Xiao‐Jun Huang

Research interests

Publications

• The consensus from The Chinese Society of Hematology on indications, conditioning regimens and donor selection for allogeneic hematopoietic stem cell transplantation: 2021 update

  Journal of Hematology & Oncology · 2021 · https://doi.org/10.1186/s13045-021-01159-2

• Treatment and unmet needs in steroid-refractory acute graft-versus-host disease

  Leukemia · 2020 · https://doi.org/10.1038/s41375-020-0804-2

• Sorafenib maintenance in patients with FLT3-ITD acute myeloid leukaemia undergoing allogeneic haematopoietic stem-cell transplantation: an open-label, multicentre, randomised phase 3 trial

  The Lancet Oncology · 2020 · https://doi.org/10.1016/s1470-2045(20)30455-1

• Low-dose post-transplant cyclophosphamide and anti-thymocyte globulin as an effective strategy for GVHD prevention in haploidentical patients

  Journal of Hematology & Oncology · 2019 · https://doi.org/10.1186/s13045-019-0781-y

• The European Society for Blood and Marrow Transplantation (EBMT) consensus recommendations for donor selection in haploidentical hematopoietic cell transplantation

  Bone Marrow Transplantation · 2019 · https://doi.org/10.1038/s41409-019-0499-z

• Apoptotic Caspases Suppress Type I Interferon Production via the Cleavage of cGAS, MAVS, and IRF3

  Molecular Cell · 2019 · https://doi.org/10.1016/j.molcel.2019.02.013

• The European Society for Blood and Marrow Transplantation (EBMT) Consensus Guidelines for the Detection and Treatment of Donor-specific Anti-HLA Antibodies (DSA) in Haploidentical Hematopoietic Cell Transplantation

  Bone Marrow Transplantation · 2018 · https://doi.org/10.1038/s41409-017-0062-8

• Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses

  Immunity · 2018 · https://doi.org/10.1016/j.immuni.2018.03.017

• The consensus on indications, conditioning regimen, and donor selection of allogeneic hematopoietic cell transplantation for hematological diseases in China—recommendations from the Chinese Society of Hematology

  Journal of Hematology & Oncology · 2018 · https://doi.org/10.1186/s13045-018-0564-x

• Haploidentical allograft is superior to matched sibling donor allograft in eradicating pre-transplantation minimal residual disease of AML patients as determined by multiparameter flow cytometry: a retrospective and prospective analysis

  Journal of Hematology & Oncology · 2017 · https://doi.org/10.1186/s13045-017-0502-3

• Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant

  Journal of Hematology & Oncology · 2017 · https://doi.org/10.1186/s13045-017-0398-y

• Haploidentical versus Matched-Sibling Transplant in Adults with Philadelphia-Negative High-Risk Acute Lymphoblastic Leukemia: A Biologically Phase III Randomized Study

  Clinical Cancer Research · 2016 · https://doi.org/10.1158/1078-0432.ccr-15-2335

• Donor-specific anti-human leukocyte antigen antibodies were associated with primary graft failure after unmanipulated haploidentical blood and marrow transplantation: a prospective study with randomly assigned training and validation sets

  Journal of Hematology & Oncology · 2015 · https://doi.org/10.1186/s13045-015-0182-9

• Haploidentical vs identical-sibling transplant for AML in remission: a multicenter, prospective study

  Blood · 2015 · https://doi.org/10.1182/blood-2015-02-627786

• CD147 reprograms fatty acid metabolism in hepatocellular carcinoma cells through Akt/mTOR/SREBP1c and P38/PPARα pathways

  Journal of Hepatology · 2015 · https://doi.org/10.1016/j.jhep.2015.07.039

• Who is the best donor for a related HLA haplotype-mismatched transplant?

  Blood · 2014 · https://doi.org/10.1182/blood-2014-03-563130

• A distinct glucose metabolism signature of acute myeloid leukemia with prognostic value

  Blood · 2014 · https://doi.org/10.1182/blood-2014-02-554204

• Homoharringtonine-based induction regimens for patients with de-novo acute myeloid leukaemia: a multicentre, open-label, randomised, controlled phase 3 trial

  The Lancet Oncology · 2013 · https://doi.org/10.1016/s1470-2045(13)70152-9

• Oral Tetra-Arsenic Tetra-Sulfide Formula Versus Intravenous Arsenic Trioxide As First-Line Treatment of Acute Promyelocytic Leukemia: A Multicenter Randomized Controlled Trial

  Journal of Clinical Oncology · 2013 · https://doi.org/10.1200/jco.2013.48.8312

• MRD-directed risk stratification treatment may improve outcomes of t(8;21) AML in the first complete remission: results from the AML05 multicenter trial

  Blood · 2013 · https://doi.org/10.1182/blood-2012-11-468348

• Risk stratification–directed donor lymphocyte infusion could reduce relapse of standard-risk acute leukemia patients after allogeneic hematopoietic stem cell transplantation

  Blood · 2012 · https://doi.org/10.1182/blood-2011-09-380386

• Long‐term follow‐up of haploidentical hematopoietic stem cell transplantation without in vitro T cell depletion for the treatment of leukemia

  Cancer · 2012 · https://doi.org/10.1002/cncr.27761

• An oncogenic role of miR-142-3p in human T-cell acute lymphoblastic leukemia (T-ALL) by targeting glucocorticoid receptor-α and cAMP/PKA pathways

  Leukemia · 2011 · https://doi.org/10.1038/leu.2011.273

• Superior Graft-versus-Leukemia Effect Associated with Transplantation of Haploidentical Compared with HLA-Identical Sibling Donor Grafts for High-Risk Acute Leukemia: An Historic Comparison

  Transplantation and Cellular Therapy · 2010 · https://doi.org/10.1016/j.bbmt.2010.08.023

• Treatment of Acute Leukemia with Unmanipulated HLA-Mismatched/Haploidentical Blood and Bone Marrow Transplantation

  Transplantation and Cellular Therapy · 2009 · https://doi.org/10.1016/j.bbmt.2008.11.025

• CD34+CD38+CD19+ as well as CD34+CD38−CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL

  Leukemia · 2008 · https://doi.org/10.1038/leu.2008.83

• A2A adenosine receptor protects tumors from antitumor T cells

  Proceedings of the National Academy of Sciences · 2006 · https://doi.org/10.1073/pnas.0605251103

• Conditioning including antithymocyte globulin followed by unmanipulated HLA-mismatched/haploidentical blood and marrow transplantation can achieve comparable outcomes with HLA-identical sibling transplantation

  Blood · 2005 · https://doi.org/10.1182/blood-2005-05-2146

• Steroid-receptor fusion of the human immunodeficiency virus type 1 Rev transactivator: mapping cryptic functions of the arginine-rich motif.

  Proceedings of the National Academy of Sciences · 1990 · https://doi.org/10.1073/pnas.87.19.7787

Current projects

No projects listed.