Pauli Puolakkainen

Research interests

Publications

• SIRT2‐dependent IDH1 deacetylation inhibits colorectal cancer and liver metastases

  EMBO Reports · 2020 · 10.15252/embr.201948183

• Toward a Consensus on Centralization in Surgery

  Annals of Surgery · 2018 · https://doi.org/10.1097/sla.0000000000002965

• Biomaterial topography alters healing in vivo and monocyte/macrophage activation in vitro

  Journal of Biomedical Materials Research Part A · 2010 · 10.1002/jbm.a.32893

• A Prospective Diagnostic Accuracy Study of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography, Multidetector Row Computed Tomography, and Magnetic Resonance Imaging in Primary Diagnosis and Staging of Pancreatic Cancer

  Annals of Surgery · 2009 · https://doi.org/10.1097/sla.0b013e3181b2fafa

• FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

  The Journal of Cell Biology · 2009 · https://doi.org/10.1083/jcb.200901104

• Transcription Factor PROX1 Induces Colon Cancer Progression by Promoting the Transition from Benign to Highly Dysplastic Phenotype

  Cancer Cell · 2008 · https://doi.org/10.1016/j.ccr.2008.02.020

• Early Assessment of Pancreatic Infections and Overall Prognosis in Severe Acute Pancreatitis by Procalcitonin (PCT)

  Annals of Surgery · 2007 · https://doi.org/10.1097/01.sla.0000252443.22360.46

• A role for decorin in cutaneous wound healing and angiogenesis

  Wound Repair and Regeneration · 2006 · 10.1111/j.1743-6109.2006.00150.x

• Early prediction of organ failure by combined markers in patients with acute pancreatitis

  British journal of surgery · 2004 · 10.1002/bjs.4786

• Enhanced Growth of Pancreatic Tumors in SPARC-Null Mice Is Associated With Decreased Deposition of Extracellular Matrix and Reduced Tumor Cell Apoptosis

  Molecular Cancer Research · 2004 · 10.1158/1541-7786.215.2.4

• Enhanced growth of tumors in SPARC null mice is associated with changes in the ECM

  Journal of Clinical Investigation · 2003 · https://doi.org/10.1172/jci16804

• Spontaneous disappearance of Helicobacter pylori antibodies in patients with advanced atrophic corpus gastritis

  Apmis · 2003 · 10.1034/j.1600-0463.2003.1110604.x

• SPARC-Null Mice Display Abnormalities in the Dermis Characterized by Decreased Collagen Fibril Diameter and Reduced Tensile Strength

  Journal of Investigative Dermatology · 2003 · https://doi.org/10.1046/j.1523-1747.2003.12241.x

• Cleavage of the Matricellular Protein SPARC by Matrix Metalloproteinase 3 Produces Polypeptides That Influence Angiogenesis

  Journal of Biological Chemistry · 2003 · 10.1074/jbc.m302946200

• Multiple organ dysfunction associated with severe acute pancreatitis*

  Critical Care Medicine · 2002 · https://doi.org/10.1097/00003246-200206000-00019

• Vascular Endothelial Growth Factor Receptor-3 in Lymphangiogenesis in Wound Healing

  American Journal Of Pathology · 2000 · https://doi.org/10.1016/s0002-9440(10)65021-3

• Severe Acute Pancreatitis: Prognostic Factors in 270 Consecutive Patients

  Pancreas · 2000 · 10.1097/00006676-200010000-00008

• Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations.

  PubMed · 1998

• Rapid Measurement of Urinary Trypsinogen-2 as a Screening Test for Acute Pancreatitis

  New England Journal of Medicine · 1997 · 10.1056/nejm199706193362504

• Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers.

  PubMed · 1996

• Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds.

  PubMed · 1996

• Early antibiotic treatment in acute necrotising pancreatitis

  The Lancet · 1995 · https://doi.org/10.1016/s0140-6736(95)92280-6

• Calcium-alginate beads for the oral delivery of transforming growth factor-β1 (TGF-β1): stabilization of TGF-β1 by the addition of polyacrylic acid within acid-treated beads

  Journal of Controlled Release · 1994 · https://doi.org/10.1016/0168-3659(94)90030-2

• Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization.

  Journal of Histochemistry & Cytochemistry · 1993 · https://doi.org/10.1177/41.10.8245406

• C-reactive protein (CRP) and serum phospholipase A2 in the assessment of the severity of acute pancreatitis.

  Gut · 1987 · 10.1136/gut.28.6.764

Current projects

No projects listed.