Otávio Henrique Thiemann

Research interests

Publications

• The therapeutic strategies against Naegleria fowleri

  Experimental Parasitology · 2018 · 10.1016/j.exppara.2018.02.010

• The unique tRNASec and its role in selenocysteine biosynthesis

  Amino Acids · 2018 · 10.1007/s00726-018-2595-6

• Chromatin Proteomics Reveals Variable Histone Modifications during the Life Cycle of Trypanosoma cruzi

  Journal of Proteome Research · 2016 · 10.1021/acs.jproteome.6b00208

• In vivo and in vitro auranofin activity against Trypanosoma cruzi: Possible new uses for an old drug

  Experimental Parasitology · 2015 · 10.1016/j.exppara.2015.05.012

• Role of Δ1-Pyrroline-5-Carboxylate Dehydrogenase Supports Mitochondrial Metabolism and Host-Cell Invasion of Trypanosoma cruzi

  Journal of Biological Chemistry · 2015 · 10.1074/jbc.m114.574525

• Leishmaniasis and Chagas Disease Chemotherapy: a Critical Review

  Journal of the Brazilian Chemical Society · 2014 · 10.5935/0103-5053.20140229

• Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites

  Bioorganic & Medicinal Chemistry · 2009 · 10.1016/j.bmc.2009.01.068

• Quimioterapia da doença de Chagas: estado da arte e perspectivas no desenvolvimento de novos fármacos

  Química Nova · 2009 · 10.1590/s0100-40422009000900038

• A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felina

  Química Nova · 2008 · 10.1590/s0100-40422008000500030

• Biological activities from extracts of endophytic fungi isolated fromViguiera arenariaandTithonia diversifolia

  FEMS Immunology & Medical Microbiology · 2008 · 10.1111/j.1574-695x.2007.00354.x

• Isolamento e atividades biológicas de produtos naturais das esponjas monanchora arbuscula, aplysina sp. petromica ciocalyptoides e topsentia ophiraphidites, da ascídia didemnum ligulum e do octocoral carijoa riisei

  Química Nova · 2007 · 10.1590/s0100-40422007000500027

• Antibiotic, cytotoxic and enzyme inhibitory activity of crude extracts from Brazilian marine invertebrates

  Revista Brasileira de Farmacognosia · 2007 · 10.1590/s0102-695x2007000300002

• Sulfated Meroterpenoids from the Brazilian Sponge Callyspongia sp. Are Inhibitors of the Antileishmaniasis Target Adenosine Phosphoribosyl Transferase

  The Journal of Organic Chemistry · 2006 · 10.1021/jo060295k

• Identification of Leishmania selenoproteins and SECIS element

  Molecular and Biochemical Parasitology · 2006 · 10.1016/j.molbiopara.2006.05.002

• The crystal structure of glucose‐6‐phosphate isomerase from Leishmania mexicana reveals novel active site features

  European Journal of Biochemistry · 2004 · 10.1111/j.1432-1033.2004.04205.x

• Challenges and Rewards of Research in Marine Natural Products Chemistry in Brazil

  Journal of Natural Products · 2004 · 10.1021/np0304316

• Aurapten, a coumarin with growth inhibition against Leishmania major promastigotes

  Brazilian Journal of Medical and Biological Research · 2004 · 10.1590/s0100-879x2004001200010

• Evaluation of Monocot and Eudicot Divergence Using the Sugarcane Transcriptome

  PLANT PHYSIOLOGY · 2004 · 10.1104/pp.103.033878

• Kinetic characterization, structure modelling studies and crystallization of Trypanosoma brucei enolase

  European Journal of Biochemistry · 2003 · 10.1046/j.1432-1033.2003.03692.x

• Crystal structure of human phosphoglucose isomerase and analysis of the initial catalytic steps

  Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 2003 · 10.1016/s1570-9639(02)00464-8

• A sugarcane cystatin: recombinant expression, purification, and antifungal activity

  Biochemical and Biophysical Research Communications · 2002 · 10.1016/s0006-291x(02)02046-6

• Evolution of RNA editing in trypanosome mitochondria

  Proceedings of the National Academy of Sciences · 2000 · 10.1073/pnas.97.13.6986

• Sense from nonsense: RNA editing in mitochondria of kinetoplastid protozoa and slime molds

  Cell · 1995 · 10.1016/0092-8674(95)90003-9

• Disruption of RNA editing in Leishmania tarentolae by the loss of minicircle‐encoded guide RNA genes.

  The EMBO Journal · 1994 · 10.1002/j.1460-2075.1994.tb06907.x

• Detection of Trypanosoma cruzi in blood specimens of chronic chagasic patients by polymerase chain reaction amplification of kinetoplast minicircle DNA: comparison with serology and xenodiagnosis

  Journal of Clinical Microbiology · 1993 · 10.1128/jcm.31.9.2421-2426.1993

Current projects

No projects listed.