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Erik B. Pedersen

Researcher Next ID · RN-038606

Researcher · Biochemistry, Genetics and Molecular Biology

University of Southern Denmark

Odense, Denmark

Accepting doctoral researchersFunding unknown
Works count
718
Citation count
7,850
H-index
43
i10-index
210

Research interests

Biochemistry, Genetics and Molecular Biology
Chemistry
Medicine
Synthesis and Characterization of Heterocyclic Compounds
DNA and Nucleic Acid Chemistry
HIV/AIDS drug development and treatment
Synthesis and Reactions of Organic Compounds
Carbohydrate Chemistry and Synthesis

Publications

  • The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription

    Nucleic Acids Research · 2017 · 10.1093/nar/gkx1142

  • GC-elements controlling HRAS transcription form i-motif structures unfolded by heterogeneous ribonucleoprotein particle A1

    Scientific Reports · 2015 · 10.1038/srep18097

  • MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice

    Nucleic Acids Research · 2013 · 10.1093/nar/gkt127

  • G4-DNA Formation in the HRAS Promoter and Rational Design of Decoy Oligonucleotides for Cancer Therapy

    PLoS ONE · 2011 · 10.1371/journal.pone.0024421

  • Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids

    Nucleic Acids Research · 2010 · 10.1093/nar/gkq1133

  • Identification of a New G-Quadruplex Motif in the KRAS Promoter and Design of Pyrene-Modified G4-Decoys with Antiproliferative Activity in Pancreatic Cancer Cells

    Journal of Medicinal Chemistry · 2008 · 10.1021/jm800874t

  • Stabilization of Parallel Triplexes by Twisted Intercalating Nucleic Acids (TINAs) Incorporating 1,2,3‐Triazole Units and Prepared by Microwave‐Accelerated Click Chemistry

    Chemistry - A European Journal · 2007 · 10.1002/chem.200700053

  • Stable and Selective Formation of Hoogsteen-Type Triplexes and Duplexes Using Twisted Intercalating Nucleic Acids (TINA) Prepared via Postsynthetic Sonogashira Solid-Phase Coupling Reactions

    Journal of the American Chemical Society · 2005 · 10.1021/ja053645d

  • Synthesis of Novel N-1 (Allyloxymethyl) Analogues of 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine) with Improved Activity Against HIV-1 and Its Mutants

    Journal of Medicinal Chemistry · 2002 · 10.1021/jm020949r

  • The Flourishing Syntheses of Non-Nucleoside Reverse Transcriptase Inhibitors

    Synthesis · 2000 · 10.1055/s-2000-6357

  • Non-Nucleoside Reverse Transcriptase Inhibitors: The NNRTI Boom

    Antiviral chemistry & chemotherapy · 1999 · 10.1177/095632029901000601

  • Synthesis of Triazenopyrazole Derivativesas Potential Inhibitors of HIV-1

    Monatshefte für Chemie - Chemical Monthly · 1999 · 10.1007/pl00010295

  • Synthesis and Anti-HIV-1 Activity of Novel 2,3-Dihydro-7H-thiazolo[3,2-a]pyrimidin-7-ones

    Journal of Medicinal Chemistry · 1998 · 10.1021/jm970443m

  • S-Glucosylated hydantoins as new antiviral agents

    Journal of Medicinal Chemistry · 1994 · 10.1021/jm00027a009

  • ESR characterization of trans-diacidatotetrakis(pyridine)vanadium and -manganese trans-VII(py)4X2 and trans-MnII(py)4X2 (X = NCS, Cl, Br, I; py = pyridine)

    Inorganic Chemistry · 1993 · 10.1021/ic00059a031

  • Binuclear bis(.mu.-oxo)dimanganese(III,IV) and -(IV,IV) complexes with N,N'-bis(2-pyridylmethyl)-1,2-ethanediamine

    Inorganic Chemistry · 1990 · 10.1021/ic00328a034

  • Recent basic research in hydrodesulfurization catalysis

    Industrial & Engineering Chemistry Fundamentals · 1986 · 10.1021/i100021a004

  • Preparation and Structure of Al3Ti.

    Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 1986 · 10.3891/acta.chem.scand.40a-0157

  • A Novel Correlation between Magnetism and Structural Parameters in Superexchange Coupled Chromium(III) Dimers.

    Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 1983 · 10.3891/acta.chem.scand.37a-0161

  • Magnetic and electrochemical properties of transition metal complexes with multiple metal-to-metal bonds. II. Tetrabutyratodiruthenium(n+) with n = 0 and 1

    Inorganic Chemistry · 1975 · 10.1021/ic50144a035

  • Electron spin resonance spectra of tetragonal chromium(III) complexes. I. trans-[Cr(NH3)4XY]n+ and trans-Cr(py)4XY]n+ in frozen solutions and powders. Correlation between zero-field splittings and ligand field parameters via complete d-electron calculations

    Inorganic Chemistry · 1974 · 10.1021/ic50137a013

  • Magnetic Properties and Molecular Structure of the mu-Oxo-bis{pentaamminechromium(III)} Ion.

    Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 1972 · 10.3891/acta.chem.scand.26-0333

  • Preparation of Chromium(III) Complexes with Two Fluorine Atoms and Four Nitrogen Atoms as Ligators. trans-Difluorotetrakis(pyridine)chromium(III) Salts as Initial Materials.

    Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 1970 · 10.3891/acta.chem.scand.24-0247

Current projects

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