Øystein Bruserud

Research interests

Publications

• Mesenchymal Stem Cells Support Survival and Proliferation of Primary Human Acute Myeloid Leukemia Cells through Heterogeneous Molecular Mechanisms

  Frontiers in Immunology · 2017 · 10.3389/fimmu.2017.00106

• Co-transplantation of multipotent mesenchymal stromal cells in allogeneic hematopoietic stem cell transplantation: A systematic review and meta-analysis

  Cytotherapy · 2016 · 10.1016/j.jcyt.2015.11.010

• Expansion of myeloid derived suppressor cells correlates with number of T regulatory cells and disease progression in myelodysplastic syndrome

  OncoImmunology · 2015 · 10.1080/2162402x.2015.1062208

• Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia

  Leukemia · 2014 · 10.1038/leu.2014.89

• Therapeutic Targeting the Cell Division Cycle 25 (CDC25) Phosphatases in Human Acute Myeloid Leukemia — The Possibility to Target Several Kinases through Inhibition of the Various CDC25 Isoforms

  Molecules · 2014 · 10.3390/molecules191118414

• SIRT1 Activation by a c-MYC Oncogenic Network Promotes the Maintenance and Drug Resistance of Human FLT3-ITD Acute Myeloid Leukemia Stem Cells

  Cell stem cell · 2014 · 10.1016/j.stem.2014.08.001

• Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents

  Clinical Epigenetics · 2013 · 10.1186/1868-7083-5-12

• The role of arginine and arginine-metabolizing enzymes during Giardia – host cell interactions in vitro

  BMC Microbiology · 2013 · 10.1186/1471-2180-13-256

• Acute Myeloid Leukemia with the t(8;21) Translocation: Clinical Consequences and Biological Implications

  BioMed Research International · 2011 · 10.1155/2011/104631

• Intensive chemotherapy for acute myeloid leukemia differentially affects circulating TC1, TH1, TH17 and TREG cells

  BMC Immunology · 2010 · 10.1186/1471-2172-11-38

• The Crosstalk Between the Matrix Metalloprotease System and the Chemokine Network in Acute Myeloid Leukemia

  Current Medicinal Chemistry · 2010 · 10.2174/092986710794183033

• The proteasome inhibitors bortezomib and PR‐171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells

  British Journal of Haematology · 2007 · 10.1111/j.1365-2141.2007.06504.x

• Subclassification of patients with acute myelogenous leukemia based on chemokine responsiveness and constitutive chemokine release by their leukemic cells

  Haematologica · 2007 · 10.3324/haematol.10148

• Histone Deacetylase Inhibitors in Cancer Treatment: A Review of the Clinical Toxicity and the Modulation of Gene Expression in Cancer Cells

  Current Pharmaceutical Biotechnology · 2007 · 10.2174/138920107783018417

• In vitro evaluation of metabolic changes and residual platelet responsiveness in photochemical treated and gamma‐irradiated single‐donor platelet concentrates during long‐term storage

  Transfusion · 2007 · 10.1111/j.1537-2995.2007.01167.x

• Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53

  Blood · 2006 · 10.1182/blood-2006-02-004234

• A phase II trial of pegylated interferon α‐2b therapy for polycythemia vera and essential thrombocythemia

  Cancer · 2006 · 10.1002/cncr.21900

• A Distinct p53 Protein Isoform Signature Reflects the Onset of Induction Chemotherapy for Acute Myeloid Leukemia

  Clinical Cancer Research · 2006 · 10.1158/1078-0432.ccr-05-1970

• Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts

  International Journal of Cancer · 2006 · 10.1002/ijc.22180

• Animal models of acute myelogenous leukaemia – development, application and future perspectives

  Leukemia · 2005 · 10.1038/sj.leu.2403670

• Single Cell Profiling of Potentiated Phospho-Protein Networks in Cancer Cells

  Cell · 2004 · https://doi.org/10.1016/j.cell.2004.06.028

• Osteoblasts increase proliferation and release of pro-angiogenic interleukin 8 by native human acute myelogenous leukemia blasts.

  PubMed · 2004

• Flt3-mediated signaling in human acute myelogenous leukemia (AML) blasts: a functional characterization of Flt3-ligand effects in AML cell populations with and without genetic Flt3 abnormalities.

  PubMed · 2003

• Cryopreserving human peripheral blood progenitor cells with 5‐percent rather than 10‐percent DMSO results in less apoptosis and necrosis in CD34+ cells

  Transfusion · 2002 · 10.1046/j.1537-2995.2002.00242.x

• New Strategies in the Treatment of Acute Myelogenous Leukemia (AML): In Vitro Culture of AML Cells—The Present Use in Experimental Studies and the Possible Importance for Future Therapeutic Approaches

  Stem Cells · 2001 · 10.1634/stemcells.19-1-1

Current projects

No projects listed.