Jack B. Cowland

Research interests

Publications

• Granulopoiesis and granules of human neutrophils

  Immunological Reviews · 2016 · https://doi.org/10.1111/imr.12440

• Liver is the major source of elevated serum lipocalin‐2 levels after bacterial infection or partial hepatectomy: A critical role for IL‐6/STAT3

  Hepatology · 2014 · https://doi.org/10.1002/hep.27447

• Olfactomedin 4 defines a subset of human neutrophils

  Journal of Leukocyte Biology · 2011 · https://doi.org/10.1189/jlb.0811417

• Neutrophil granules in health and disease

  Journal of Internal Medicine · 2010 · https://doi.org/10.1111/j.1365-2796.2010.02237.x

• Induction of Neutrophil Gelatinase-associated Lipocalin Expression by Co-stimulation with Interleukin-17 and Tumor Necrosis Factor-α Is Controlled by IκB-ζ but neither by C/EBP-β nor C/EBP-δ

  Journal of Biological Chemistry · 2010 · https://doi.org/10.1074/jbc.m109.017129

• The Genetics of Ficolins

  Journal of Innate Immunity · 2009 · https://doi.org/10.1159/000242419

• MicroRNAs and cancer

  Apmis · 2007 · https://doi.org/10.1111/j.1600-0463.2007.apm_775.xml.x

• Neutrophil gelatinase–associated lipocalin is expressed in osteoarthritis and forms a complex with matrix metalloproteinase 9

  Arthritis & Rheumatism · 2007 · https://doi.org/10.1002/art.22879

• IL-1β-Specific Up-Regulation of Neutrophil Gelatinase-Associated Lipocalin Is Controlled by IκB-ζ

  The Journal of Immunology · 2006 · https://doi.org/10.4049/jimmunol.176.9.5559

• Neutrophil Gelatinase-associated Lipocalin, a Siderophore-binding Eukaryotic Protein

  BioMetals · 2006 · https://doi.org/10.1007/s10534-005-3251-7

• The endocytic receptor megalin binds the iron transporting neutrophil‐gelatinase‐associated lipocalin with high affinity and mediates its cellular uptake

  FEBS Letters · 2004 · https://doi.org/10.1016/j.febslet.2004.12.031

• The transcriptional program of terminal granulocytic differentiation

  Blood · 2004 · https://doi.org/10.1182/blood-2004-08-3346

• Wound Healing and Expression of Antimicrobial Peptides/Polypeptides in Human Keratinocytes, a Consequence of Common Growth Factors

  The Journal of Immunology · 2003 · https://doi.org/10.4049/jimmunol.170.11.5583

• The in vivo profile of transcription factors during neutrophil differentiation in human bone marrow

  Blood · 2003 · https://doi.org/10.1182/blood-2002-03-0835

• Neutrophil Gelatinase-Associated Lipocalin Is Up-Regulated in Human Epithelial Cells by IL-1β, but Not by TNF-α

  The Journal of Immunology · 2003 · https://doi.org/10.4049/jimmunol.171.12.6630

• Human neutrophil gelatinase-associated lipocalin and homologous proteins in rat and mouse

  Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 2000 · https://doi.org/10.1016/s0167-4838(00)00152-7

• The individual regulation of granule protein mRNA levels during neutrophil maturation explains the heterogeneity of neutrophil granules

  Journal of Leukocyte Biology · 1999 · https://doi.org/10.1002/jlb.66.6.989

• The Human Antibacterial Cathelicidin, hCAP-18, Is Synthesized in Myelocytes and Metamyelocytes and Localized to Specific Granules in Neutrophils

  Blood · 1997 · https://doi.org/10.1182/blood.v90.7.2796

• An ELISA for hCAP-18, the cathelicidin present in human neutrophils and plasma

  Journal of Immunological Methods · 1997 · https://doi.org/10.1016/s0022-1759(97)00084-7

• Granules of the Human Neutrophilic Polymorphonuclear Leukocyte

  Blood · 1997 · https://doi.org/10.1182/blood.v89.10.3503

• Molecular Characterization and Pattern of Tissue Expression of the Gene for Neutrophil Gelatinase-Associated Lipocalin from Humans

  Genomics · 1997 · https://doi.org/10.1006/geno.1997.4896

• Targeting of proteins to granule subsets is determined by timing and not by sorting: The specific granule protein NGAL is localized to azurophil granules when expressed in HL-60 cells.

  Proceedings of the National Academy of Sciences · 1996 · https://doi.org/10.1073/pnas.93.13.6454

• hCAP‐18, a cathelin/pro‐bactenecin‐like protein of human neutrophil specific granules

  FEBS Letters · 1995 · https://doi.org/10.1016/0014-5793(95)00634-l

• Primary structure and localization of a conserved immunogenicPlasmodium falciparum glutamate rich protein (GLURP) expressed in both the preerythrocytic and erythrocytic stages of the vertebrate life cycle

  Molecular and Biochemical Parasitology · 1991 · https://doi.org/10.1016/0166-6851(91)90135-s

Current projects

No projects listed.