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Sampsa Hautaniemi

Researcher Next ID · RN-039077

Researcher · Biochemistry, Genetics and Molecular Biology

University of Helsinki

Helsinki, Finland

Accepting doctoral researchersFunding unknown
Works count
544
Citation count
12,024
H-index
59
i10-index
152

Research interests

Biochemistry, Genetics and Molecular Biology
Medicine
Ovarian cancer diagnosis and treatment
PARP inhibition in cancer therapy
Cancer Genomics and Diagnostics
Genomic variations and chromosomal abnormalities
DNA Repair Mechanisms

Publications

  • Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer

    Science Advances · 2022 · 10.1126/sciadv.abm1831

  • Longitudinal single-cell RNA-seq analysis reveals stress-promoted chemoresistance in metastatic ovarian cancer

    Science Advances · 2022 · 10.1126/sciadv.abm1831

  • Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance

    Nature Communications · 2021 · 10.1038/s41467-021-24009-8

  • Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance

    Nature Communications · 2021 · 10.1038/s41467-021-24009-8

  • Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

    Nature Communications · 2020 · https://doi.org/10.1038/s41467-020-15315-8

  • Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph nodes

    Journal of Clinical Investigation · 2018 · 10.1172/jci96149

  • Tissue‐specific pioneer factors associate with androgen receptor cistromes and transcription programs

    The EMBO Journal · 2014 · 10.1002/embj.201385895

  • Adipocyte morphology and implications for metabolic derangements in acquired obesity

    International Journal of Obesity · 2014 · 10.1038/ijo.2014.31

  • Characterising metabolically healthy obesity in weight-discordant monozygotic twins

    Diabetologia · 2013 · 10.1007/s00125-013-3066-y

  • FoxA1 Specifies Unique Androgen and Glucocorticoid Receptor Binding Events in Prostate Cancer Cells

    Cancer Research · 2012 · 10.1158/0008-5472.can-12-2350

  • FoxA1 Specifies Unique Androgen and Glucocorticoid Receptor Binding Events in Prostate Cancer Cells

    Cancer Research · 2012 · 10.1158/0008-5472.can-12-2350

  • Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer

    The EMBO Journal · 2011 · https://doi.org/10.1038/emboj.2011.328

  • PINA v2.0: mining interactome modules

    Nucleic Acids Research · 2011 · https://doi.org/10.1093/nar/gkr967

  • KSHV-Initiated Notch Activation Leads to Membrane-Type-1 Matrix Metalloproteinase-Dependent Lymphatic Endothelial-to-Mesenchymal Transition

    Cell Host & Microbe · 2011 · 10.1016/j.chom.2011.10.011

  • Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme

    Genome Medicine · 2010 · 10.1186/gm186

  • Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme

    Genome Medicine · 2010 · 10.1186/gm186

  • Early recovery from cow's milk allergy is associated with decreasing IgE and increasing IgG4 binding to cow's milk epitopes

    Journal of Allergy and Clinical Immunology · 2010 · 10.1016/j.jaci.2010.03.025

  • Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

    Genome biology · 2008 · 10.1186/gb-2008-9-9-r139

  • The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome

    International Journal of Cancer · 2008 · 10.1002/ijc.24017

  • Integrated network analysis platform for protein-protein interactions

    Nature Methods · 2008 · https://doi.org/10.1038/nmeth.1282

  • Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

    Genome biology · 2008 · 10.1186/gb-2008-9-9-r139

  • Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks

    Proceedings of the National Academy of Sciences · 2007 · https://doi.org/10.1073/pnas.0608638104

  • Effects of HER2 overexpression on cell signaling networks governing proliferation and migration

    Molecular Systems Biology · 2006 · 10.1038/msb4100094

  • Effects of HER2 overexpression on cell signaling networks governing proliferation and migration

    Molecular Systems Biology · 2006 · 10.1038/msb4100094

  • Gene-Expression Profiling Predicts Recurrence in Dukes’ C Colorectal Cancer

    Gastroenterology · 2005 · 10.1053/j.gastro.2005.06.066

  • Are data from different gene expression microarray platforms comparable?

    Genomics · 2004 · 10.1016/j.ygeno.2004.01.004

  • Are data from different gene expression microarray platforms comparable?

    Genomics · 2004 · 10.1016/j.ygeno.2004.01.004

  • High-Resolution Analysis of Gene Copy Number Alterations in Human Prostate Cancer Using CGH on cDNA Microarrays: Impact of Copy Number on Gene Expression

    Neoplasia · 2004 · 10.1593/neo.03439

  • Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer

    Nature Genetics · 2004 · 10.1038/ng1408

  • Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer

    Nature Genetics · 2004 · 10.1038/ng1408

  • Optimized LOWESS normalization parameter selection for DNA microarray data

    BMC Bioinformatics · 2004 · 10.1186/1471-2105-5-194

  • RNAi Microarray Analysis in Cultured Mammalian Cells

    Genome Research · 2003 · 10.1101/gr.1478703

  • RNAi Microarray Analysis in Cultured Mammalian Cells

    Genome Research · 2003 · 10.1101/gr.1478703

  • Impact of DNA amplification on gene expression patterns in breast cancer.

    PubMed · 2002

Current projects

    No projects listed.