Hong Zhang

Research interests

Publications

• Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula

  Journal of Ethnopharmacology · 2023 · https://doi.org/10.1016/j.jep.2023.116306

• Tenecteplase versus alteplase in acute ischaemic cerebrovascular events (TRACE-2): a phase 3, multicentre, open-label, randomised controlled, non-inferiority trial

  The Lancet · 2023 · https://doi.org/10.1016/s0140-6736(22)02600-9

• Phase Separation in Membrane Biology: The Interplay between Membrane-Bound Organelles and Membraneless Condensates

  Developmental Cell · 2020 · 10.1016/j.devcel.2020.06.033

• Isorhamnetin: A review of pharmacological effects

  Biomedicine & Pharmacotherapy · 2020 · https://doi.org/10.1016/j.biopha.2020.110301

• Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases

  Science China Life Sciences · 2020 · 10.1007/s11427-020-1702-x

• A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects

  Biomedicine & Pharmacotherapy · 2020 · https://doi.org/10.1016/j.biopha.2020.110505

• Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy

  New England Journal of Medicine · 2019 · https://doi.org/10.1056/nejmoa1811744

• Fabrication of magnetic bentonite/carboxymethyl chitosan/sodium alginate hydrogel beads for Cu (II) adsorption

  International Journal of Biological Macromolecules · 2019 · https://doi.org/10.1016/j.ijbiomac.2019.05.185

• Reduced default mode network functional connectivity in patients with recurrent major depressive disorder

  Proceedings of the National Academy of Sciences · 2019 · https://doi.org/10.1073/pnas.1900390116

• Prevalence, risk factors, and management of asthma in China: a national cross-sectional study

  The Lancet · 2019 · https://doi.org/10.1016/s0140-6736(19)31147-x

• LINC01133 as ceRNA inhibits gastric cancer progression by sponging miR-106a-3p to regulate APC expression and the Wnt/β-catenin pathway

  Molecular Cancer · 2018 · https://doi.org/10.1186/s12943-018-0874-1

• Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study

  The Lancet · 2018 · https://doi.org/10.1016/s0140-6736(18)30841-9

• Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

  Nature Medicine · 2018 · https://doi.org/10.1038/s41591-018-0275-4

• Autophagosome maturation: An epic journey from the ER to lysosomes

  The Journal of Cell Biology · 2018 · 10.1083/jcb.201810099

• A new switching-delayed-PSO-based optimized SVM algorithm for diagnosis of Alzheimer’s disease

  Neurocomputing · 2018 · https://doi.org/10.1016/j.neucom.2018.09.001

• Oxford Classification of IgA nephropathy 2016: an update from the IgA Nephropathy Classification Working Group

  Kidney International · 2017 · https://doi.org/10.1016/j.kint.2017.02.003

• Effect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy

  JAMA · 2017 · https://doi.org/10.1001/jama.2017.9362

• Hollow Co3O4 Nanosphere Embedded in Carbon Arrays for Stable and Flexible Solid‐State Zinc–Air Batteries

  Advanced Materials · 2017 · https://doi.org/10.1002/adma.201704117

• Portulaca oleracea L.: A Review of Phytochemistry and Pharmacological Effects

  BioMed Research International · 2015 · https://doi.org/10.1155/2015/925631

• Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction

  Nature Chemical Biology · 2014 · https://doi.org/10.1038/nchembio.1427

• T-Cell Profile in Adipose Tissue Is Associated With Insulin Resistance and Systemic Inflammation in Humans

  Arteriosclerosis Thrombosis and Vascular Biology · 2014 · https://doi.org/10.1161/atvbaha.114.304636

• A novel rice C2H2-type zinc finger protein, ZFP36, is a key player involved in abscisic acid-induced antioxidant defence and oxidative stress tolerance in rice

  Journal of Experimental Botany · 2014 · https://doi.org/10.1093/jxb/eru313

• Puerarin: A Review of Pharmacological Effects

  Phytotherapy Research · 2013 · https://doi.org/10.1002/ptr.5083

• Polydatin: A review of pharmacology and pharmacokinetics

  Pharmaceutical Biology · 2013 · https://doi.org/10.3109/13880209.2013.792849

• Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

  Science · 2012 · 10.1126/science.1222804

• Nitric Oxide Mediates Brassinosteroid-Induced ABA Biosynthesis Involved in Oxidative Stress Tolerance in Maize Leaves

  Plant and Cell Physiology · 2010 · https://doi.org/10.1093/pcp/pcq187

• C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms

  Cell · 2010 · 10.1016/j.cell.2010.04.034

• The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification

  Kidney International · 2009 · https://doi.org/10.1038/ki.2009.243

• The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility

  Kidney International · 2009 · https://doi.org/10.1038/ki.2009.168

• Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships

  Journal of Medicinal Chemistry · 2008 · https://doi.org/10.1021/jm800318d

• Discovery of 4-Aryl-4H-chromenes as a New Series of Apoptosis Inducers Using a Cell- and Caspase-Based High Throughput Screening Assay. 4. Structure–Activity Relationships of N-Alkyl Substituted Pyrrole Fused at the 7,8-Positions

  Journal of Medicinal Chemistry · 2008 · https://doi.org/10.1021/jm7010657

• Genome-wide Copy-Number-Variation Study Identified a Susceptibility Gene, UGT2B17, for Osteoporosis

  The American Journal of Human Genetics · 2008 · https://doi.org/10.1016/j.ajhg.2008.10.006

• SUMO-2/3 Modification and Binding Regulate the Association of CENP-E with Kinetochores and Progression through Mitosis

  Molecular Cell · 2008 · https://doi.org/10.1016/j.molcel.2008.01.013

• Inhibition of the CXCR4/CXCL12 chemokine pathway reduces the development of murine pulmonary metastases

  Clinical & Experimental Metastasis · 2007 · https://doi.org/10.1007/s10585-007-9133-3

• Design of Biocompatible Chitosan Microgels for Targeted pH-Mediated Intracellular Release of Cancer Therapeutics

  Biomacromolecules · 2006 · https://doi.org/10.1021/bm050912z

• Visceral adipose tissue-derived serine protease inhibitor: A unique insulin-sensitizing adipocytokine in obesity

  Proceedings of the National Academy of Sciences · 2005 · https://doi.org/10.1073/pnas.0504703102

• Monodisperse Chitosan Nanoparticles for Mucosal Drug Delivery

  Biomacromolecules · 2004 · https://doi.org/10.1021/bm0496211

• Expression and functional characterization of ABCG2 in brain endothelial cells and vessels

  The FASEB Journal · 2003 · https://doi.org/10.1096/fj.02-1131fje

• Enzymes of the SUMO Modification Pathway Localize to Filaments of the Nuclear Pore Complex

  Molecular and Cellular Biology · 2002 · https://doi.org/10.1128/mcb.22.18.6498-6508.2002

• Carotenoids Affect Proliferation of Human Prostate Cancer Cells

  Journal of Nutrition · 2001 · https://doi.org/10.1093/jn/131.12.3303

• Structure of a cytochrome P450–redox partner electron-transfer complex

  Proceedings of the National Academy of Sciences · 1999 · https://doi.org/10.1073/pnas.96.5.1863

• DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

  Cell · 1995 · https://doi.org/10.1016/0092-8674(95)90482-4

Current projects

No projects listed.