Hideo Nakamura

Research interests

Publications

• Effects of Surgery With Salvage Stereotactic Radiosurgery Versus Surgery With Whole-Brain Radiation Therapy in Patients With One to Four Brain Metastases (JCOG0504): A Phase III, Noninferiority, Randomized Controlled Trial

  Journal of Clinical Oncology · 2018 · https://doi.org/10.1200/jco.2018.78.6186

• Prognostic relevance of genetic alterations in diffuse lower-grade gliomas

  Neuro-Oncology · 2017 · https://doi.org/10.1093/neuonc/nox132

• Intertumoral Heterogeneity within Medulloblastoma Subgroups

  Cancer Cell · 2017 · https://doi.org/10.1016/j.ccell.2017.05.005

• A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas

  Acta Neuropathologica Communications · 2016 · https://doi.org/10.1186/s40478-016-0351-2

• Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

  Cancer Cell · 2016 · https://doi.org/10.1016/j.ccell.2016.11.003

• Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis

  The Lancet Oncology · 2015 · https://doi.org/10.1016/s1470-2045(15)70114-2

• Mutational landscape and clonal architecture in grade II and III gliomas

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3273

• Novel somatic and germline mutations in intracranial germ cell tumours

  Nature · 2014 · https://doi.org/10.1038/nature13296

• CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity

  Acta Neuropathologica · 2014 · https://doi.org/10.1007/s00401-014-1291-1

• Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis

  The Lancet Oncology · 2012 · https://doi.org/10.1016/s1470-2045(12)70257-7

• Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint

  Free Radical Biology and Medicine · 2012 · https://doi.org/10.1016/j.freeradbiomed.2012.04.033

• p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia

  Journal of Molecular and Cellular Cardiology · 2011 · https://doi.org/10.1016/j.yjmcc.2011.10.008

• Grading Astrocytic Tumors by Using Apparent Diffusion Coefficient Parameters: Superiority of a One- versus Two-Parameter Pilot Method

  Radiology · 2009 · https://doi.org/10.1148/radiol.2513080899

• Malignant Supratentorial Astrocytoma Treated with Postoperative Radiation Therapy: Prognostic Value of Pretreatment Quantitative Diffusion-weighted MR Imaging

  Radiology · 2007 · https://doi.org/10.1148/radiol.2432060450

• Synthesis of solid superacids and their activities for reactions of alkanes

  Catalysis Today · 2003 · https://doi.org/10.1016/s0920-5861(03)00098-1

• Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme.

  PubMed · 2003

• Roles of Rho-associated Kinase in Cytokinesis; Mutations in Rho-associated Kinase Phosphorylation Sites Impair Cytokinetic Segregation of Glial Filaments

  The Journal of Cell Biology · 1998 · https://doi.org/10.1083/jcb.143.5.1249

• Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

  Nature Genetics · 1998 · https://doi.org/10.1038/ng0198-65

• TLP1: A Gene Encoding a Protein Component of Mammalian Telomerase Is a Novel Member of WD Repeats Family

  Cell · 1997 · https://doi.org/10.1016/s0092-8674(00)81933-9

• The biologically active constituents of Ganoderma lucidum (Fr.) Karst. Histamine release-inhibitory triterpenes.

  Chemical and Pharmaceutical Bulletin · 1985 · https://doi.org/10.1248/cpb.33.1367

• Studies on heterocyclic compounds. 6. Synthesis and analgesic and antiinflammatory activities of 3,4-dimethylpyrano[2,3-c]pyrazol-6-one derivatives

  Journal of Medicinal Chemistry · 1984 · https://doi.org/10.1021/jm00370a020

Current projects

No projects listed.