Yifan Wang

Research interests

Publications

• Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy

  Nature Biomedical Engineering · 2023 · https://doi.org/10.1038/s41551-022-00989-w

• Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy

  Cell · 2022 · https://doi.org/10.1016/j.cell.2022.06.018

• Cancer immunotherapy based on image-guided STING activation by nucleotide nanocomplex-decorated ultrasound microbubbles

  Nature Nanotechnology · 2022 · https://doi.org/10.1038/s41565-022-01134-z

• Updated efficacy and safety data from IMbrave150: Atezolizumab plus bevacizumab vs. sorafenib for unresectable hepatocellular carcinoma

  Journal of Hepatology · 2021 · https://doi.org/10.1016/j.jhep.2021.11.030

• Atezolizumab plus Bevacizumab versus Sorafenib in the Chinese Subpopulation with Unresectable Hepatocellular Carcinoma: Phase 3 Randomized, Open-Label IMbrave150 Study

  Liver Cancer · 2021 · https://doi.org/10.1159/000513486

• Considerations for designing preclinical cancer immune nanomedicine studies

  Nature Nanotechnology · 2020 · https://doi.org/10.1038/s41565-020-00817-9

• Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-020-15129-8

• Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-020-17127-2

• Amyloid‐Like Protein Aggregates: A New Class of Bioinspired Materials Merging an Interfacial Anchor with Antifouling

  Advanced Materials · 2020 · https://doi.org/10.1002/adma.202000128

• Trastuzumab emtansine plus atezolizumab versus trastuzumab emtansine plus placebo in previously treated, HER2-positive advanced breast cancer (KATE2): a phase 2, multicentre, randomised, double-blind trial

  The Lancet Oncology · 2020 · https://doi.org/10.1016/s1470-2045(20)30465-4

• Low-Dose Anti-Angiogenic Therapy Sensitizes Breast Cancer to PD-1 Blockade

  Clinical Cancer Research · 2019 · https://doi.org/10.1158/1078-0432.ccr-19-2179

• Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

  Nature Biomedical Engineering · 2019 · https://doi.org/10.1038/s41551-019-0485-1

• Therapeutic Remodeling of the Tumor Microenvironment Enhances Nanoparticle Delivery

  Advanced Science · 2019 · https://doi.org/10.1002/advs.201802070

• Extracellular vesicles containing miR-146a attenuate experimental colitis by targeting TRAF6 and IRAK1

  International Immunopharmacology · 2019 · https://doi.org/10.1016/j.intimp.2018.12.043

• The Reciprocity between Radiotherapy and Cancer Immunotherapy

  Clinical Cancer Research · 2018 · https://doi.org/10.1158/1078-0432.ccr-18-2581

• Combining Immunotherapy and Radiotherapy for Cancer Treatment: Current Challenges and Future Directions

  Frontiers in Pharmacology · 2018 · https://doi.org/10.3389/fphar.2018.00185

• Multivalent bi-specific nanobioconjugate engager for targeted cancer immunotherapy

  Nature Nanotechnology · 2017 · https://doi.org/10.1038/nnano.2017.69

• Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation

  Nature Communications · 2017 · https://doi.org/10.1038/ncomms14228

• Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer

  Cancer Cell · 2014 · https://doi.org/10.1016/j.ccr.2014.01.028

• The Role of Snail in EMT and Tumorigenesis

  Current Cancer Drug Targets · 2013 · https://doi.org/10.2174/15680096113136660102

• Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance

  Proceedings of the National Academy of Sciences · 2013 · https://doi.org/10.1073/pnas.1305170110

• Epithelial-Mesenchymal Transition—A Hallmark of Breast Cancer Metastasis

  Cancer Hallmarks · 2013 · https://doi.org/10.1166/ch.2013.1004

• G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer

  Journal of Clinical Investigation · 2012 · https://doi.org/10.1172/jci57349

• UCP1 deficiency increases susceptibility to diet‐induced obesity with age

  Aging Cell · 2005 · https://doi.org/10.1111/j.1474-9726.2005.00157.x

Current projects

No projects listed.