Helen Chen

Research interests

Publications

• Transcutaneous auricular vagus nerve stimulation (taVNS) for migraine: an fMRI study

  Regional Anesthesia & Pain Medicine · 2020 · https://doi.org/10.1136/rapm-2020-102088

• A new concordant partial AUC and partial c statistic for imbalanced data in the evaluation of machine learning algorithms

  BMC Medical Informatics and Decision Making · 2020 · https://doi.org/10.1186/s12911-019-1014-6

• Perinatal maternal depressive symptoms alter amygdala functional connectivity in girls

  Human Brain Mapping · 2017 · https://doi.org/10.1002/hbm.23873

• Phase III Prospective Randomized Comparison Trial of Depot Octreotide Plus Interferon Alfa-2b Versus Depot Octreotide Plus Bevacizumab in Patients With Advanced Carcinoid Tumors: SWOG S0518

  Journal of Clinical Oncology · 2017 · https://doi.org/10.1200/jco.2016.70.4072

• Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production

  Cell Metabolism · 2016 · https://doi.org/10.1016/j.cmet.2016.04.022

• Designing a broad-spectrum integrative approach for cancer prevention and treatment

  Seminars in Cancer Biology · 2015 · https://doi.org/10.1016/j.semcancer.2015.09.007

• Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

  Seminars in Cancer Biology · 2015 · https://doi.org/10.1016/j.semcancer.2015.03.005

• Antenatal Maternal Anxiety Predicts Variations in Neural Structures Implicated in Anxiety Disorders in Newborns

  Journal of the American Academy of Child & Adolescent Psychiatry · 2015 · https://doi.org/10.1016/j.jaac.2015.01.013

• Discovery of MK-7655, a β-lactamase inhibitor for combination with Primaxin®

  Bioorganic & Medicinal Chemistry Letters · 2014 · https://doi.org/10.1016/j.bmcl.2013.12.101

• Prenatal Maternal Depression Associates with Microstructure of Right Amygdala in Neonates at Birth

  Biological Psychiatry · 2013 · https://doi.org/10.1016/j.biopsych.2013.06.019

• Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer

  PLoS Biology · 2011 · https://doi.org/10.1371/journal.pbio.1001199

• Phase II Trial Evaluating the Clinical and Biologic Effects of Bevacizumab in Unresectable Hepatocellular Carcinoma

  Journal of Clinical Oncology · 2008 · https://doi.org/10.1200/jco.2007.15.9947

• VEGF as a Marker for Outcome Among Advanced Breast Cancer Patients Receiving anti-VEGF Therapy with Bevacizumab and Vinorelbine Chemotherapy

  Clinical Cancer Research · 2008 · https://doi.org/10.1158/1078-0432.ccr-08-0593

• Phase II Clinical Trial of Bevacizumab and Low-Dose Metronomic Oral Cyclophosphamide in Recurrent Ovarian Cancer: A Trial of the California, Chicago, and Princess Margaret Hospital Phase II Consortia

  Journal of Clinical Oncology · 2007 · https://doi.org/10.1200/jco.2007.12.1939

• Trastuzumab, Paclitaxel, Carboplatin, and Gemcitabine in Advanced Human Epidermal Growth Factor Receptor-2/ neu –Positive Urothelial Carcinoma: Results of a Multicenter Phase II National Cancer Institute Trial

  Journal of Clinical Oncology · 2007 · https://doi.org/10.1200/jco.2006.08.0994

• Advancing translational research with the Semantic Web

  BMC Bioinformatics · 2007 · https://doi.org/10.1186/1471-2105-8-s3-s2

• Antiangiogenic and Antitumor Effects of Bevacizumab in Patients With Inflammatory and Locally Advanced Breast Cancer

  Journal of Clinical Oncology · 2006 · https://doi.org/10.1200/jco.2005.03.4645

• Phase II Study of Doxorubicin and Bevacizumab for Patients With Metastatic Soft-Tissue Sarcomas

  Journal of Clinical Oncology · 2005 · https://doi.org/10.1200/jco.2005.16.139

• Targeting Vascular Endothelial Growth Factor for Relapsed and Refractory Adult Acute Myelogenous Leukemias

  Clinical Cancer Research · 2004 · https://doi.org/10.1158/1078-0432.ccr-03-0627

• A repressor sequence in the juxtamembrane domain of Flt‐1 (VEGFR‐1) constitutively inhibits vascular endothelial growth factor‐dependent phosphatidylinositol 3′‐kinase activation and endothelial cell migration

  The EMBO Journal · 2000 · https://doi.org/10.1093/emboj/19.15.4064

• Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

  Nature · 1996 · https://doi.org/10.1038/380439a0

• Identification of Vascular Endothelial Growth Factor Determinants for Binding KDR and FLT-1 Receptors

  Journal of Biological Chemistry · 1996 · https://doi.org/10.1074/jbc.271.10.5638

• The Carboxyl-terminal Domain(111–165) of Vascular Endothelial Growth Factor Is Critical for Its Mitogenic Potency

  Journal of Biological Chemistry · 1996 · https://doi.org/10.1074/jbc.271.13.7788

Current projects

No projects listed.