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Shinya Kimura

Researcher Next ID · RN-038171

Researcher · Medicine

Saga University

Saga, Norway

Accepting doctoral researchersFunding unknown
Works count
781
Citation count
10,545
H-index
53
i10-index
233

Research interests

Medicine
Chronic Myeloid Leukemia Treatments
Chronic Lymphocytic Leukemia Research
Acute Myeloid Leukemia Research
Eosinophilic Disorders and Syndromes
Lymphoma Diagnosis and Treatment

Publications

  • Prognostic impact of CEBPA bZIP domain mutation in acute myeloid leukemia

    Blood Advances · 2021 · 10.1182/bloodadvances.2021004292

  • Treatment-free remission after first-line dasatinib discontinuation in patients with chronic myeloid leukaemia (first-line DADI trial): a single-arm, multicentre, phase 2 trial

    The Lancet Haematology · 2020 · 10.1016/s2352-3026(19)30235-2

  • Prognostic impact of low allelic ratio FLT3-ITD and NPM1 mutation in acute myeloid leukemia

    Blood Advances · 2018 · 10.1182/bloodadvances.2018020305

  • Final 3-year Results of the Dasatinib Discontinuation Trial in Patients With Chronic Myeloid Leukemia Who Received Dasatinib as a Second-line Treatment

    Clinical Lymphoma Myeloma & Leukemia · 2018 · 10.1016/j.clml.2018.03.004

  • Saturated Fatty Acid Increases Lung Macrophages and Augments House Dust Mite-Induced Airway Inflammation in Mice Fed with High-Fat Diet

    Inflammation · 2017 · 10.1007/s10753-017-0550-4

  • The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells

    Blood Cancer Journal · 2017 · 10.1038/bcj.2017.8

  • 2-Hydroxypropyl-β-Cyclodextrin Acts as a Novel Anticancer Agent

    PLoS ONE · 2015 · 10.1371/journal.pone.0141946

  • Discontinuation of dasatinib in patients with chronic myeloid leukaemia who have maintained deep molecular response for longer than 1 year (DADI trial): a multicentre phase 2 trial

    The Lancet Haematology · 2015 · https://doi.org/10.1016/s2352-3026(15)00196-9

  • Induction of p53‐mediated transcription and apoptosis by exportin‐1 ( XPO 1) inhibition in mantle cell lymphoma

    Cancer Science · 2014 · 10.1111/cas.12430

  • CXCR4 up-regulation by imatinib induces chronic myelogenous leukemia (CML) cell migration to bone marrow stroma and promotes survival of quiescent CML cells

    Molecular Cancer Therapeutics · 2008 · 10.1158/1535-7163.mct-07-0042

  • Comparison of imatinib, dasatinib, nilotinib and INNO-406 in imatinib-resistant cell lines

    Leukemia Research · 2008 · 10.1016/j.leukres.2007.11.008

  • ABT‐737 is a useful component of combinatory chemotherapies for chronic myeloid leukaemias with diverse drug‐resistance mechanisms

    British Journal of Haematology · 2007 · 10.1111/j.1365-2141.2007.06899.x

  • Zoledronic Acid -a Multiplicity of Anti-Cancer Action

    Current Medicinal Chemistry · 2007 · 10.2174/092986707781389600

  • Bim and Bad mediate imatinib-induced killing of Bcr/Abl + leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic

    Proceedings of the National Academy of Sciences · 2006 · 10.1073/pnas.0606176103

  • Comparison of Human Herpes Virus 8 Related Primary Effusion Lymphoma with Human Herpes Virus 8 Unrelated Primary Effusion Lymphoma-Like Lymphoma on the Basis of HIV: Report of 2 Cases and Review of 212 Cases in the Literature

    Acta Haematologica · 2006 · 10.1159/000097460

  • INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity

    Blood · 2006 · 10.1182/blood-2006-03-013250

  • Cytotoxic effects of γδ T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy

    International Journal of Cancer · 2005 · 10.1002/ijc.20987

  • Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer

    Journal of Clinical Investigation · 2005 · 10.1172/jci23043

  • NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia

    Blood · 2005 · 10.1182/blood-2005-06-2209

  • Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models

    Cancer Letters · 2004 · 10.1016/j.canlet.2004.07.010

  • Efficacy of the third-generation bisphosphonate, zoledronic acid alone and combined with anti-cancer agents against small cell lung cancer cell lines

    Lung Cancer · 2004 · 10.1016/j.lungcan.2004.06.003

  • Cyclin G1 associates with MDM2 and regulates accumulation and degradation of p53 protein

    Genes to Cells · 2002 · 10.1046/j.1365-2443.2002.00564.x

  • Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery

    Oncogene · 2001 · 10.1038/sj.onc.1204270

  • Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin

    Proceedings of the National Academy of Sciences · 1998 · 10.1073/pnas.95.3.1195

  • GAK: a cyclin G associated kinase contains a tensin/auxilin‐like domain1

    FEBS Letters · 1997 · 10.1016/s0014-5793(96)01484-6

Current projects

    No projects listed.