Maria Dêbiec‐Rychter

Research interests

Publications

• Crizotinib in patients with advanced, inoperable inflammatory myofibroblastic tumours with and without anaplastic lymphoma kinase gene alterations (European Organisation for Research and Treatment of Cancer 90101 CREATE): a multicentre, single-drug, prospective, non-randomised phase 2 trial

  The Lancet Respiratory Medicine · 2018 · 10.1016/s2213-2600(18)30116-4

• Toward Minimal Residual Disease-Directed Therapy in Melanoma

  Cell · 2018 · https://doi.org/10.1016/j.cell.2018.06.025

• Tumor Genotype Is an Independent Prognostic Factor in Primary Gastrointestinal Stromal Tumors of Gastric Origin: A European Multicenter Analysis Based on ConticaGIST

  Clinical Cancer Research · 2014 · 10.1158/1078-0432.ccr-14-1677

• Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor

  Genes Chromosomes and Cancer · 2013 · https://doi.org/10.1002/gcc.22083

• 14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma

  Proceedings of the National Academy of Sciences · 2012 · 10.1073/pnas.1115528109

• Crenolanib Inhibits the Drug-Resistant PDGFRA D842V Mutation Associated with Imatinib-Resistant Gastrointestinal Stromal Tumors

  Clinical Cancer Research · 2012 · 10.1158/1078-0432.ccr-12-0625

• Outcome of Patients with Platelet-Derived Growth Factor Receptor Alpha–Mutated Gastrointestinal Stromal Tumors in the Tyrosine Kinase Inhibitor Era

  Clinical Cancer Research · 2012 · 10.1158/1078-0432.ccr-11-3025

• The Clinicopathologic Features of YWHAE-FAM22 Endometrial Stromal Sarcomas

  The American Journal of Surgical Pathology · 2012 · 10.1097/pas.0b013e31824a7b1a

• Identification of a Disease-Defining Gene Fusion in Epithelioid Hemangioendothelioma

  Science Translational Medicine · 2011 · 10.1126/scitranslmed.3002409

• Atypical neurofibromas in neurofibromatosis type 1 are premalignant tumors

  Genes Chromosomes and Cancer · 2011 · 10.1002/gcc.20921

• Imatinib Mesylate in Advanced Dermatofibrosarcoma Protuberans: Pooled Analysis of Two Phase II Clinical Trials

  Journal of Clinical Oncology · 2010 · 10.1200/jco.2009.25.7899

• Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST)

  Proceedings of the National Academy of Sciences · 2010 · 10.1073/pnas.1000248107

• Clinical management of uterine sarcomas

  The Lancet Oncology · 2009 · 10.1016/s1470-2045(09)70226-8

• Clinical Usefulness of EGFR Gene Copy Number as a Predictive Marker in Colorectal Cancer Patients Treated with Cetuximab: A Fluorescent In situ Hybridization Study

  Clinical Cancer Research · 2008 · 10.1158/1078-0432.ccr-08-0449

• Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases

  Modern Pathology · 2008 · 10.1038/modpathol.2008.2

• NCCN Task Force Report: Management of Patients with Gastrointestinal Stromal Tumor (GIST)—Update of the NCCN Clinical Practice Guidelines

  Journal of the National Comprehensive Cancer Network · 2007 · https://doi.org/10.6004/jnccn.2007.2002

• KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours

  European Journal of Cancer · 2006 · https://doi.org/10.1016/j.ejca.2006.01.030

• Efficacy of the Kinase Inhibitor SU11248 against Gastrointestinal Stromal Tumor Mutants Refractory to Imatinib Mesylate

  Clinical Cancer Research · 2006 · 10.1158/1078-0432.ccr-05-2275

• Molecular pathogenesis of multiple gastrointestinal stromal tumors in NF1 patients

  Human Molecular Genetics · 2006 · 10.1093/hmg/ddl016

• Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants

  Gastroenterology · 2005 · https://doi.org/10.1053/j.gastro.2004.11.020

• Molecular and Clinical Analysis of Locally Advanced Dermatofibrosarcoma Protuberans Treated With Imatinib: Imatinib Target Exploration Consortium Study B2225

  Journal of Clinical Oncology · 2005 · https://doi.org/10.1200/jco.2005.07.088

• Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma Group

  European Journal of Cancer · 2004 · 10.1016/j.ejca.2003.11.025

• Activation of the GLI Oncogene through Fusion with the β-Actin Gene (ACTB) in a Group of Distinctive Pericytic Neoplasms

  American Journal Of Pathology · 2004 · 10.1016/s0002-9440(10)63723-6

• Gastrointestinal stromal tumours (GISTs) negative for KIT (CD117 antigen) immunoreactivity

  The Journal of Pathology · 2004 · 10.1002/path.1546

• PRCC-TFE3 Renal Carcinomas

  The American Journal of Surgical Pathology · 2002 · 10.1097/00000478-200212000-00003

Current projects

No projects listed.