Per Guldberg

Research interests

Publications

• TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy

  Blood · 2017 · https://doi.org/10.1182/blood-2017-04-779736

• Quantitative comparison of DNA methylation assays for biomarker development and clinical applications

  Nature Biotechnology · 2016 · 10.1038/nbt.3605

• Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the V600EBRAF oncogene

  Oncotarget · 2013 · 10.18632/oncotarget.965

• The genome and epigenome of malignant melanoma

  Apmis · 2007 · 10.1111/j.1600-0463.2007.apm_855.xml.x

• Tumorigenic Heterogeneity in Cancer Stem Cells Evolved from Long-term Cultures of Telomerase-Immortalized Human Mesenchymal Stem Cells

  Cancer Research · 2005 · 10.1158/0008-5472.can-04-2218

• Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early‐stage patients

  European Journal Of Haematology · 2005 · 10.1111/j.1600-0609.2005.00559.x

• DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

  Nature · 2005 · https://doi.org/10.1038/nature03482

• Adult human mesenchymal stem cell as a target for neoplastic transformation

  Oncogene · 2004 · https://doi.org/10.1038/sj.onc.1207651

• DNA methylation analysis techniques

  Biogerontology · 2003 · 10.1023/a:1025103319328

• Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2′-deoxycytidine (decitabine) treatment

  Blood · 2002 · https://doi.org/10.1182/blood.v100.8.2957

• In-Tube DNA Methylation Profiling by Fluorescence Melting Curve Analysis

  Clinical Chemistry · 2001 · 10.1093/clinchem/47.7.1183

• A European Multicenter Study of Phenylalanine Hydroxylase Deficiency: Classification of 105 Mutations and a General System for Genotype-Based Prediction of Metabolic Phenotype

  The American Journal of Human Genetics · 1998 · https://doi.org/10.1086/301920

• Somatic Fas Mutations in Non-Hodgkin’s Lymphoma: Association With Extranodal Disease and Autoimmunity

  Blood · 1998 · 10.1182/blood.v92.9.3018

• Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma.

  PubMed · 1997

• Spontaneous human squamous cell carcinomas are killed by a human cytotoxic T lymphocyte clone recognizing a wild-type p53-derived peptide

  Proceedings of the National Academy of Sciences · 1996 · 10.1073/pnas.93.25.14704

• The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis.

  PubMed · 1996

• Molecular Analysis of Phenylketonuria in Denmark: 99% of the Mutations Detected by Denaturing Gradient Gel Electrophoresis

  Genomics · 1993 · 10.1006/geno.1993.1295

• Assignment of an autosomal sex reversa– locus (SRA1) and campomelic dysplasia (CMPD1) to 17q24.3–q25.1

  Nature Genetics · 1993 · 10.1038/ng0693-170

Current projects

No projects listed.