Hiroshi Yamazaki

Research interests

Publications

• Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population

  Gastroenterology · 2016 · https://doi.org/10.1053/j.gastro.2016.01.035

• Roles of NADPH-P450 Reductase and Apo- and Holo-Cytochrome b5 on Xenobiotic Oxidations Catalyzed by 12 Recombinant Human Cytochrome P450s Expressed in Membranes of Escherichia coli

  Protein Expression and Purification · 2002 · https://doi.org/10.1006/prep.2001.1578

• Inhibitory effects of amiodarone and its N ‐deethylated metabolite on human cytochrome P450 activities: Prediction of in vivo drug interactions

  British Journal of Clinical Pharmacology · 2000 · https://doi.org/10.1046/j.1365-2125.2000.00134.x

• Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes

  Archives of Toxicology · 1999 · https://doi.org/10.1007/s002040050588

• Activation and detoxication of aflatoxin B1

  Mutation research. Fundamental and molecular mechanisms of mutagenesis · 1998 · https://doi.org/10.1016/s0027-5107(97)00289-3

• Selectivity of Polycyclic Inhibitors for Human Cytochrome P450s 1A1, 1A2, and 1B1

  Chemical Research in Toxicology · 1998 · https://doi.org/10.1021/tx980090+

• Roles of Cytochromes P450 1A2 and 3A4 in the Oxidation of Estradiol and Estrone in Human Liver Microsomes

  Chemical Research in Toxicology · 1998 · https://doi.org/10.1021/tx970217f

• Comparative Studies on the Catalytic Roles of Cytochrome P450 2C9 and Its Cys- and Leu-Variants in the Oxidation of Warfarin, Flurbiprofen, and Diclofenac by Human Liver Microsomes

  Biochemical Pharmacology · 1998 · https://doi.org/10.1016/s0006-2952(98)00133-6

• Progesterone and Testosterone Hydroxylation by Cytochromes P450 2C19, 2C9, and 3A4 in Human Liver Microsomes

  Archives of Biochemistry and Biophysics · 1997 · https://doi.org/10.1006/abbi.1997.0302

• Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.

  PubMed · 1996

• Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.

  PubMed · 1996

• Lack of Electron Transfer from Cytochrome b5 in Stimulation of Catalytic Activities of Cytochrome P450 3A4

  Journal of Biological Chemistry · 1996 · https://doi.org/10.1074/jbc.271.44.27438

• Oxidation of Aflatoxin B1 by Bacterial Recombinant Human Cytochrome P450 Enzymes

  Chemical Research in Toxicology · 1995 · https://doi.org/10.1021/tx00044a006

• Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

  Journal of Pharmacology and Experimental Therapeutics · 1994 · https://doi.org/10.1016/s0022-3565(25)22379-5

• Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens.

  Molecular Pharmacology · 1992 · https://doi.org/10.1016/s0026-895x(25)09132-1

• Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N -nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

  Carcinogenesis · 1992 · https://doi.org/10.1093/carcin/13.10.1789

Current projects

No projects listed.