Krister Wennerberg

Research interests

Publications

• Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia

  Cancer Discovery · 2021 · https://doi.org/10.1158/2159-8290.cd-21-0410

• Immunogenomic Landscape of Hematological Malignancies

  Cancer Cell · 2020 · https://doi.org/10.1016/j.ccell.2020.06.002

• Prediction of drug combination effects with a minimal set of experiments

  Nature Machine Intelligence · 2019 · https://doi.org/10.1038/s42256-019-0122-4

• PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells

  Science Translational Medicine · 2018 · https://doi.org/10.1126/scitranslmed.aaq1093

• Methods for High-throughput Drug Combination Screening and Synergy Scoring

  Methods in molecular biology · 2018 · https://doi.org/10.1007/978-1-4939-7493-1_17

• Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions

  Cell chemical biology · 2017 · https://doi.org/10.1016/j.chembiol.2017.11.009

• What is synergy? The Saariselkä agreement revisited

  Frontiers in Pharmacology · 2015 · https://doi.org/10.3389/fphar.2015.00181

• Searching for Drug Synergy in Complex Dose–Response Landscapes Using an Interaction Potency Model

  Computational and Structural Biotechnology Journal · 2015 · https://doi.org/10.1016/j.csbj.2015.09.001

• Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products

  Natural Product Reports · 2015 · https://doi.org/10.1039/c5np00005j

• Making Sense of Large-Scale Kinase Inhibitor Bioactivity Data Sets: A Comparative and Integrative Analysis

  Journal of Chemical Information and Modeling · 2014 · https://doi.org/10.1021/ci400709d

• Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies

  Scientific Reports · 2014 · https://doi.org/10.1038/srep05193

• A community effort to assess and improve drug sensitivity prediction algorithms

  Nature Biotechnology · 2014 · https://doi.org/10.1038/nbt.2877

• Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

  Blood · 2013 · https://doi.org/10.1182/blood-2012-12-474577

• Individualized Systems Medicine Strategy to Tailor Treatments for Patients with Chemorefractory Acute Myeloid Leukemia

  Cancer Discovery · 2013 · https://doi.org/10.1158/2159-8290.cd-13-0350

• Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia

  New England Journal of Medicine · 2012 · https://doi.org/10.1056/nejmoa1114885

Current projects

No projects listed.