Matti Annala

Research interests

Publications

• Deep whole-genome ctDNA chronology of treatment-resistant prostate cancer

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04975-9

• Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-020-20493-6

• Optimal sequencing of enzalutamide and abiraterone acetate plus prednisone in metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase 2, crossover trial

  The Lancet Oncology · 2019 · https://doi.org/10.1016/s1470-2045(19)30688-6

• Circulating Tumor DNA Abundance and Potential Utility in De Novo Metastatic Prostate Cancer

  European Urology · 2019 · https://doi.org/10.1016/j.eururo.2018.12.042

• Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-03573-6

• Circulating Tumor DNA Genomics Correlate with Resistance to Abiraterone and Enzalutamide in Prostate Cancer

  Cancer Discovery · 2018 · https://doi.org/10.1158/2159-8290.cd-17-0937

• Treatment Outcomes and Tumor Loss of Heterozygosity in Germline DNA Repair–deficient Prostate Cancer

  European Urology · 2017 · https://doi.org/10.1016/j.eururo.2017.02.023

• Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer

  JNCI Journal of the National Cancer Institute · 2017 · https://doi.org/10.1093/jnci/djx118

• Analysis of Circulating Cell-Free DNA Identifies Multiclonal Heterogeneity of BRCA2 Reversion Mutations Associated with Resistance to PARP Inhibitors

  Cancer Discovery · 2017 · https://doi.org/10.1158/2159-8290.cd-17-0146

• Circulating Tumor DNA Reveals Clinically Actionable Somatic Genome of Metastatic Bladder Cancer

  Clinical Cancer Research · 2017 · https://doi.org/10.1158/1078-0432.ccr-17-1140

• Genomic Alterations in Cell-Free DNA and Enzalutamide Resistance in Castration-Resistant Prostate Cancer

  JAMA Oncology · 2016 · https://doi.org/10.1001/jamaoncol.2016.0494

• The evolutionary history of lethal metastatic prostate cancer

  Nature · 2015 · https://doi.org/10.1038/nature14347

• The Molecular Taxonomy of Primary Prostate Cancer

  Cell · 2015 · https://doi.org/10.1016/j.cell.2015.10.025

• A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.2862

• The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma

  Journal of Clinical Investigation · 2013 · https://doi.org/10.1172/jci67144

• Evaluation of methods for modeling transcription factor sequence specificity

  Nature Biotechnology · 2013 · https://doi.org/10.1038/nbt.2486

Current projects

No projects listed.