Matthias Kloor

Research interests

Publications

• Tumour mutational burden: clinical utility, challenges and emerging improvements

  Nature Reviews Clinical Oncology · 2024 · https://doi.org/10.1038/s41571-024-00932-9

• Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study

  The Lancet Oncology · 2021 · https://doi.org/10.1016/s1470-2045(21)00189-3

• European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

  British journal of surgery · 2020 · https://doi.org/10.1002/bjs.11902

• Three molecular pathways model colorectal carcinogenesis in L ynch syndrome

  International Journal of Cancer · 2018 · https://doi.org/10.1002/ijc.31300

• No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies

  Gastroenterology · 2018 · https://doi.org/10.1053/j.gastro.2018.07.030

• Colorectal mixed adenoneuroendocrine carcinomas and neuroendocrine carcinomas are genetically closely related to colorectal adenocarcinomas

  Modern Pathology · 2017 · https://doi.org/10.1038/modpathol.2016.220

• The Immune Biology of Microsatellite-Unstable Cancer

  Trends in cancer · 2016 · https://doi.org/10.1016/j.trecan.2016.02.004

• Potential of fecal microbiota for early‐stage detection of colorectal cancer

  Molecular Systems Biology · 2014 · https://doi.org/10.15252/msb.20145645

• Immune Escape and Survival Mechanisms in Circulating Tumor Cells of Colorectal Cancer

  Cancer Research · 2014 · https://doi.org/10.1158/0008-5472.can-13-1885

• Genetic Evolution of T-cell Resistance in the Course of Melanoma Progression

  Clinical Cancer Research · 2014 · https://doi.org/10.1158/1078-0432.ccr-14-0567

• Colorectal cancer

  The Lancet · 2013 · https://doi.org/10.1016/s0140-6736(13)61649-9

• Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue

  Cancer Immunology Immunotherapy · 2013 · https://doi.org/10.1007/s00262-013-1446-2

• Prevalence of mismatch repair-deficient crypt foci in Lynch syndrome: a pathological study

  The Lancet Oncology · 2012 · https://doi.org/10.1016/s1470-2045(12)70109-2

• Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy

  Cancer Research · 2011 · https://doi.org/10.1158/0008-5472.can-11-0268

• Natural Killer Cells are Scarce in Colorectal Carcinoma Tissue Despite High Levels of Chemokines and Cytokines

  Clinical Cancer Research · 2011 · https://doi.org/10.1158/1078-0432.ccr-10-2173

• Recurrence and variability of germline EPCAM deletions in Lynch syndrome

  Human Mutation · 2011 · https://doi.org/10.1002/humu.21446

• Overexpression of ZEB2 at the Invasion Front of Colorectal Cancer Is an Independent Prognostic Marker and Regulates Tumor Invasion In Vitro

  Clinical Cancer Research · 2011 · https://doi.org/10.1158/1078-0432.ccr-10-2816

• Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study

  The Lancet Oncology · 2010 · https://doi.org/10.1016/s1470-2045(10)70265-5

• Efficacy of Annual Colonoscopic Surveillance in Individuals With Hereditary Nonpolyposis Colorectal Cancer

  Clinical Gastroenterology and Hepatology · 2009 · https://doi.org/10.1016/j.cgh.2009.10.003

• Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers

  Gastroenterology · 2008 · https://doi.org/10.1053/j.gastro.2008.01.015

• Genotype-Phenotype Comparison of German MLH1 and MSH2 Mutation Carriers Clinically Affected With Lynch Syndrome: A Report by the German HNPCC Consortium

  Journal of Clinical Oncology · 2006 · https://doi.org/10.1200/jco.2005.03.7333

• Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases

  British Journal of Cancer · 2005 · https://doi.org/10.1038/sj.bjc.6602534

• Immunoselective Pressure and Human Leukocyte Antigen Class I Antigen Machinery Defects in Microsatellite Unstable Colorectal Cancers

  Cancer Research · 2005 · https://doi.org/10.1158/0008-5472.can-05-0044

Current projects

No projects listed.