

• Differences in gut microbiota associated with age, sex, and stool consistency in healthy Japanese subjects

  Journal of Gastroenterology · 2018 · https://doi.org/10.1007/s00535-018-1488-5

• Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers

  PLoS ONE · 2018 · 10.1371/journal.pone.0185490

• Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection

  Gastroenterology · 2017 · 10.1053/j.gastro.2017.01.041

• The JAK/STAT pathway is involved in the upregulation of PD-L1 expression in pancreatic cancer cell lines

  Oncology Reports · 2017 · 10.3892/or.2017.5399

• p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells

  Cancer Cell · 2016 · https://doi.org/10.1016/j.ccell.2016.04.006

• Phase I clinical trial of autologous NK cell therapy using novel expansion method in patients with advanced digestive cancer

  Journal of Translational Medicine · 2015 · https://doi.org/10.1186/s12967-015-0632-8

• Prevalence of and risk factors for non-alcoholic fatty liver disease in a non-obese Japanese population, 2011–2012

  Journal of Gastroenterology · 2014 · 10.1007/s00535-014-0948-9

• Type 2 diabetes mellitus is associated with the fibrosis severity in patients with nonalcoholic fatty liver disease in a large retrospective cohort of Japanese patients

  Journal of Gastroenterology · 2013 · 10.1007/s00535-013-0911-1

• Genome-Wide Association Study Confirming Association of HLA-DP with Protection against Chronic Hepatitis B and Viral Clearance in Japanese and Korean

  PLoS ONE · 2012 · 10.1371/journal.pone.0039175

• Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population

  BMC Gastroenterology · 2012 · https://doi.org/10.1186/1471-230x-12-2

• Nonalcoholic steatohepatitis and increased risk of chronic kidney disease

  Metabolism · 2010 · 10.1016/j.metabol.2010.07.022

• Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease

  Journal of Gastroenterology · 2010 · 10.1007/s00535-010-0291-8

• Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease

  Hepatology Research · 2008 · 10.1111/j.1872-034x.2008.00464.x

• The Severity of Ultrasonographic Findings in Nonalcoholic Fatty Liver Disease Reflects the Metabolic Syndrome and Visceral Fat Accumulation

  The American Journal of Gastroenterology · 2007 · https://doi.org/10.1111/j.1572-0241.2007.01526.x

• Fenofibrate, a peroxisome proliferator‐activated receptor α agonist, reduces hepatic steatosis and lipid peroxidation in fatty liver Shionogi mice with hereditary fatty liver

  Liver International · 2006 · 10.1111/j.1478-3231.2006.01265.x

• A green tea polyphenol, epigalocatechin-3-gallate, induces apoptosis of human hepatocellular carcinoma, possibly through inhibition of Bcl-2 family proteins

  Journal of Hepatology · 2005 · 10.1016/j.jhep.2005.11.045

• PPARα ligands activate antioxidant enzymes and suppress hepatic fibrosis in rats

  Biochemical and Biophysical Research Communications · 2004 · 10.1016/j.bbrc.2004.09.110

• Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma after a sustained response to interferon therapy

  Cancer · 2004 · 10.1002/cncr.20537

• Side effects of high-dose interferon therapy for chronic hepatitis C

  Journal of Hepatology · 1996 · 10.1016/s0168-8278(96)80113-9

• A synthetic peptide vaccine involving the product of the pre-S(2) region of hepatitis B virus DNA: protective efficacy in chimpanzees.

  Proceedings of the National Academy of Sciences · 1986 · 10.1073/pnas.83.23.9174

Current projects

No projects listed.