Santosh Kesari

Research interests

Publications

• Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma

  JAMA Oncology · 2022 · https://doi.org/10.1001/jamaoncol.2022.5370

• A Review of Persistent Post-COVID Syndrome (PPCS)

  Clinical Reviews in Allergy & Immunology · 2021 · https://doi.org/10.1007/s12016-021-08848-3

• ANG1005, a Brain-Penetrating Peptide–Drug Conjugate, Shows Activity in Patients with Breast Cancer with Leptomeningeal Carcinomatosis and Recurrent Brain Metastases

  Clinical Cancer Research · 2020 · https://doi.org/10.1158/1078-0432.ccr-19-3258

• Lipid–polymer hybrid nanoparticles as a next-generation drug delivery platform: state of the art, emerging technologies, and perspectives

  International Journal of Nanomedicine · 2019 · https://doi.org/10.2147/ijn.s198353

• A Randomized Double-Blind Placebo-Controlled Phase II Trial of Dendritic Cell Vaccine ICT-107 in Newly Diagnosed Patients with Glioblastoma

  Clinical Cancer Research · 2019 · https://doi.org/10.1158/1078-0432.ccr-19-0261

• Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

  Journal of Translational Medicine · 2018 · https://doi.org/10.1186/s12967-018-1611-7

• First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma

  Journal of Translational Medicine · 2018 · 10.1186/s12967-018-1507-6

• Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial

  The Lancet Oncology · 2017 · https://doi.org/10.1016/s1470-2045(17)30517-x

• Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours

  Nature Reviews Neurology · 2016 · https://doi.org/10.1038/nrneurol.2016.185

• A Phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma

  Neuro-Oncology · 2016 · https://doi.org/10.1093/neuonc/now009

• Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma

  JAMA · 2015 · https://doi.org/10.1001/jama.2015.16669

• Diffusion-Weighted Imaging in Cancer: Physical Foundations and Applications of Restriction Spectrum Imaging

  Cancer Research · 2014 · https://doi.org/10.1158/0008-5472.can-13-3534

• miR-21 in the Extracellular Vesicles (EVs) of Cerebrospinal Fluid (CSF): A Platform for Glioblastoma Biomarker Development

  PLoS ONE · 2013 · https://doi.org/10.1371/journal.pone.0078115

• Phase I Pharmacologic and Pharmacodynamic Study of the Gamma Secretase (Notch) Inhibitor MK-0752 in Adult Patients With Advanced Solid Tumors

  Journal of Clinical Oncology · 2012 · https://doi.org/10.1200/jco.2011.39.1540

• Autoantigen discovery with a synthetic human peptidome

  Nature Biotechnology · 2011 · https://doi.org/10.1038/nbt.1856

• Transdifferentiation of glioblastoma cells into vascular endothelial cells

  Proceedings of the National Academy of Sciences · 2011 · https://doi.org/10.1073/pnas.1016030108

• Corticosteroids in brain cancer patients: benefits and pitfalls

  Expert Review of Clinical Pharmacology · 2011 · https://doi.org/10.1586/ecp.11.1

• Human Glioma Growth Is Controlled by MicroRNA-10b

  Cancer Research · 2011 · https://doi.org/10.1158/0008-5472.can-10-3568

• Single-Agent Bortezomib in Previously Untreated Multiple Myeloma: Efficacy, Characterization of Peripheral Neuropathy, and Molecular Correlations With Response and Neuropathy

  Journal of Clinical Oncology · 2009 · https://doi.org/10.1200/jco.2008.18.3087

• Human Glioblastoma–Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors

  Cancer Research · 2009 · https://doi.org/10.1158/0008-5472.can-08-3886

• MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

  Molecular and Cellular Biology · 2008 · https://doi.org/10.1128/mcb.00479-08

• Malignant Gliomas in Adults

  New England Journal of Medicine · 2008 · https://doi.org/10.1056/nejmra0708126

• Bevacizumab for recurrent malignant gliomas

  Neurology · 2008 · https://doi.org/10.1212/01.wnl.0000304121.57857.38

• Olig2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma

  Neuron · 2007 · https://doi.org/10.1016/j.neuron.2007.01.009

• Response and Resistance in a Non–Small-Cell Lung Cancer Patient With an Epidermal Growth Factor Receptor Mutation and Leptomeningeal Metastases Treated With High-Dose Gefitinib

  Journal of Clinical Oncology · 2006 · https://doi.org/10.1200/jco.2006.06.6126

Current projects

No projects listed.