Tuomas Mirtti

Research interests

Publications

• The impact of imputation quality on machine learning classifiers for datasets with missing values

  Communications Medicine · 2023 · 10.1038/s43856-023-00356-z

• Spatially resolved clonal copy number alterations in benign and malignant tissue

  Nature · 2022 · https://doi.org/10.1038/s41586-022-05023-2

• Metabolomic Profiling of Extracellular Vesicles and Alternative Normalization Methods Reveal Enriched Metabolites and Strategies to Study Prostate Cancer-Related Changes

  Theranostics · 2017 · https://doi.org/10.7150/thno.19890

• Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data

  The Lancet Oncology · 2016 · https://doi.org/10.1016/s1470-2045(16)30560-5

• Upstaging of urothelial cancer at the time of radical cystectomy: factors associated with upstaging and its effect on outcome

  British Journal of Urology · 2012 · 10.1111/j.1464-410x.2012.10939.x

• Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer

  The EMBO Journal · 2011 · https://doi.org/10.1038/emboj.2011.328

• Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion

  Oncogene · 2011 · https://doi.org/10.1038/onc.2011.512

• Arachidonic Acid Pathway Members PLA2G7, HPGD, EPHX2, and CYP4F8 Identified as Putative Novel Therapeutic Targets in Prostate Cancer

  American Journal Of Pathology · 2011 · https://doi.org/10.1016/j.ajpath.2010.10.002

• FZD4 as a Mediator of ERG Oncogene–Induced WNT Signaling and Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells

  Cancer Research · 2010 · https://doi.org/10.1158/0008-5472.can-10-0244

• Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo

  Endocrine Related Cancer · 2010 · 10.1677/erc-09-0328

• Stat3 Promotes Metastatic Progression of Prostate Cancer

  American Journal Of Pathology · 2008 · https://doi.org/10.2353/ajpath.2008.071054

• Autocrine Prolactin Promotes Prostate Cancer Cell Growth via Janus Kinase-2-Signal Transducer and Activator of Transcription-5a/b Signaling Pathway

  Endocrinology · 2007 · https://doi.org/10.1210/en.2006-1761

Current projects

No projects listed.