Justin D. Lathia

Research interests

Publications

• Immunotherapy for glioblastoma: current state, challenges, and future perspectives

  Cellular and Molecular Immunology · 2024 · 10.1038/s41423-024-01226-x

• Cancer stem cell–immune cell crosstalk in tumour progression

  Nature reviews. Cancer · 2021 · 10.1038/s41568-021-00366-w

• Myeloid-Derived Suppressor Cell Subsets Drive Glioblastoma Growth in a Sex-Specific Manner

  Cancer Discovery · 2020 · https://doi.org/10.1158/2159-8290.cd-19-1355

• Sex differences in GBM revealed by analysis of patient imaging, transcriptome, and survival data

  Science Translational Medicine · 2019 · https://doi.org/10.1126/scitranslmed.aao5253

• Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models

  Cancer Discovery · 2018 · 10.1158/2159-8290.cd-18-0065

• Targeting Cancer Stemness in the Clinic: From Hype to Hope

  Cell stem cell · 2018 · 10.1016/j.stem.2018.11.017

• An anatomic transcriptional atlas of human glioblastoma

  Science · 2018 · https://doi.org/10.1126/science.aaf2666

• Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion

  Stem Cells · 2016 · https://doi.org/10.1002/stem.2393

• Cancer stem cells in glioblastoma

  Genes & Development · 2015 · https://doi.org/10.1101/gad.261982.115

• Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells

  Cancer Cell · 2015 · https://doi.org/10.1016/j.ccell.2015.09.002

• High-speed coherent Raman fingerprint imaging of biological tissues

  Nature Photonics · 2014 · 10.1038/nphoton.2014.145

• Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake

  Nature Neuroscience · 2013 · 10.1038/nn.3510

• Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth

  Cell · 2013 · https://doi.org/10.1016/j.cell.2013.02.021

• Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A

  The Journal of Experimental Medicine · 2013 · 10.1084/jem.20131195

• Autocrine VEGF–VEGFR2–Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

  The Journal of Experimental Medicine · 2012 · 10.1084/jem.20111424

• Deadly Teamwork: Neural Cancer Stem Cells and the Tumor Microenvironment

  Cell stem cell · 2011 · 10.1016/j.stem.2011.04.013

• Glioma Stem Cell Proliferation and Tumor Growth Are Promoted by Nitric Oxide Synthase-2

  Cell · 2011 · 10.1016/j.cell.2011.06.006

• Integrin Alpha 6 Regulates Glioblastoma Stem Cells

  Cell stem cell · 2010 · 10.1016/j.stem.2010.02.018

• Hypoxia inducible factors in cancer stem cells

  British Journal of Cancer · 2010 · 10.1038/sj.bjc.6605551

• Acidic stress promotes a glioma stem cell phenotype

  Cell Death and Differentiation · 2010 · 10.1038/cdd.2010.150

• Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth

  Stem Cells · 2009 · 10.1002/stem.188

• Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

  Cancer Cell · 2009 · https://doi.org/10.1016/j.ccr.2009.03.018

• Notch Promotes Radioresistance of Glioma Stem Cells

  Stem Cells · 2009 · 10.1002/stem.261

• c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells

  PLoS ONE · 2008 · 10.1371/journal.pone.0003769

• Acute Kidney Injury Leads to Inflammation and Functional Changes in the Brain

  Journal of the American Society of Nephrology · 2008 · 10.1681/asn.2007080901

• Toll-like receptors in neurodegeneration

  Brain Research Reviews · 2008 · 10.1016/j.brainresrev.2008.09.001

• Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

  Proceedings of the National Academy of Sciences · 2007 · https://doi.org/10.1073/pnas.0702553104

Current projects

No projects listed.