Caroline A. Heckman

Researcher Next ID · RN-039179

Researcher · Biochemistry, Genetics and Molecular Biology

University of Helsinki

Helsinki, Finland

Accepting doctoral researchersFunding unknown

Works count: 457
Citation count: 7,730
H-index: 43
i10-index: 98

Research interests

Biochemistry, Genetics and Molecular Biology

Computer Science

Medicine

Acute Myeloid Leukemia Research

Multiple Myeloma Research and Treatments

Protein Degradation and Inhibitors

Cancer Genomics and Diagnostics

Computational Drug Discovery Methods

Publications

Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia
Cancer Discovery · 2021 · https://doi.org/10.1158/2159-8290.cd-21-0410
Immunogenomic Landscape of Hematological Malignancies
Cancer Cell · 2020 · https://doi.org/10.1016/j.ccell.2020.06.002
Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer
PLoS Computational Biology · 2019 · https://doi.org/10.1371/journal.pcbi.1006752
Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia
Haematologica · 2019 · https://doi.org/10.3324/haematol.2018.214882
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies
Scientific Reports · 2014 · https://doi.org/10.1038/srep05193
Individualized Systems Medicine Strategy to Tailor Treatments for Patients with Chemorefractory Acute Myeloid Leukemia
Cancer Discovery · 2013 · https://doi.org/10.1158/2159-8290.cd-13-0350
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia
Blood · 2013 · https://doi.org/10.1182/blood-2012-12-474577
Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia
New England Journal of Medicine · 2012 · https://doi.org/10.1056/nejmoa1114885
Comparison of solution-based exome capture methods for next generation sequencing
Genome biology · 2011 · https://doi.org/10.1186/gb-2011-12-9-r94
Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors
Genes Chromosomes and Cancer · 2010 · https://doi.org/10.1002/gcc.20815
Functional interaction of VEGF‐C and VEGF‐D with neuropilin receptors
The FASEB Journal · 2006 · https://doi.org/10.1096/fj.05-5646com
Histone Deacetylase Inhibitors Down-Regulate bcl-2 Expression and Induce Apoptosis in t(14;18) Lymphomas
Molecular and Cellular Biology · 2005 · https://doi.org/10.1128/mcb.25.5.1608-1619.2005
Negative regulation of bcl-2 expression by p53 in hematopoietic cells
Oncogene · 2001 · https://doi.org/10.1038/sj.onc.1204067

Current projects

No projects listed.