Ville O. Paavilainen

Researcher Next ID · RN-039083

Researcher · Biochemistry, Genetics and Molecular Biology

Helsinki, Finland

Accepting doctoral researchersFunding unknown

Research interests

Biochemistry, Genetics and Molecular Biology

Medicine

Cellular Mechanics and Interactions

RNA and protein synthesis mechanisms

Cellular transport and secretion

Cardiomyopathy and Myosin Studies

RNA modifications and cancer

Rapamycin-inspired macrocycles with new target specificity
Nature Chemistry · 2018 · 10.1038/s41557-018-0187-4
Mycolactone subverts immunity by selectively blocking the Sec61 translocon
The Journal of Experimental Medicine · 2016 · 10.1084/jem.20160662
Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel
Cell chemical biology · 2016 · 10.1016/j.chembiol.2016.04.008
Prolonged and tunable residence time using reversible covalent kinase inhibitors
Nature Chemical Biology · 2015 · https://doi.org/10.1038/nchembio.1817
Electrophilic Fragment-Based Design of Reversible Covalent Kinase Inhibitors
Journal of the American Chemical Society · 2013 · 10.1021/ja401221b
GMF Is a Cofilin Homolog that Binds Arp2/3 Complex to Stimulate Filament Debranching and Inhibit Actin Nucleation
Current Biology · 2010 · 10.1016/j.cub.2010.03.026
Structure of the actin-depolymerizing factor homology domain in complex with actin
The Journal of Cell Biology · 2008 · 10.1083/jcb.200803100
Missing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain–like mechanism
The Journal of Cell Biology · 2007 · https://doi.org/10.1083/jcb.200609176
Regulation of cytoskeletal dynamics by actin-monomer-binding proteins
Trends in Cell Biology · 2004 · https://doi.org/10.1016/j.tcb.2004.05.002

No projects listed.