Martin R. Larsen

Research interests

Publications

• The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis

  Science Immunology · 2024 · 10.1126/sciimmunol.adn1452

• Resolution of NASH and hepatic fibrosis by the GLP-1R and GCGR dual-agonist cotadutide via modulating mitochondrial function and lipogenesis

  Nature Metabolism · 2020 · 10.1038/s42255-020-0209-6

• How many human proteoforms are there?

  Nature Chemical Biology · 2018 · https://doi.org/10.1038/nchembio.2576

• Proteomic Profiling of Mouse Epididymosomes Reveals their Contributions to Post-testicular Sperm Maturation

  Molecular & Cellular Proteomics · 2018 · 10.1074/mcp.ra118.000946

• Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer

  Nature Communications · 2017 · 10.1038/s41467-017-00450-6

• Site-Specific Glycan-Peptide Analysis for Determination of N-Glycoproteome Heterogeneity

  Journal of Proteome Research · 2013 · 10.1021/pr400783j

• MMP Mediated Degradation of Type IV Collagen Alpha 1 and Alpha 3 Chains Reflects Basement Membrane Remodeling in Experimental and Clinical Fibrosis – Validation of Two Novel Biomarker Assays

  PLoS ONE · 2013 · 10.1371/journal.pone.0084934

• Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors

  PROTEOMICS · 2013 · 10.1002/pmic.201300452

• TiSH — a robust and sensitive global phosphoproteomics strategy employing a combination of TiO2, SIMAC, and HILIC

  Journal of Proteomics · 2012 · https://doi.org/10.1016/j.jprot.2012.08.007

• Chemical Deamidation: A Common Pitfall in Large-Scale N-Linked Glycoproteomic Mass Spectrometry-Based Analyses

  Journal of Proteome Research · 2012 · 10.1021/pr2011268

• MMP Mediated Degradation of Type VI Collagen Is Highly Associated with Liver Fibrosis – Identification and Validation of a Novel Biochemical Marker Assay

  PLoS ONE · 2011 · 10.1371/journal.pone.0024753

• Simultaneous Glycan-Peptide Characterization Using Hydrophilic Interaction Chromatography and Parallel Fragmentation by CID, Higher Energy Collisional Dissociation, and Electron Transfer Dissociation MS Applied to the N-Linked Glycoproteome of Campylobacter jejuni

  Molecular & Cellular Proteomics · 2010 · 10.1074/mcp.m000031-mcp201

• A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen

  Clinical Biochemistry · 2010 · 10.1016/j.clinbiochem.2010.03.012

• Selective enrichment of sialic acid–containing glycopeptides using titanium dioxide chromatography with analysis by HILIC and mass spectrometry

  Nature Protocols · 2010 · 10.1038/nprot.2010.167

• Analytical strategies for phosphoproteomics

  PROTEOMICS · 2009 · https://doi.org/10.1002/pmic.200800454

• Evaluation of the impact of some experimental procedures on different phosphopeptide enrichment techniques

  Rapid Communications in Mass Spectrometry · 2007 · 10.1002/rcm.3254

• Exploring the Sialiome Using Titanium Dioxide Chromatography and Mass Spectrometry

  Molecular & Cellular Proteomics · 2007 · 10.1074/mcp.m700086-mcp200

• SIMAC (Sequential Elution from IMAC), a Phosphoproteomics Strategy for the Rapid Separation of Monophosphorylated from Multiply Phosphorylated Peptides

  Molecular & Cellular Proteomics · 2007 · https://doi.org/10.1074/mcp.m700362-mcp200

• Analysis of Posttranslational Modifications of Proteins by Tandem Mass Spectrometry

  BioTechniques · 2006 · 10.2144/000112201

• Proteome Profiling of Populus euphratica Oliv. Upon Heat Stress

  Annals of Botany · 2006 · 10.1093/aob/mcl106

• Highly selective enrichment of phosphorylated peptides using titanium dioxide

  Nature Protocols · 2006 · https://doi.org/10.1038/nprot.2006.185

• Highly Selective Enrichment of Phosphorylated Peptides from Peptide Mixtures Using Titanium Dioxide Microcolumns

  Molecular & Cellular Proteomics · 2005 · https://doi.org/10.1074/mcp.t500007-mcp200

• Cdk5 is essential for synaptic vesicle endocytosis

  Nature Cell Biology · 2003 · 10.1038/ncb1020

• Complementing genomics with proteomics: The membrane subproteome ofPseudomonas aeruginosa PAO1

  Electrophoresis · 2000 · 10.1002/1522-2683(200011)21:17<3797::aid-elps3797>3.0.co;2-p

• Mass spectrometric identification and microcharacterization of proteins from electrophoretic gels: Strategies and applications

  Proteins Structure Function and Bioinformatics · 1998 · 10.1002/(sici)1097-0134(1998)33:2+<74::aid-prot9>3.0.co;2-b

Current projects

No projects listed.