José E. Tanus‐Santos

Research interests

Publications

• Endothelial nitric oxide synthase: From biochemistry and gene structure to clinical implications of NOS3 polymorphisms

  Gene · 2015 · 10.1016/j.gene.2015.09.061

• Hemolysis during cardiac surgery is associated with increased intravascular nitric oxide consumption and perioperative kidney and intestinal tissue damage

  Frontiers in Physiology · 2014 · 10.3389/fphys.2014.00340

• Sodium nitrite downregulates vascular NADPH oxidase and exerts antihypertensive effects in hypertension

  Free Radical Biology and Medicine · 2011 · 10.1016/j.freeradbiomed.2011.04.005

• Gingival crevicular fluid levels of MMP‐8, MMP‐9, TIMP‐2, and MPO decrease after periodontal therapy

  Journal Of Clinical Periodontology · 2009 · 10.1111/j.1600-051x.2009.01512.x

• Imbalance between matrix metalloproteinases and tissue inhibitor of metalloproteinases in hypertensive vascular remodeling

  Matrix Biology · 2009 · 10.1016/j.matbio.2009.11.005

• Circulating Interleukin‐6 and High‐Sensitivity C‐Reactive Protein Decrease After Periodontal Therapy in Otherwise Healthy Subjects

  Journal of Periodontology · 2009 · 10.1902/jop.2009.080561

• Antioxidant treatment reduces matrix metalloproteinase-2-induced vascular changes in renovascular hypertension

  Free Radical Biology and Medicine · 2009 · 10.1016/j.freeradbiomed.2009.02.011

• Comparative assessment of matrix metalloproteinase (MMP)-2 and MMP-9, and their inhibitors, tissue inhibitors of metalloproteinase (TIMP)-1 and TIMP-2 in preeclampsia and gestational hypertension

  Clinical Biochemistry · 2008 · 10.1016/j.clinbiochem.2008.04.015

• Nitric Oxide Formation Is Inversely Related to Serum Levels of Antiangiogenic Factors Soluble Fms-Like Tyrosine Kinase-1 and Soluble Endogline in Preeclampsia

  Hypertension · 2008 · 10.1161/hypertensionaha.108.115006

• Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats

  Atherosclerosis · 2007 · 10.1016/j.atherosclerosis.2007.10.011

• Modulation of nitric oxide formation by endothelial nitric oxide synthase gene haplotypes

  Free Radical Biology and Medicine · 2007 · 10.1016/j.freeradbiomed.2007.06.012

• Rapid separation of serum does not avoid artificially higher matrix metalloproteinase (MMP)-9 levels in serum versus plasma

  Clinical Biochemistry · 2006 · 10.1016/j.clinbiochem.2006.10.007

• A critical review of biomarkers used for monitoring human exposure to lead: advantages, limitations and future needs

  Ciência & Saúde Coletiva · 2006 · 10.1590/s1413-81232006000100032

• Susceptible and protective eNOS haplotypes in hypertensive black and white subjects

  Atherosclerosis · 2005 · 10.1016/j.atherosclerosis.2005.08.003

• A Critical Review of Biomarkers Used for Monitoring Human Exposure to Lead: Advantages, Limitations, and Future Needs

  Environmental Health Perspectives · 2005 · https://doi.org/10.1289/ehp.7917

• Consistent interethnic differences in the distribution of clinically relevant endothelial nitric oxide synthase genetic polymorphisms

  Nitric Oxide · 2005 · 10.1016/j.niox.2005.02.002

• Effect of anticoagulants on the determination of plasma matrix metalloproteinase (MMP)-2 and MMP-9 activities

  Analytical Biochemistry · 2005 · 10.1016/j.ab.2005.04.038

• Methodological issues affecting the determination of plasma matrix metalloproteinase (MMP)-2 and MMP-9 activities

  Clinical Biochemistry · 2005 · 10.1016/j.clinbiochem.2005.02.010

• Endothelial nitric oxide synthase gene haplotypes associated with circulating concentrations of nitric oxide products in healthy men

  Pharmacogenetics and Genomics · 2005 · 10.1097/01.fpc.0000167328.85163.44

• Biological activity of nitric oxide in the plasmatic compartment

  Proceedings of the National Academy of Sciences · 2004 · 10.1073/pnas.0402201101

• Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease

  Nature Medicine · 2002 · https://doi.org/10.1038/nm1202-799

• Effects of endothelial nitric oxide synthase gene polymorphisms on platelet function, nitric oxide release, and interactions with estradiol

  Pharmacogenetics · 2002 · 10.1097/00008571-200207000-00008

• Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease

  Nature Medicine · 2002 · https://doi.org/10.1038/nm799

• Implications of Cytochrome P450 Interactions When Prescribing Medication for Hypertension

  Archives of Internal Medicine · 2002 · 10.1001/archinte.162.4.405

• Effects of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants

  Pharmacogenetics · 2001 · https://doi.org/10.1097/00008571-200111000-00011

Current projects

No projects listed.