Olavi Pelkonen

Researcher Next ID · RN-039404

Researcher · Biochemistry, Genetics and Molecular Biology

University of Oulu

Oulu, Finland

Accepting doctoral researchersFunding unknown

Works count: 356
Citation count: 17,872
H-index: 70
i10-index: 261

Research interests

Biochemistry, Genetics and Molecular Biology

Medicine

Pharmacology, Toxicology and Pharmaceutics

Pharmacogenetics and Drug Metabolism

Drug Transport and Resistance Mechanisms

Carcinogens and Genotoxicity Assessment

Drug-Induced Hepatotoxicity and Protection

Eicosanoids and Hypertension Pharmacology

Publications

Inhibition and induction of CYP enzymes in humans: an update
Archives of Toxicology · 2020 · https://doi.org/10.1007/s00204-020-02936-7
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010
Archives of Toxicology · 2011 · https://doi.org/10.1007/s00204-011-0693-2
Inhibition and induction of human cytochrome P450 enzymes: current status
Archives of Toxicology · 2008 · https://doi.org/10.1007/s00204-008-0332-8
Metabolism: A Bottleneck in In Vitro Toxicological Test Development
Alternatives to Laboratory Animals · 2006 · https://doi.org/10.1177/026119290603400113
Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver
Current Drug Metabolism · 2006 · https://doi.org/10.2174/138920007779315053
Human placenta: a human organ for developmental toxicology research and biomonitoring
Placenta · 2004 · https://doi.org/10.1016/j.placenta.2004.09.006
Expression and Regulation of Xenobiotic-Metabolizing Cytochrome P450 (CYP) Enzymes in Human Lung
Critical Reviews in Toxicology · 2002 · https://doi.org/10.1080/20024091064273
CYP2A6: a human coumarin 7-hydroxylase
Toxicology · 2000 · https://doi.org/10.1016/s0300-483x(99)00200-0
Characterisation and PCR‐based detection of a CYP2A6 gene deletion found at a high frequency in a Chinese population
FEBS Letters · 1999 · https://doi.org/10.1016/s0014-5793(99)00359-2
Xenobiotic-Metabolizing Cytochrome P450 Enzymes in the Human Feto-Placental Unit: Role in Intrauterine Toxicity
Critical Reviews in Toxicology · 1998 · https://doi.org/10.1080/10408449891344173
Age and cytochrome P450-linked drug metabolism in humans: An analysis of 226 subjects with equal histopathologic conditions*
Clinical Pharmacology & Therapeutics · 1997 · https://doi.org/10.1016/s0009-9236(97)90166-1
Expression of xenobiotic-metabolizing cytochrome P450 Forms in human full-term placenta
Biochemical Pharmacology · 1996 · https://doi.org/10.1016/0006-2952(95)02184-1
A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.
PubMed · 1995
Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility-a review
Gene · 1995 · https://doi.org/10.1016/0378-1119(94)00448-2
Metabolism of polycyclic aromatic hydrocarbons: etiologic role in carcinogenesis.
Pharmacological Reviews · 1982 · https://doi.org/10.1016/s0031-6997(25)00051-1

Current projects

No projects listed.