Kjetil Taskén

Research interests

Publications

• FOXK1 and FOXK2 regulate aerobic glycolysis

  Nature · 2019 · https://doi.org/10.1038/s41586-019-0900-5

• Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects

  Journal of Allergy and Clinical Immunology · 2018 · https://doi.org/10.1016/j.jaci.2018.02.055

• Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells – Role of Anchored Protein Kinase A Signaling Units

  Frontiers in Immunology · 2016 · https://doi.org/10.3389/fimmu.2016.00222

• Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans

  Cell Reports · 2016 · https://doi.org/10.1016/j.celrep.2016.04.005

• Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry

  Cancer Immunology Immunotherapy · 2015 · https://doi.org/10.1007/s00262-015-1729-x

• Creating Order from Chaos: Cellular Regulation by Kinase Anchoring

  The Annual Review of Pharmacology and Toxicology · 2012 · https://doi.org/10.1146/annurev-pharmtox-011112-140204

• Specificity and spatial dynamics of protein kinase A signaling organized by A-kinase-anchoring proteins

  Journal of Molecular Endocrinology · 2010 · https://doi.org/10.1677/jme-10-0010

• Cyclic AMP-mediated immune regulation — Overview of mechanisms of action in T cells

  Cellular Signalling · 2010 · https://doi.org/10.1016/j.cellsig.2010.11.018

• PI3K p110δ regulates T-cell cytokine production during primary and secondary immune responses in mice and humans

  Blood · 2010 · https://doi.org/10.1182/blood-2009-07-232330

• AKAP complex regulates Ca2+ re‐uptake into heart sarcoplasmic reticulum

  EMBO Reports · 2007 · https://doi.org/10.1038/sj.embor.7401081

• FOXP3+CD4+CD25+ Adaptive Regulatory T Cells Express Cyclooxygenase-2 and Suppress Effector T Cells by a Prostaglandin E2-Dependent Mechanism

  The Journal of Immunology · 2006 · https://doi.org/10.4049/jimmunol.177.1.246

• Molecular Basis of AKAP Specificity for PKA Regulatory Subunits

  Molecular Cell · 2006 · https://doi.org/10.1016/j.molcel.2006.09.006

• Delineation of Type I Protein Kinase A-selective Signaling Events Using an RI Anchoring Disruptor

  Journal of Biological Chemistry · 2006 · https://doi.org/10.1074/jbc.m603223200

• Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

  Nature Genetics · 2005 · https://doi.org/10.1038/ng1673

• Localized Effects of cAMP Mediated by Distinct Routes of Protein Kinase A

  Physiological Reviews · 2004 · https://doi.org/10.1152/physrev.00021.2003

• Positive and negative regulation of T-cell activation through kinases and phosphatases

  Biochemical Journal · 2003 · https://doi.org/10.1042/bj20021637

• Molecular mechanisms for protein kinase A-mediated modulation of immune function

  Cellular Signalling · 2002 · https://doi.org/10.1016/s0898-6568(01)00214-5

• Activation of the Cooh-Terminal Src Kinase (Csk) by Camp-Dependent Protein Kinase Inhibits Signaling through the T Cell Receptor

  The Journal of Experimental Medicine · 2001 · https://doi.org/10.1084/jem.193.4.497

• FOXC2 Is a Winged Helix Gene that Counteracts Obesity, Hypertriglyceridemia, and Diet-Induced Insulin Resistance

  Cell · 2001 · https://doi.org/10.1016/s0092-8674(01)00474-3

• Release from Tonic Inhibition of T Cell Activation through Transient Displacement of C-terminal Src Kinase (Csk) from Lipid Rafts

  Journal of Biological Chemistry · 2001 · https://doi.org/10.1074/jbc.c100014200

• Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding

  Journal of Molecular Biology · 2000 · https://doi.org/10.1006/jmbi.2000.3662

• Recruitment of Protein Phosphatase 1 to the Nuclear Envelope by a-Kinase Anchoring Protein Akap149 Is a Prerequisite for Nuclear Lamina Assembly

  The Journal of Cell Biology · 2000 · https://doi.org/10.1083/jcb.150.6.1251

• Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase

  Nature Cell Biology · 1999 · https://doi.org/10.1038/13024

• 16 Structure, function, and regulation of human cAMP-dependent protein kinases

  Advances in second messenger and phosphoprotein research · 1997 · https://doi.org/10.1016/s1040-7952(97)80019-5

• Location of cAMP-Dependent Protein Kinase Type I with the TCR-CD3 Complex

  Science · 1994 · https://doi.org/10.1126/science.8272870

Current projects

No projects listed.