Matti Nykter

Research interests

Publications

• Deep whole-genome ctDNA chronology of treatment-resistant prostate cancer

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04975-9

• Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-020-20493-6

• Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease–Associated Colorectal Cancer

  Gastroenterology · 2021 · https://doi.org/10.1053/j.gastro.2021.04.042

• Immunogenomic Landscape of Hematological Malignancies

  Cancer Cell · 2020 · https://doi.org/10.1016/j.ccell.2020.06.002

• Circulating Tumor DNA Abundance and Potential Utility in De Novo Metastatic Prostate Cancer

  European Urology · 2019 · https://doi.org/10.1016/j.eururo.2018.12.042

• Circulating Tumor DNA Genomics Correlate with Resistance to Abiraterone and Enzalutamide in Prostate Cancer

  Cancer Discovery · 2018 · https://doi.org/10.1158/2159-8290.cd-17-0937

• Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-03573-6

• Treatment Outcomes and Tumor Loss of Heterozygosity in Germline DNA Repair–deficient Prostate Cancer

  European Urology · 2017 · https://doi.org/10.1016/j.eururo.2017.02.023

• Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer

  JNCI Journal of the National Cancer Institute · 2017 · https://doi.org/10.1093/jnci/djx118

• Circulating Tumor DNA Reveals Clinically Actionable Somatic Genome of Metastatic Bladder Cancer

  Clinical Cancer Research · 2017 · https://doi.org/10.1158/1078-0432.ccr-17-1140

• Genomic Alterations in Cell-Free DNA and Enzalutamide Resistance in Castration-Resistant Prostate Cancer

  JAMA Oncology · 2016 · https://doi.org/10.1001/jamaoncol.2016.0494

• Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression

  BMC Genomics · 2015 · https://doi.org/10.1186/s12864-015-1381-z

• The evolutionary history of lethal metastatic prostate cancer

  Nature · 2015 · https://doi.org/10.1038/nature14347

• A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.2862

• The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma

  Journal of Clinical Investigation · 2013 · https://doi.org/10.1172/jci67144

• Gene-pair expression signatures reveal lineage control

  Nature Methods · 2013 · https://doi.org/10.1038/nmeth.2445

• Integrated Analyses Identify a Master MicroRNA Regulatory Network for the Mesenchymal Subtype in Serous Ovarian Cancer

  Cancer Cell · 2013 · https://doi.org/10.1016/j.ccr.2012.12.020

• Circulating Plasma MiR-141 Is a Novel Biomarker for Metastatic Colon Cancer and Predicts Poor Prognosis

  PLoS ONE · 2011 · https://doi.org/10.1371/journal.pone.0017745

• Function of C/EBPδ in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals

  Nature Immunology · 2009 · https://doi.org/10.1038/ni.1721

• Gene expression dynamics in the macrophage exhibit criticality

  Proceedings of the National Academy of Sciences · 2008 · https://doi.org/10.1073/pnas.0711525105

Current projects

No projects listed.