Heikki Ruskoaho

Research interests

Publications

• Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality

  Journal of Internal Medicine · 2018 · 10.1111/joim.12783

• Molecular Atlas of Postnatal Mouse Heart Development

  Journal of the American Heart Association · 2018 · 10.1161/jaha.118.010378

• Drug‐Loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling

  Small · 2017 · 10.1002/smll.201701276

• Cardiac fibrosis in myocardial infarction—from repair and remodeling to regeneration

  Cell and Tissue Research · 2016 · https://doi.org/10.1007/s00441-016-2431-9

• Collagen XV Is Necessary for Modeling of the Extracellular Matrix and Its Deficiency Predisposes to Cardiomyopathy

  Circulation Research · 2010 · 10.1161/circresaha.110.222133

• Distinct Upregulation of Extracellular Matrix Genes in Transition From Hypertrophy to Hypertensive Heart Failure

  Hypertension · 2005 · 10.1161/01.hyp.0000161873.27088.4c

• Molecular Heterogeneity Has a Major Impact on the Measurement of Circulating N-Terminal Fragments of A- and B-Type Natriuretic Peptides

  Clinical Chemistry · 2004 · 10.1373/clinchem.2004.032490

• A role for cardiac mast cells in the pathogenesis of hypertensive heart disease

  Journal of Hypertension · 2003 · 10.1097/00004872-200310000-00022

• Cardiac Hormones as Diagnostic Tools in Heart Failure

  Endocrine Reviews · 2003 · 10.1210/er.2003-0006

• GATA-4 Is a Nuclear Mediator of Mechanical Stretch-activated Hypertrophic Program

  Journal of Biological Chemistry · 2003 · 10.1074/jbc.m302719200

• Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure

  Biochemical and Biophysical Research Communications · 2003 · 10.1016/s0006-291x(03)01424-4

• Apelin, the Novel Endogenous Ligand of the Orphan Receptor APJ, Regulates Cardiac Contractility

  Circulation Research · 2002 · https://doi.org/10.1161/01.res.0000033522.37861.69

• Endothelial Dysfunction and Salt-Sensitive Hypertension in Spontaneously Diabetic Goto-Kakizaki Rats

  Hypertension · 2001 · 10.1161/01.hyp.37.2.433

• Lack of type XV collagen causes a skeletal myopathy and cardiovascular defects in mice

  Proceedings of the National Academy of Sciences · 2001 · 10.1073/pnas.98.3.1194

• Evidence for cAMP-Independent Mechanisms Mediating the Effects of Adrenomedullin, a New Inotropic Peptide

  Circulation · 1998 · 10.1161/01.cir.97.11.1062

• Mechanisms of mechanical load-induced atrial natriuretic peptide secretion: role of endothelin, nitric oxide, and angiotensin II

  Journal of Molecular Medicine · 1997 · 10.1007/s001090050179

• Brain natriuretic peptide in plasma, atria, and ventricles of vasopressin- and phenylephrine-infused conscious rats.

  Endocrinology · 1994 · 10.1210/endo.134.6.8194476

• Hypoxia stimulates release of ANP and BNP from perfused rat ventricular myocardium

  American Journal of Physiology-Heart and Circulatory Physiology · 1994 · 10.1152/ajpheart.1994.266.4.h1572

• Atrial stretch induces rapid increase in brain natriuretic peptide but not in atrial natriuretic peptide gene expression in vitro.

  Endocrinology · 1993 · 10.1210/endo.133.3.8365376

• Mechanisms of atrial and brain natriuretic peptide release from rat ventricular myocardium: effect of stretching.

  Endocrinology · 1993 · https://doi.org/10.1210/endo.132.5.8477647

• Atrial natriuretic peptide: synthesis, release, and metabolism.

  Pharmacological Reviews · 1992 · https://doi.org/10.1016/s0031-6997(25)00456-9

• Effects of dexmedetomidine, a selective α2-adrenoceptor agonist, on hemodynamic control mechanisms

  Clinical Pharmacology & Therapeutics · 1989 · 10.1038/clpt.1989.103

• EVIDENCE FOR MEDETOMIDINE AS A SELECTIVE AND POTENT AGONIST α2‐ADRENORECEPTORS

  Journal of Autonomic Pharmacology · 1986 · 10.1111/j.1474-8673.1986.tb00654.x

• Atrial natriuretic peptide secretion: Synergistic effect of phorbol ester and A23187

  Biochemical and Biophysical Research Communications · 1985 · 10.1016/0006-291x(85)90945-3

• Atrial natriuretic factor—a circulating hormone stimulated by volume loading

  Nature · 1985 · https://doi.org/10.1038/314264a0

Current projects

No projects listed.