Ralf Bützow

Research interests

Publications

• Clinicopathological significance of deficient DNA mismatch repair and MLH1 promoter methylation in endometrioid endometrial carcinoma

  Modern Pathology · 2020 · 10.1038/s41379-020-0501-8

• Clinicopathological significance of deficient DNA mismatch repair and MLH1 promoter methylation in endometrioid endometrial carcinoma

  Modern Pathology · 2020 · 10.1038/s41379-020-0501-8

• Shared heritability and functional enrichment across six solid cancers

  Nature Communications · 2019 · https://doi.org/10.1038/s41467-018-08054-4

• Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms12675

• Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study

  International Journal of Epidemiology · 2016 · 10.1093/ije/dyw207

• Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12

  PLoS Genetics · 2016 · 10.1371/journal.pgen.1005850

• Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study

  International Journal of Epidemiology · 2016 · 10.1093/ije/dyw207

• Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers

  Proceedings of the National Academy of Sciences · 2016 · https://doi.org/10.1073/pnas.1518752113

• Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12

  PLoS Genetics · 2016 · 10.1371/journal.pgen.1005850

• Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

  PLoS ONE · 2015 · https://doi.org/10.1371/journal.pone.0128106

• Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer

  Proceedings of the National Academy of Sciences · 2014 · 10.1073/pnas.1407909111

• Exome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancer

  Proceedings of the National Academy of Sciences · 2014 · 10.1073/pnas.1407909111

• GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2564

• Characterization of Uterine Leiomyomas by Whole-Genome Sequencing

  New England Journal of Medicine · 2013 · 10.1056/nejmoa1302736

• RAD51C is a susceptibility gene for ovarian cancer

  Human Molecular Genetics · 2011 · 10.1093/hmg/ddr229

• RAD51C is a susceptibility gene for ovarian cancer

  Human Molecular Genetics · 2011 · 10.1093/hmg/ddr229

• Distinct Expression Levels and Patterns of Stem Cell Marker, Aldehyde Dehydrogenase Isoform 1 (ALDH1), in Human Epithelial Cancers

  PLoS ONE · 2010 · https://doi.org/10.1371/journal.pone.0010277

• The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary

  Modern Pathology · 2010 · https://doi.org/10.1038/modpathol.2010.145

• Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1–Positive Cancer Stem Cells

  Cancer Research · 2010 · 10.1158/0008-5472.can-10-2388

• Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1–Positive Cancer Stem Cells

  Cancer Research · 2010 · 10.1158/0008-5472.can-10-2388

• Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

  Proceedings of the National Academy of Sciences · 2008 · https://doi.org/10.1073/pnas.0801615105

• MicroRNA Microarray Identifies Let-7i as a Novel Biomarker and Therapeutic Target in Human Epithelial Ovarian Cancer

  Cancer Research · 2008 · 10.1158/0008-5472.can-08-1954

• Integrative Genomic Analysis of Phosphatidylinositol 3′-Kinase Family Identifies PIK3R3 as a Potential Therapeutic Target in Epithelial Ovarian Cancer

  Clinical Cancer Research · 2007 · 10.1158/1078-0432.ccr-06-2660

• Integrative Genomic Analysis of Phosphatidylinositol 3′-Kinase Family Identifies PIK3R3 as a Potential Therapeutic Target in Epithelial Ovarian Cancer

  Clinical Cancer Research · 2007 · 10.1158/1078-0432.ccr-06-2660

• Surveillance for endometrial cancer in hereditary nonpolyposis colorectal cancer syndrome

  International Journal of Cancer · 2006 · https://doi.org/10.1002/ijc.22446

• Gene amplification, mutation, and protein expression of EGFR and mutations of ERBB2 in serous ovarian carcinoma

  Journal of Molecular Medicine · 2006 · 10.1007/s00109-006-0054-4

• Gene amplification, mutation, and protein expression of EGFR and mutations of ERBB2 in serous ovarian carcinoma

  Journal of Molecular Medicine · 2006 · 10.1007/s00109-006-0054-4

• Molecular Analysis of Familial Endometrial Carcinoma: A Manifestation of Hereditary Nonpolyposis Colorectal Cancer or a Separate Syndrome?

  Journal of Clinical Oncology · 2005 · 10.1200/jco.2005.06.055

• Molecular Analysis of Familial Endometrial Carcinoma: A Manifestation of Hereditary Nonpolyposis Colorectal Cancer or a Separate Syndrome?

  Journal of Clinical Oncology · 2005 · 10.1200/jco.2005.06.055

• Pathology of Ovarian Cancers in BRCA1 and BRCA2 Carriers

  Clinical Cancer Research · 2004 · 10.1158/1078-0432.ccr-1029-3

• Cytoplasmic HuR expression correlates with poor outcome and with cyclooxygenase 2 expression in serous ovarian carcinoma.

  PubMed · 2003

• Cytoplasmic HuR expression correlates with poor outcome and with cyclooxygenase 2 expression in serous ovarian carcinoma.

  PubMed · 2003

• The Clinical Features of Ovarian Cancer in Hereditary Nonpolyposis Colorectal Cancer

  Gynecologic Oncology · 2001 · https://doi.org/10.1006/gyno.2001.6279

• Transcription Factors GATA-4 and GATA-6 and a GATA Family Cofactor, FOG-2, Are Expressed in Human Ovary and Sex Cord-Derived Ovarian Tumors*

  The Journal of Clinical Endocrinology & Metabolism · 2000 · 10.1210/jcem.85.9.6828

• Transcription Factors GATA-4 and GATA-6 and a GATA Family Cofactor, FOG-2, Are Expressed in Human Ovary and Sex Cord-Derived Ovarian Tumors*

  The Journal of Clinical Endocrinology & Metabolism · 2000 · 10.1210/jcem.85.9.6828

• LKB1 Somatic Mutations in Sporadic Tumors

  American Journal Of Pathology · 1999 · 10.1016/s0002-9440(10)65314-x

• Human Growth Differentiation Factor 9 (GDF-9) and Its Novel Homolog GDF-9B Are Expressed in Oocytes during Early Folliculogenesis1

  The Journal of Clinical Endocrinology & Metabolism · 1999 · 10.1210/jcem.84.8.5921

• LKB1 Somatic Mutations in Sporadic Tumors

  American Journal Of Pathology · 1999 · 10.1016/s0002-9440(10)65314-x

Current projects

No projects listed.